One of the greatest blessings of God is health and according to religious teachings, the highest extent of health is human__ampersandsignrsquo;s spirit and heart health. Islam introduced the true meaning of health for humans and because human__ampersandsignrsquo;s life and living does not limit to worldly life, health considers in a broad context which humans reached to health and well-being in all facets of life by performing the religious sects and the need to acquire to this significant issue and the key for world__ampersandsignrsquo;s happiness is to recognize spirit and self. This study aims to explore the significance of human__ampersandsignrsquo;s spiritual and intellectual aspects, define heart and considers the health and disease according to the narratives and verses and finally indicate the effectiveness of heart__ampersandsignrsquo;s health on human body and introducing the spiritual dimensions.