Tuberculosis (TB) is a pulmonary disease caused by Mycobacterium tuberculosis. Various factors are associated with the transmission of TB including the infectiousness of the patient, duration of exposure and the nature of the environment, where exposure occurs. Tuberculosis diagnosis is the key concern of contemporary health research worldwide. TB control has been achieved in high-income countries but remained a threat for middle and low income countries. Transmission of TB can be reduced by fast diagnosis and complete treatment. Appropriate information of control policies and their adequate implementations are mandatory to achieve the desired results. Lack of awareness, inadequate treatment and fall in appropriate implementation on TB control and prevention programs are prevalent factors which become the barrier to achieve the TB elimination target.