Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241175EnglishN2025March13Healthcare Message from Massage - An Uncommon Complication of Oral Anti Coagulants     English0103Chandra Shekara ReddyEnglish Arun SrinivasEnglish Siddarth Kumar ChawathEnglish Introduction: Individualized Anticoagulants are used for stroke prevention in Atrial Fibrillation (AF) and Venous Thrombo Embolism (VTE) prophylaxis. Case Report: We had a Forty-Two-year old male patient who was admitted with history of exertional breathing difficult. Also had pain, swelling and tenderness of bilateral anterior thigh region. Local Ultra Sound examination reported hematoma and hemarthrosis. He was on treatment for Type 2 DM, HTN, Paroxysmal AF and Post DVR (2016) and Redo MVR (2018) with Oral Anti Coagulation (OAC) along with other routine medications. These acute symptoms occurred following self-advised bilateral lower limb massage for myalgia. His preliminary investigation revealed Severe Anemia (Hb - 3.8gms/dl) and INR of > 10. Received 3 units of compatible blood transfusions, IV Vitamin K injections and other routine medications. Hb improved to 9.4 gms/dl. 2D Echocardiography although initially showed increased gradients across prosthetic valves improved after blood transfusions. Symptoms gradually stabilized and discharged with stable hemodynamic conditions. Discussion: Clinicians face increasingly complex decisions relating to appropriate agent, duration of treatment and use in special populations. Newer OACs, like Dabigatran (oral Factor Xa inhibitor) neither requires regular laboratory monitoring nor affected by external factors. EnglishInternational Normalised Ratio (INR), Oral Anti Coagulants (OAC), Stroke prevention, DVT Prophylaxis, VenousThrombo Embolism (VTE), Mechanical Valve Prosthesis, Non-Valvular Atrial Fibrillation (AF)http://ijcrr.com/abstract.php?article_id=4842http://ijcrr.com/article_html.php?did=4842 1. Chen A, Stecker E, A. Warden B. Direct oral anticoagulant use: a practical guide to common clinical challenges. J Am Heart Assoc. 2020 Jul 7; 9(13):e017559. 2. Helin T, Joutsi-Korhonen L, Lassila R. Clinical use and laboratory testing of oral anticoagulation therapy: experience from Finland. Ann Blood. 2019 Jul; 4:17. 3. Cannegieter SC, Rosendaal FR, Wintzen AR, Van der Meer FJ, Vandenbroucke JP, Briet E. Optimal oral anticoagulant therapy in patients with mechanical heart valves. N Engl J Med. 1995 Jul 6; 333(1):11-7. 4. Ma QH, Fang JH. International normalized ratio for the guidance of warfarin treatment in elderly patients after cardiac valve replacement. Exp Ther Med. 2019 Feb;17(2):1486-91. 5. El-Helou N, Al-Hajje A, Ajrouche R, Awada S, Rachidi S, Zein S et al. Adverse drug events associated with vitamin K antagonists: factors of therapeutic imbalance. Vasc Health Risk Manag. 2013 Mar 1:81-8.

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241175EnglishN2025March13Healthcare Does Physical Activity and Cell Phone Usage Affect Heart Rate Variability in Paramedic Students?     English0408Vishwa ThakerEnglish Drashti ShiroyaEnglish Hemanshi ShiroyaEnglish Mileni GodhaniEnglish Vaishali GabaniEnglish Introduction: Cardiovascular diseases (CVD) are a significant cause of morbidity and mortality. HRV, which reflects the modula- tory capacity of the autonomous nervous system, plays a crucial role in influencing mortality. Aims/Objectives: In this cross-sectional study, we investigate the impact of physical exercise and cell phone usage on HRV measures. The objective of this study is to find that physical activity and usage of cell phones influence heart rate variability in paramedical students. Method: A total of 94 paramedical students (70 females and 24 males) aged 18-25 (mean age 20.4±1.5) volunteered for this study. Physical activity and duration of the mobile usage were measured using International Physical Activity Questionnaire (IPAQ-short form) and structured questionnaire respectively. A 5-minute short-term HRV measurement was obtained by Kubios HRV smart phone application. Each participant was rested in supine for 10 minutes before the HRV measurement and was instructed to remain relaxed, breathe normally, avoid talking and sleep during the measurement. Time domain (SDNN, RMSSD) and frequency domain parameters (LF power, HF power, and LF/HF ratio) were measured for HRV analysis. Result: Study found no significant association between physical activity and smartphone usage with HRV measures in males and females. Conclusion: This study concludes that there is no correlation of physical activity and mobile phone usage on heart rate variabil- ity parameters. However, due to increased cell phone usage and low physical activity among college students, assessing these factors can assist to prevent future negative events and enhance health awareness. EnglishHRV, Physical activity, Paramedical students, Stress, IPAQ, Screen time, Mobile usagehttp://ijcrr.com/abstract.php?article_id=4844http://ijcrr.com/article_html.php?did=4844 1. Shaziya A. What Is Heart Rate Variability (HRV)? Normal, High, and Low. Cired from https://www.medicinenet.com/ what_is_heart_rate_variability_hrv/article.htm, access date: Jan 3, 2025 2. Tarvainen MP, Niskanen JP, Lipponen JA, Ranta-Aho PO, Karjalainen PA. Kubios HRV–heart rate variability analysis software. Comput Methods Programs Biomed. 2014 Jan 1; 113(1):210-20. 3. Soares-Miranda L, Sandercock G, Valente H, Vale S, Santos R, Mota J. Vigorous physical activity and vagal modulation in young adults. Eur J Cardiovasc Prev Rehabil. 2009 Dec 1; 16(6):705-11. 4. Rennie KL, Hemingway H, Kumari M, Brunner E, Malik M, Marmot M. Effects of moderate and vigorous physical activity on heart rate variability in a British study of civil servants. Am J Epidemiol. 2003 Jul 15; 158(2):135-43. 5. Feng QI, Zhang QL, Du Y, Ye YL, He QQ. Associations of physical activity, screen time with depression, anxiety and sleep quality among Chinese college freshmen. PLoS One. 2014 Jun 25;9(6):e100914. 6. Sanudo B, Fennell C, Sánchez-Oliver AJ. Objectively assessed physical activity, sedentary behaviour, smartphone use, and sleep patterns pre-and during-COVID-19 quarantine in young adults from Spain. Sustainability. 2020 Jul 22; 12(15):5890. 7. Lee PH, Macfarlane DJ, Lam TH, Stewart SM. Validity of the international physical activity questionnaire short form (IPAQ SF): A systematic review. Int J Behav Nutr Phys Act. 2011 Oct; 8:115 8. Vaishali G, Saravanan M. Reliability and Validity of Kubios HRV Smart Phone Application as Measures of Heart Rate Vari ability. International Journal of Current Research and Review (IJCRR). 2024; 16(6): 07-10. 9. Chen H, Xu J, Xie H, Huang Y, Shen X, Xu F. Effects of physi cal activity on heart rate variability in children and adolescents: a systematic review and meta-analysis. Cien Saude Colet. 2022 May 4; 27:1827-42. 10. Tamer A, Gunduz H, Ozy?ld?r?m S. The cardiac effects of a mo bile phone positioned closest to the heart. Anatol J Cardiol. 2009 Oct 1; 9(5):: 380-4.