An Unilateral variation in the branching pattern of third part of axillary artery was observed on the left upper extremity of a 52 years old embalmed cadaver, during routine dissection for medical undergraduate students. In the present study we observed high origin of brachial artery and a common arterial trunk from the third part of axillary artery. The common arterial trunk gave rise to subscapular, profunda brachii, and common circumflex humeral arteries. The subscapular artery divided into thoracodarsal and circumflex scapular arteries. The common circumflex humeral artery gave rise to anterior circumflex humeral and posterior circumflex humeral arteries. On the right upper extremity branching pattern of third part of axillary artery was normal. Arterial anomalies in upper limb are important for surgeons and anaesthesiologists for reparative surgery and angiography.