Aim and Objective: Peri-implantitis is a chronic progressive marginal infection which is defined as an inflammatory reaction affecting the tissues surrounding osseointegrated dental implants resulting in loss of supporting bone. The microflora of patients with implants who are edentulous mainly consists of gram positive facultative cocci and non motile rods. Predominantly Streptococcus sanguis, Streptococcus mitis are found in a healthy, stable implant whereas motile rods, Spirochetes, Fusiforms and filaments are infrequently found. Microbiota around the failing implant in edentulous patients usually consists of gram negative anaerobic rods. In partially edentulous patients, peri implant microorganisms in a stable implant majorly consists of motile rods, Spirochetes and cocci. In a failing implant in partially edentulous patients high proportions of P.micros, P.intermedia, C.rectus and Fusobacterium species were observed (Alcoforado et al in 1994). The concept that the composition of subgingival microflora around implants in partially edentulous patients is said to be resultant of composition of flora around the teeth. Based on this principle we set out to identify the presence of putative periodontal pathogens on teeth in a predominantly edentulous arch with a metallic coping with periodontitis and a site in the same mouth with peri__ampersandsignnbsp;implantitis. Materials and Method: Subgingival plaque samples were collected from a partially edentulous patient using a paper point from the periimplantitis lesion with a probing depth of 8-9mm and a tooth with deepest pocket with a probing depth of 6mm and we analyzed the five putative periodontal pathogens namely, P.gingivalis, P.intermedia, P.nigrecens, T.denticola and T.forcythia using Real Time Polymerised Chain Reaction (RTPCR) technique. Results: P.Gingivalis and P.Intermedia , P.Nigrecens had a 3 fold increase and T.Denticola had 1 fold increase when compared to the periodontitis ( teeth) site, and T.Forsythia was found in trace amounts at the periimplantitis site and was completely absent at the periodontitis( teeth) site.