Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411719EnglishN2025October15Healthcare Comparison of Malaria Prevalence and Risk Factors in Urban and Rural Areas of Forest Guinea     English0105Joseph Fara KoumassadounoEnglish Nadege Adouk AgbodjatoEnglish Michel Mathurin KamdemEnglish Mamadou Samba BarryEnglish Mamadou Cellou BaldeEnglish Introduction: Malaria is a major public health problem in sub-Saharan Africa. In Guinea, the disease is widespread throughout the country, particularly in the forest region where it is endemic. The objective of this study was to assess the prevalence of malaria in urban and rural areas of Guinea’s forest region by identifying potential socio-economic factors associated with the onset of the disease. Method: Blood samples of 280 patients suffering from malaria (102 and 178 patients in urban and rural areas, respectively) were collected between early May and late August 2022 across healthcare facilities of the forest Guinea, and analysed in the labora tory of the International Centre for Research on Tropical Infections of Guinea (CIRIT-Guinea) for the presence of Plasmodium using the loop-mediated isothermal amplification (LAMP) technique. A questionnaire was used to record information on socio demographic characteristics of patients such as age, gender, place of residence and occupation. Results: Results showed that 63.6% of malaria cases occurred in rural area, compared with 36.4% in urban area, although the difference was not statistically significant (p = 0.12). This could indicate widespread endemicity of the disease in the region. The absence of any significant difference in the distribution of patients by age group (p = 0.76) and gender (p = 0.47) indicates that control strategies should be comprehensive, without prioritizing certain demographic groups. In terms of occupation, malaria was overrepresented among farmers in rural areas (p = 0.03), probably reflecting ongoing exposure to mosquito breeding sites, particularly irrigated farms and stagnant water. Conclusion: These results highlight the need to develop differentiated approaches according to the people occupation. There is need to provide healthcare facilities with additional medical staff and laboratory equipment to ensure reliable diagnosis and to conduct door-to-door awareness campaigns in rural and urban communities on preventive measures against malaria. EnglishFarmers, Urban environment, Rural environment, Prevention, Awareness-raising, reliable diagnosishttp://ijcrr.com/abstract.php?article_id=4873http://ijcrr.com/article_html.php?did=4873 1. 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J Eth nopharmacol. 2013 Dec; 150(3): 1145-1153. 6. Doutoum AA, Doungous DM, Gondimo EG, Laougangta RD, Adoum A, Garandi B, et al. Prevalence and risk factors asso ciated with malaria in patients at Abéché Provincial Hospital (Chad). Int. J. Biol. Chem. Sci. 2019 Nov; 13(4): 1995-2004. 7. Kouassi A. Pharmaco-economic evaluation of artemisinin de rivative-based combination therapies for the treatment of un complicated malaria in the Ivory Coast, Pharmacy thesis, Ivory Coast. 2016, 161 pages. (N°: 1827-17, Ref: FT 1877). 8. Camara A. Guinean medicinal plants: validation of the antima larial effect and impact on the modulation of immunity. Immu nology. PhD thesis Université Paul Sabatier - Toulouse III; Uni versité Gamal Abdel Nasser in Conakry. 2020. French. ffNNT: 2020TOU30028f. 9. Ortiz DI, Piche-Ovares M, Romero-Vega LM, Wagman J, Troyo A. The Impact of Deforestation, Urbanization, and Changing Land Use Patterns on the Ecology of Mosquito and Tick-Borne Diseases in Central America. 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Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411719EnglishN2025October15Healthcare Respiratory Rehabilitation and Clinical Outcomes in AECOPD     English0610Shailaja V. PatelEnglish Krupa PatelEnglish Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a major global health burden, with acute exacerbations (AECOPD) leading to delayed recovery and higher morbidity despite optimal medical treatment. Aim/Objectives: To evaluate the effect of structured respiratory rehabilitation on dyspnea, cough severity, and exercise toler ance in hospitalized AECOPD patients. Methods: A prospective interventional study was conducted on 30 hospitalized AECOPD patients. Participants were divided into two groups: the experimental group received standard care plus respiratory rehabilitation (education, sputum clearance, pursed lip breathing, upper-limb exercises, and walking training), while the control group received standard care alone. Outcomes as sessed at baseline and after 4 days included dyspnea (mMRC), cough severity (VAS), exercise tolerance (6MWT), and sputum expectoration. Results: The experimental group showed significant improvements in dyspnea (p = 0.0052) and exercise tolerance (p = 0.0344) compared to controls. No significant differences were observed in cough severity or sputum clearance. Within-group analysis indicated greater improvement in dyspnea and functional capacity in the experimental group, while the control group improved only in exercise tolerance. Discussion/Conclusion: Early initiation of structured respiratory rehabilitation during hospitalization enhances recovery in AE COPD by reducing dyspnea and improving functional capacity, highlighting its value as an adjunct to standard medical care. EnglishCOPD, AECOPD, respiratory rehabilitation, dyspnea, exercise tolerance, hospitalizationhttp://ijcrr.com/abstract.php?article_id=4874http://ijcrr.com/article_html.php?did=4874 1. 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Effect of airway clearance tech niques in patients experiencing an acute exacerbation of chronic obstructive pulmonary disease: a systematic review. Chron Respir Dis. 2010;7(1):9-17. 20. Kodric M, Garuti G, Colomban M, Lusuardi M, Donner CF, Clini EM. The effectiveness of a bronchial drainage technique (ELT GOL) in COPD exacerbations. Respirology. 2009;14(3):424-8. 21. Seymour JM, Moore L, Jolley CJ, Ward K, Creasey J, Steier J, et al. Outpatient pulmonary rehabilitation following acute exac erbations of COPD. Thorax. 2010;65(5):423-8. 22. Clini EM, Crisafulli E, Costi S, Fabbri LM, Ambrosino N. Ef fects of early inpatient rehabilitation after acute exacerbation of COPD. Respir Med. 2009;103(10):1526-31. 23. Lareau SC, Yawn BP. Improving adherence with inhaler therapy in COPD. Int J Chron Obstruct Pulmon Dis. 2010;5:401-6. 24. Nishimura K, Yasui M, Nishimura T, Oga T. Clinical pathway for acute exacerbations of chronic obstructive pulmonary dis ease: method development and five years of experience. Int J Chron Obstruct Pulmon Dis. 2011;6:365-72. 25. Sridhar M, Taylor R, Dawson S, Roberts NJ, Partridge MR. A nurse-led intermediate care package in patients who have been hospitalised with an acute exacerbation of chronic obstructive pulmonary disease. Thorax. 2008;63(3):194-200.