Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411722EnglishN2025November29Healthcare Post MI Chordae Tendinae Rupture Diagnosis Using Blender 3D Assisted Frame-Rate Control and an Overview of Myocardial Ruptures” - A Case Report     English0104Chandra Shekara Reddy G.B.English Arun SrinivasEnglish Guruprasad H.P.English Introduction: Post–myocardial infarction (MI) mechanical complications remain catastrophic and require early detection. Con ventional 2D echocardiography may be limited in tachycardic or critically ill patients due to inadequate frame rates. Case Report: A middle-aged man aged 55-year-old with hypertension, hypothyroidism, and prior above-knee amputation pre sented with NSTEMI, evidenced by ST depression in V2–V6 and elevated Troponin I. Initial 2D echocardiography was normal. Coronary angiography showed single-vessel LAD disease with branch involvement, and OCT-guided PCI with two drug-eluting stents and a drug-eluting balloon was successfully performed. Despite initial stability, he developed sudden pulmonary edema, cardiogenic shock, and a new pansystolic murmur, suggesting a post-MI mechanical complication. Persistent tachycardia hin dered adequate echocardiographic visualization. A novel “Frame Rate Control’’ technique using Blender 3D software was applied to generate high-quality slow-motion reconstructions of the echo loops, enabling clearer assessment. This technique confirmed ruptured chordae tendineae with severe mitral regurgitation. Results: The patient’s respiratory failure progressed from oxygen therapy to BiPAP and ultimately mechanical ventilation. Emer gency high-risk mitral valve replacement was undertaken, but he could not be weaned from cardiopulmonary bypass and re quired massive transfusion due to recent antiplatelet and anticoagulant therapy. He died on postoperative day one. Discussion: This case underscores the need for prompt detection of post-MI mechanical complications and demonstrates the first documented clinical use of Blender 3D software to optimize echocardiographic frame-rate limitations. Such techniques may aid diagnosis when conventional imaging is inadequate, especially in hemodynamically unstable patients. EnglishMechanical Complication of MI, Cardiogenic Shock, Cardiac Catastrophy, Chordae Tendinae Rupture, Blender 3D Software, Frame Rate Controlhttp://ijcrr.com/abstract.php?article_id=4879http://ijcrr.com/article_html.php?did=4879 1. Dal-Bianco JP, Levine RA. Anatomy of the mitral valve appa ratus–role of 2D and 3D echocardiography. Cardiol Clin. 2013 Apr 15; 31(2):10-16. 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Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411722EnglishN2025November29Healthcare A Study on Marketing Strategies Used by Alkem Laboratories for Brand Building of Pan-D Antacid Tablet     English0508Krishna KadamEnglish Suryakant ChavanEnglish Shilpa PiseEnglish Aim: The aim of the study is to analyze the marketing strategies adopted by Alkem Laboratories for brand building of PAN-D antacid tablet in the gastrointestinal segment and to understand the role of medical representatives, doctors, and pharmacists in influencing brand perception and prescription behavior. Methodology: The study is based on both primary and secondary data. Primary data were collected from 120 respondents in Pune, including doctors, pharmacists, and medical representatives, using structured questionnaires and personal interviews. Secondary data were obtained from company reports, journals, websites, and published research. The collected data were ana lyzed using percentage analysis to identify key factors influencing brand building and prescription loyalty. Results: The findings of the study indicate that regular visits by medical representatives (96%), Continuing Medical Education (CME) programs (84%), and availability of clinical evidence (83%) play a major role in strengthening PAN-D’s brand image among doctors. Pharmacists’ stocking decisions are largely influenced by doctor demand (80%) and company reputation (60%). The study also identifies challenges such as price competition, limited promotional budgets, and intense market competition as significant barriers to the adoption of new pharmaceutical brands. Conclusion: The study concludes that Alkem Laboratories has successfully built a strong brand image for PAN-D through consistent field engagement, effective medical representative interactions, and ethical, science-based promotion. Continuous doctor education, strong company reputation, and relationship marketing have significantly contributed to sustained prescription loyalty. In a highly competitive pharmaceutical market, maintaining ethical promotion practices and scientific validation remains essential for long-term brand leadership. EnglishPAN-D antacid, Alkem laboratories, Brand image, Marketing strategies, Pharmaceutical brands, Science based promotion, Ethical promotion practices, Market competitionhttp://ijcrr.com/abstract.php?article_id=4883http://ijcrr.com/article_html.php?did=4883 1. Kotler, P., & Keller, K. L. (2022). Marketing management (16th ed.). Pearson Education. 2. Alkem Laboratories Ltd. (2024). Company profile and annual report. 3. Indian Pharmaceutical Alliance (IPA). (2023). Annual report on the Indian pharmaceutical market. New Delhi: IPA Publications. 4. Mehta, A., & Sharma, V. (2023). Impact of medical representa tive activities on doctor prescription behavior. Indian Journal of Pharmaceutical Marketing, 15(2), 45–52. 5. Gupta, R., & Patel, S. (2022). Marketing trends and brand building strategies in the Indian pharmaceutical sector. Journal of Healthcare Marketing Research, 10(1), 25–38. 6. World Health Organization (WHO). (2023). Ethical criteria for medicinal drug promotion. Geneva: WHO Press. 7. Singh, P., & Deshmukh, K. (2021). The role of continuing medi cal education (CME) in influencing doctor prescription patterns. Asian Journal of Pharmaceutical and Clinical Research, 14(3), 112–118.