Study was carried out to find out the trends and rates of antibiotics prescribing by the physicians. Some patients and pharmacists were interviewed with prepared questionnaires. A study was conducted on the patients who are visiting to civil hospital, rural and primary health centers in Bhandara district. A total of 350 prescriptions were evaluated. For evolution of Prescriptions we follow the National list of essential medicine 2009 and Local guidelines for Prescription pattern. Among those 62.28 % of prescriptions were contain antibiotics and 37.72 % were not contain antibiotics. It indicates that the prescribing rate of antibiotics is higher. While evaluating prescriptions we observed that there were some common errors in prescribing antibiotic like, use of an antibiotics agents with inappropriate spectrum, unnecessary prescription of antibiotics, incorrect dosage and antibiotics were prescribed for viral infections that does not affect the viruses. This may leads to the development of antibiotic resistant bacterial population. Because of this some efforts should be made like, promotion of good Prescription practices, physicians should follow the local guidelines, design education programme for pharmacist, nurses __ampersandsignamp; other professionals working in these settings.