Background: The biomedical waste generated from various sources has become a problem and much attention is being given worldwide to find a solution to this issue. Categorization, handling and management of biomedical wastes needs prime attention. Methods: Retrospective study. This study was conducted in the orthopaedics department of Coimbatore Medical College Hospital, Coimbatore.Data analysis of the wastes generated from 2010 to 2012 was done and the amount of wastes in each color category analyzed and compared for the given time interval. Results: The study revealed that the biomedical waste generated was 1045.85 kg in 2010, 827.35 kg in 2011 and 787.87kg in 2012 thus showing a gradual decline. The majority of the wastes were from the red bin during the study period when compared to the red bin and blue bin. This reduction in Bio medical waste was due to proper segregation of the wastes. Conclusion: Awareness about proper Bio medical waste (BMW) management has led to progressive reduction in the amount of wastes generated. Effective segregation of BMW is the need of time to complete the mission of eradicating diseases.