During routine dissection we observed an unusual origin of an arterial trunk from radial artery in the right upper limb in a 55 year old male cadaver. The arterial trunk gives rise to common interosseous artery which intend dividing into anterior and posterior interosseous arteries. Bifurcation of brachial artery into radial and ulnar arteries in the cubital fossa found normal but there was no communication between radial and ulnar arteries in the palm. We also observed superficial course of ulnar artery underlying the skin and fascia with absence of branches. The branching patterns of radial and ulnar arteries on the left upper limb are found normal. Anomalies in the origin and course of principal arteries are having practical importance for the radiologists and vascular surgeons.