Back Ground and Objective: This study was to know and compare the extent of ill effect of cervical radilculopathy in upper limb, by measuring the hand grip strength and hand functions comparing with the normal or unaffected side. Materials and Method: It was a retrospective covariance study, where 30 subjects were selected who satisfied the inclusion and exclusion criteria with a mean age group of 45. All the subjects were explained about the procedures and an informed written consent was obtained. The 30 patients were assessed for grip strength by hand dynamometer and hand function by Jebsen __ampersandsignndash; Taylor hand function test. The assessments were taken three times with an adequate interval of five minutes and the average values were taken. Results: The grip strength and hand functions of the affected side were compared with the unaffected or normal side. Paired and independent t test was used for the analysis of data. High significance was seen in hand grip strength with P = 0.028 P__ampersandsignlt; 0.05 between affected and unaffected side. Hand function data was analyzed by independent t test for the seven sub tests, in which five tests showed very high significance with P= 0.000, 0.015, 0.000,0.000, 0.043 P __ampersandsignlt; 0.05. Interpretation of Results: Hand grip strength and hand functions were significantly reduced in patients with cervical radiculopathy. There was significant reduction in the hand grip strength and hand function in the patients with unilateral cervical radiculopathy when compared with the unaffected side.