Aim: The aim of this study was to determine the presence and concentration of mercury (Hg) and arsenic (As) in organs and tissues of slaughtered pigs in Nsukka slaughter house. Methodology: From a total of 110 slaughtered pigs, liver, kidney and muscle samples of each pig were collected and analyzed for the detection of mercury and arsenic residue using Atomic Absorption Spectrophotometer. Results: A prevalence rate of 66.4% and 29.1% were recorded for mercury and arsenic respectively. The level of mean concentrations of arsenic in kidney, liver and muscle were 0.0016mg/kg, 0.0025mg/kg and 0.0012mg/kg respectively. While level of mean concentrations of mercury were 0.0009mg/kg, 0.0010mg/kg and 0.0006mg/kg in kidney, liver and muscle respectively. There was a significant difference (P__ampersandsignlt; 0.05) in the concentration of arsenic and mercury in liver, kidney and muscle samples of the different age groups of the slaughtered pigs. Conclusion: The levels of mercury and arsenic in few samples that exceeded the provisional tolerable weekly intake (PTWI) may pose human health threat to pork consumers in the study area.