Background and aims: 72% of Indian population lives in rural area, where their main occupation is agriculture. Agriculture workers do not have trade unions and have no access to occupational health services. The present study was aimed to know the morbidities of agricultural workers. Methods and Material: This cross-sectional study was done from January 2009 to December 2009 among 400 agricultural workers of age 16 to 60 years residing at a sub-centre area of the PHC administrated by Medical College in South India, using predesigned and pretested questionnaire. Statistical analysis was done by using percentages and chi square test. Results: Among the study participants 55.75% were men and 44.25% were women, with male to female ratio of 1.25:1. Most of the agricultural workers (89.5%) were Hindus and 47% were illiterates; of the 400 study participants, 295 (73.75%) belonged to Class V socio-economic status. Majority (62%) of agricultural workers suffered from morbidities associated with oral cavity, followed by morbidities associated with musculoskeletal system (21.7%) and respiratory system (19%). Increasing age, gender and poor educational status were significantly associated with morbidities of oral cavity, musculoskeletal system, respiratory system, anaemia and animal bites. Conclusion: The present study suggests that, agricultural workers had a multitude of health problems. In order to overcome the situation, information, education and communication (IEC) activities needs to be strengthened and special health check-up camps to be conducted with emphasis on improvement of health.