The pharmaceutical industry is one of the major industries of Andhra Pradesh. Huge number of women were employed in these industries to carry out packing activities manually. These packing activities being static and repetitive may give rise to fixed body positions, continued repetition of movements and concentrated force on hand or wrist with out sufficient recovery between the movements. A study was undertaken to determine the prevalence of musculoskeletal symptoms among women workers involved in packing activities of pharmaceutical industry. The sample consisted of 270 women workers randomly selected from nine pharmaceutical industries in Hyderabad. Work posture was evaluated by using RULA (Rapid Upper Limb Assessment) technique. A scale was developed to study the musculoskeletal symptoms in nine anatomical body regions. The musculoskeletal discomforts like pain, stiffness, swelling, spasms and so on experienced by women were explored. Correlation between the postural score obtained with the use of RULA and musculoskeletal symptoms was explored. There was a significant positive correlation between RULA posture score and prevalence of musculoskeletal symptoms. Further through ANOVA significant difference between the respondents with mild, moderate and severe musculoskeletal symptoms was found out. The results emphasized poor working postures of the workers in packing activities need to be changed soon.