Chlorhexidine is a broad-spectrum antiseptic. It is recognized as Gold standard against which other antiplaque and antigingivitis agents are being compared. We are using it on medical devices and for skin preparation prior to procedures. It is well tolerated by patients and is a true life-saver in terms of prevention of infection and __ampersandsignldquo;multi-drug resistant organisms__ampersandsignrdquo;. Hence it can be called as a __ampersandsignldquo;Miracle Chemical__ampersandsignrdquo;. This article clearly suggests the properties and limitations of this miracle molecule __ampersandsignldquo;Chlorhexidine__ampersandsignrdquo; ensuring the maximum efficacy and the minimum side effects of the agent. Thus, this is one unique chemical which is considered as the past, present and future agent in the ever-growing field of clinical periodontics.