Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411420EnglishN2022October17Healthcare
To Determine the Efficacy of Strontium Ranelate in the Healing of Surgically Fixed Tibial Diaphyseal Fractures Using Intramedullary Devices (Nails) in Tertiary Care Hospital
English0105Soomro SaifullahEnglish Soomro Zamir AEnglish Chandio M ShuaibEnglish
Introduction: Strontium ranelate is a strontium salt of ranelic acid that enhances bone healing by increasing the deposition of new bone-forming osteoblasts and reduces the function and number of bone-resorbing osteoclasts. Strontium ranelate acts via a dual mode of action with both bone-forming and bone-resorbing properties, and may therefore be beneficial in fracture healing. It is therefore promoted as a “dual-action bone agent. Objective: To determine the efficacy of strontium ranelate in the healing of surgically fixed tibial diaphyseal fractures using intramedullary devices (nails) in tertiary care hospital. Material and Methods: This descriptive case series study was done at the department of orthopedic surgery, Chandka medical college Larkana and was conducted for six months between 1st of July 2021 to 31st of December 2021. Total 184 patients with closed diaphyseal tibial fractures were included. All patients have undergone closed reduction and internal fixation using nail. Strontium ranelate as a single dose for a duration of three months was given. Final outcome i.e. efficacy was measured on the basis of clinical and radiological criteria. Descriptive statistics were calculated using SPSS. Stratification was done and the post-stratification chi-square test was applied. P-value ≤ 0.05 was taken as significant. Results: There were 118 were male and 66 were female. The mean age of study subjects was 34.18±9.80 years. The mean duration of fracture was 5.78±3.29 days. 49.5% were caused by fractures due to road traffic accidents. The efficacy of strontium ranelate was found in 67.9%. The significant association of efficacy of strontium ranelate was observed with age and duration of fracture. Conclusion: Significant efficacy of strontium ranelate in the healing of surgically fixed tibial diaphyseal fractures on clinical and radiological assessment was observed.
EnglishEfficacy, Strontium Ranelate, Fixed Tibial Diaphyseal Fractures, Nails, Bone healing, Radiological unionhttp://ijcrr.com/abstract.php?article_id=4614http://ijcrr.com/article_html.php?did=4614
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Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411420EnglishN2022October17Healthcare
Recent Findings on Alpinia Galanga (L.) Wild for the Treatment of Arthritis Part-1
English0610Roopam RautEnglish Jessy ShajiEnglish
Arthritic inflammation of joints affects people of all age groups. The treatment is a challenge as arthritis is a complex disease and evolves over years. Patients often have to take medicines for the rest of their life. Commonly prescribed medicines like analgesics, glucocorticoids and non-steroidal anti-inflammatory drugs have side effects. The new disease-modifying medicines are costly. People in the healthcare system are assessing the dynamics of complementary and alternative medicines. One such remedy is Alpinia galanga (AG) of Zingiberaceae family. It is characterized by the presence of rhizome, wide leaves and terminal inflorescence. The references for its medicinal uses are found in traditional medicines. It is cultivated in tropical regions of south east Asia. Its rhizome is highly aromatic and most frequently used as a food and medicine. The various extracts of AG are prepared by the researchers and studied for its phytoconstituents and pharmacological activities. Clinical, in vitro, in vivo and in silico experimentation techniques are used to validate the claims for various therapeutic activities. This article focuses on reviewing the literature to ascertain the anti-arthritic potential of AG. The article has been divided in 2 parts and includes analgesic, anti-arthritic, anti-inflammatory, antioxidant, other therapeutic effects as well as safety and toxicity of AG.
