Daphnia is the potential live feed available in small ponds and lakes. The present study is to evaluate the effect of the Daphnia magna enriched with different micro algae such as Spirulina platensis, Chlorella vulgaris and Spirogyra maximus on growth, survival and biochemical changes of freshwater fish Catla catla. The experimental fishes were fed with Spirulina enriched Daphnia (E1), Chlorella enriched Daphnia (E2), Spirogyra enriched Daphnia (E3), and unenriched Daphnia (E4) as a control and triplicates were maintained for each treatments. After 60 days, the growth rate, survival and Biochemical Compositions such as Protein, Lipids, carbohydrate, amino acids and fatty acids levels were measured. The highest survival rate was recorded as 99.17 % which corresponds to the highest growth rate of fish. Significant differences were observed (P __ampersandsignlt; 0.05) in weight gain, Specific growth rate (SGR), Food conversion ratio (FCR) and Survival (%) (E1) between experimental and control groups. The fishes were fed with diet E1 (S.platensis) was highly significant (P__ampersandsignlt; 0.05) with mean length (1.5 ?0.18 to 4.38 ?0.13) and mean weight (0. 0.210 ?0.01to 2.75 ?0.30) increase in weight gain 273.65% when compared to control (E4) fed fishes. The growth was estimated based on increase in biomass (1.91 + .007) and specific growth rate (3.12 __ampersandsignplusmn; 0.06). The Protein, Lipid and Carbohydrates were high in S.platensis enriched D.magna fed fishes. Hence we conclude that S.platensis enriched D.magna is a better food for the larval rearing of Commercial fish C. catla.