Aim: Plants biomass extract have very important role for the synthesis of different nanoparticles due to its reducing capability, availability and nontoxicity. The present study reports a very easy and green synthesis of poly (vinyl alcohol) stabilized silver nanoparticles using Simul (Bombax ceiba) flower extract. Methodology: The aqueous extract of Simul (Bombax ceiba) flower was used for this bio-reduction. When PVA supported aqueous silver ions exposed to aqueous Simul flower extract, silver ions were reduced and result was green synthesis of silver nanoparticles. Results: The produced silver nanoparticles were characterised by different technique which includes UV__ampersandsignndash;vis spectroscopy and transmission electron microscopy (TEM). The highest peak at 470 nm in UV-visible spectrum due to surface Plasmon resonance confirmed the presence of silver nanoparticles. TEM analysis showed the spherical and irregular particles shape and size ranging from 20 to 100 nm. Conclusion: This single-pot method for synthesis of silver nanoparticle is eco-friendly and cost effective than other hazardous chemical methods. Different therapeutic use of PVA-supported silver nanoparticles synthesized from Simul flower, otherwise thrown away as ineffective material into environment is note worthy.