Introduction: Adolescent females are a major needy group. It is critical period of biological, psychological, and social changes, as achievement of optimum growth in girls is considered utmost, improving future health. Purpose: 1) to study physical and physiological changes in adolescent girls, with respect to secondary sexual characters of adolescent girls of Urban Health Center, Govt. Medical College Solapur. 2) To study some sociodemographic characteristics of the same. Methodology: A community based cross-sectional study was done involving 246 adolescent girls (116 nonslum and 130 slum) of Urban Health Center,Solapur.By doing house to house survey, adolescent girls were interviewed with the help of predesigned, pretested questionnaire. Their physical examination was done and secondary sexual characteristics assessed with strict privacy and confidentiality. Menstrual history was also taken. Results: Literacy was more among nonslum adolescent girls. Extended families were more in nonslum area. Family members were more in families of slum girls. There was significant difference between the socioeconomic status of nonslum and slum girls.The mean age of menarche was less in nonslum area than slum area. Also, there was significant difference at I, IV and V stages of SMR between nonslum and slum adolescent girls. Conclusions: There was significant difference in mean age at menarche and sexual maturity between adolescent nonslum and slum girls. Nutritional supplementation should be given to adolescent slum girls to improve their reproductive health.