Objective: A study was conducted to know bacteriological profile and antibiogram pattern of lower respiratory tract infection (LRTI) in a rural setup. Methods: Sputum samples from 95 patients with symptoms of LRTI and endotracheal aspirates from 5 patients admitted to intensive care unit (ICU) were processed for culture and antibiotic sensitivity test was done to commonly used antibiotics. Results: Aetiological diagnosis was possible in 83 patients. Sixty five patients were culture positive for single pathogen and 18 patients were culture positive for two pathogens. Males (n=63) were found more at risk to LRTI than females (n=37).LRTI was found more prevalent in 51-60 year age group (n=24). K.pneumoniae (31.3%) was the commonest single pathogen isolated followed by Coagulase positive Staphylococci (26.5%), Streptococcus pneumoniae (15.6%) and Pseudomonas aeruginosa(3.6%). Str. pneuminiae strains were sensitive to ciprofloxacin (95%) and erythromycin (89%),but resistant to ampicillin(31.5%). K.pneumoniae and Pseu.aeruginosa strains were sensitive to ofloxacin (95-100%) ;and cefotaxime and ceftriaxone(67-100%). Conclusion: The present study reveals that K.pneumoniae is the emerging pathogen of LRTI in rural setup with a low prevalence of antibiotic resistance among the pathogens.