Introduction : The vertebral arteries begin in the root of the neck as the first branches from the supero-posterior aspect of the subclavian arteries. The vertebral arteries ascend the neck to enter the cranial cavity to supply blood to the brain. The two vertebral arteries are usually unequal in size; the left isfrequently larger than right one. Case Report: During an anatomy dissection, an anatomical variation of the origin of the left vertebral artery was observed in a 77-year-old male cadaver. . The aortic arch was giving origin to the left vertebral artery (6 mm in diameter), which was located between the origins of the left common carotid and left subclavian arteries. No other congenital variations were found. The left vertebral artery in our case enters the third cervical foramen transversarium. Conclusion : The anatomic and morphologic variations of the left vertebral artery are significant for diagnostic and surgical procedures in the head and neck region. It is of clinical importance to know the origin and course of prevertebral segment of the vertebral artery in detail and being aware of the possible variations to prevent complications.