Background:- Substance abuse among children has become a major public health problem which has assumed alarming dimensions. They cause enormous human suffering in terms of morbidity, mortality and economic loss; threaten the very social fabric of almost all families, communities and nations around the world. Among young people children are the most vulnerable group as the initiation into substance abuse first starts during this period. Aims and Objectives:- To find out the socio-demographic factors associated with substance abuse. Material and Methods:- A descriptive cross-sectional survey was conducted among students (13-19 years) studying in classes 7th-12th in rural and urban areas of district Ambala, using the Self-Administered WHO Model Core Questionnaire. Stratified random sampling technique was used to select the respondents. A total of 1500 students studying in various government and private schools were taken for the study purpose. Results:- A significant impact of substance abuse was seen among male urban students (17-19 years) belonging to nuclear families and of middle socioeconomic class (SE-III). Parental physical/mental abuse, parental/friends drug abuse, family discoid, bad relationship with parents/teachers, were the triggering factors associated with substance abuse (p