Introduction: - Catheter associated urinary tract infections are common nosocomial infections, 80% cases of UTI are due to use of catheters. The incidence of becteriuria in catheterized patient is directly related to the duration of catheterization. E.coli, Proteus, Pseudomonas, Klebsiella, Serratia, Staphylococcus, Enterococci and Candida Sp. Are the common micro-organisms causing this infection? Aims and Objective: - The present study is to determine the microbiological profile and the sensitivity pattern which can cause Catheter Associated Urinary Tract Infections. Materials and Method: - The study was conducted in 100 adult patients, whom an indwelling Foley__ampersandsignrsquo;s catheter was inserted in AVBR Hospital during August 2011 to August 2012, in different medical wards, surgery wards and ICU. The catheterized urine sample was collected after catheterization on 5th day onwards on indwelling catheterization. Approximately 3 ml of urine was taken in sterilized container with the sterile precautions. The urine sample microscopy for pus cells, other abnormalities, gram staining was done and inoculate urine in culture medium. The final reading was done after 18 to 24 hrs. Of incubation of culture plates at 37oC. Antibiogram testing was done by Kirby-Bauer disk diffusion technique. Result and Conclusion :- The most common organism colonizing and causing catheter associated urinary tract infection as per observation were found to be E.Coli (57%) followed by Klebsiella Sp.(20%), Staphylococcus (8%), Enterococcus Sp. (6%), Pseudomonas aeruginosa (5%) and Acinetobacter Sp. (4%). Frequent cleanliness of catheter, area to avoid contamination and colonization of microbial flora, it is recommended to change the catheter every 5th day.