Plants are the most important sources of medicines. Today the large number of drugs in use is derived from plants. The important advantages for therapeutic uses of medicinal plants in various ailments are their safety besides being economical, effective and easy availability. The present investigation was aimed to screen phytochemicals, antioxidant and antibacterial activities of ethanolic extracts of leaves of Aegle marmelos, Ocimum sanctum, Alternanthera sessilis, Eclipta alba, and Acalypha indica. The phytochemical analysis revealed the presence of terpenoids, phenols, flavonoids, tannins, alkaloids, cardiac glycosides, and steroids in all the extracts. The antioxidant activity of the extracts was evaluated by DPPH, ABTS and reducing power assay. All the extracts showed significant antioxidant activity. The plant preparations were also screened individually for antibacterial activity against three selected bacterial sp by agar-well diffusion method. Results showed that all the extracts were effective against bacterial sp tested.