EnglishGreater galangal, Ginger, Antioxidant, Anti-inflammatory, Analgesic, Rheumatic, Rhizome.http://ijcrr.com/abstract.php?article_id=4615http://ijcrr.com/article_html.php?did=4615Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411420EnglishN2022October17Healthcare
Recent Findings on Alpinia Galanga (L.) Wild for the Treatment of Arthritis Part-2
English1116Roopam RautEnglish Jessy ShajiEnglish
Arthritic inflammation of joints affects people of all age groups. The treatment is a challenge as arthritis is a complex disease and evolves over years. Patients often have to take medicines for the rest of their life. Commonly prescribed medicines like analgesic, glucocorticoids and non-steroidal anti-inflammatory drugs have side effects. The new disease-modifying medicines are costly. People in the healthcare system are assessing the dynamics of complementary and alternative medicines. One such remedy is Alpinia galanga (AG) of Zingiberaceae family. It is characterized by the presence of rhizome, wide leaves and terminal inflorescence. The references for its medicinal uses are found in traditional medicines. It is cultivated in tropical regions of south east Asia. Its rhizome is highly aromatic and most frequently used as a food and medicine. The various extracts of AG are prepared by the researchers and studied for its phytoconstituents and pharmacological activities. Clinical, in vitro, in vivo and in silico experimentation techniques are used to validate the claims for various therapeutic activities. This article focuses on reviewing literature to ascertain the anti-arthritic potential of AG. The article has been divided in 2 parts and includes analgesic, anti-arthritic, anti-inflammatory, antioxidant, other therapeutic effects as well as safety and toxicity of AG.
EnglishGreater galangal, Ginger, Antioxidant, Anti-inflammatory, Analgesic, Rheumatic, Rhizome.http://ijcrr.com/abstract.php?article_id=4616http://ijcrr.com/article_html.php?did=4616Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411420EnglishN2022October17Healthcare
Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward
English1725Alice AliceEnglish
Mother’s milk is widely recognized as an exclusive source of nutrients, particularly for premature infants. However, there are situations when mother’s own milk is inaccessible to newborns, in such cases, expressed milk from donor mothers is essential to cover the gaps. Human Milk Banks (HMBs) have been developed in several regions of the world to address such difficulties. Despite the fact that there are multiple active HMBs across the globe, there is a lack of comprehensive data on the relevance and operation of human milk banks across South Asian Countries (SACs) where the burden of infant death due to prematurity remains disproportionately high. Challenges like lack of technological facilities, funding channels and universal guidelines impede its full potential. Additional challenges include cultural beliefs, taboos, lack of awareness and knowledge also exacerbate such conditions. Therefore, there is an urgent need to comprehend the formation of universal guidelines and the recruitment of technical leaders for optimizing and promoting HMBs for fulfilling the needs of newborns. This review article addresses these issues in depth and discusses potential solutions to overcome such gaps.
EnglishHuman Milk Banking, New-born, Premature infants, Donor Human Milk, Lactational Management Unit, South Asian Countrieshttp://ijcrr.com/abstract.php?article_id=4617http://ijcrr.com/article_html.php?did=4617Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411420EnglishN2022October17Healthcare
Effectiveness of anti-smoking Program among Adolescence at Community-Based School Karachi-Pakistan
English2630Sohail SajidEnglish Shireen ArifEnglish Alia NasirEnglish Shahzad BashirEnglish AroojEnglish Iram AminEnglish
Introduction: Tobacco smoking is one of the alarming phenomena in different societies which leads different health problems among people day by day. The study aims to evaluate the effectiveness of a prevention program of smoking at a community-based school of Bhittaiabad at Karachi-Pakistan. Methods: The quasi-experimental study conducted at a community-based school of Bhittaiabad Karachi from June to December 2018. Data were collected via, structured questionnaires from 200 secondary school children through consecutive sampling technique studying in grade 8th, 9th and 10th. The validity and reliability of the questionnaire was established thoroughly. Participants were approached after signing consent forms both parents. Questionnaires were filled one-week prior of the intervention period. Post-test conducted after fifteen days of the intervention. The intervention period consist of (82) eighty-two hours. Results: In this study, 200 students showed that their level of knowledge increased after the intervention period however, the p-value shows an insignificant result. Moreover, the smoking-related attitude has been significantly observed after an intervention (p-value EnglishEffectiveness, Prevention, Tobacco Smoking, Adolescence, Community-Based School, Karachi-Pakistanhttp://ijcrr.com/abstract.php?article_id=4618http://ijcrr.com/article_html.php?did=4618
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