Objective: We retrospectively evaluated anatomic variants and anomalies of coronary arteries and found their incidence in 106 patients with the help of the 64-slice Computed Tomography Angiography (CTA). Materials and Methods: CT data of 106 patients who underwent 64-slice CT angiography (CTA) because of screening or suspected coronary artery disease were retrospectively reviewed in Department of Radiology, Geetanjali Medical College and Hospital, Udaipur. In each case, anatomic variants and anomalies were investigated. Results: The coronary artery system was right dominant in 85%, left dominant in 12% and co-dominant in 2.8 % of the cases. Ramus intermedius was present in 16.9%. Conus artery from Right coronary artery found in 72.6%, with a same ostium was observed in 10.3 % and in 16.9 % conus arteries originating with separate ostia were visualized. The sinus node artery (SNA) originated from the right coronary artery (RCA) in 66.9% and from the Left Circumflex artery (Cx) in 33%. LMCA was absent in 0.9%. Myocardial bridging was observed in 11.3%. Conclusion: Complex anatomy of the coronary artery tree can precisely be showed by 64-slice CTA. This technology is an appropriate substitute to conventional coronary angiography in distinguishing coronary artery variations and anomalies.