Objective: To find out and compare the effect of prophylactic knee brace on static balance among collegiate football player in dominant and non dominant leg. Design: Experimental study. Setting: Jamia Hamdard University, Participants: 60 male healthy collegiate football players. Main Outcome Measure: Static balance. Results: It was seen that the two groups i.e. dominant leg and non dominant leg has yielded no significant improvement in static balance within group and between groups. There was no significance difference data in static balance in dominant leg without brace and with brace (p=0.983) and non dominant leg without brace and with brace (p=0.53). Between groups analysis there was also no significant differences in static balance (p=0.993). Conclusion: The finding suggests that there was no improvement in static balance in dominant and non dominant leg without brace and with brace in healthy collegiate football player.