Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20Life SciencesBioremediation Potential of Plant Growth Promoting Rhizobacteria (PGPR) to Promote Zeamays L. growth under Petrol Stress English0108Habib SEnglish Ahmed AEnglishEnglishBioremediation, Biosurfactants, Emulsification, Hydrocarbon, PGPR, Zea mays Lhttp://ijcrr.com/abstract.php?article_id=4484http://ijcrr.com/article_html.php?did=4484

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareHypertension Among General Population Visiting at South East Hospital and Research Center, Islamabad, Pakistan English0914Mehmood AtherEnglish Attiya Hameed KhanEnglish Ali Akhtar BandeshahEnglish Hussain WajidEnglish Shah AdnanEnglish Abdul Samad AbbasiEnglishEnglishHypertension, Risk factor, Diabetic Mellitus, Incidence, World Health Organization, Epidemiology, Awareness, Assessmenthttp://ijcrr.com/abstract.php?article_id=4485http://ijcrr.com/article_html.php?did=4485

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareEffect of the Repeated Sprint Ability Test on Lung and Musclefunction and Recovery Kinetics in Young Soccer Players English1522Boussana AlainEnglish Nsompi FlorentEnglish Moukouyou Antoine EricEnglish Candau RobinEnglishIntroduction. High-intensity and long distances exercises have been shown to induce alterations in lung and peripheral muscle function. Nevertheless, alterations and recovery periods have not been studied in response to the repeated sprint ability (RSA) test (6×35m). Aim: The purpose of this study was to evaluate the effect of a repeated sprint ability (RSA) test on lung function and lower limb power in young soccer players. Method: Twelve young male soccer players (20.1 ± 1.8 years old) performed a repeated sprint ability (RSA) test (6×35m). Spirometric parameters, countermovement jump (CMJ) height, lower limb power, and heart rate (HR) were assessed before the test, immediately after the test, and 3, 6 and 9 minutes post-test. Spirometric parameters were measured in the sitting position with a portable Spirobank G. Countermovement jump height and lower limb power were assessed with a Myotest during the countermovement jump and the fatigue index percentage (%FI) was calculated. Results: Immediately after the repeated sprint ability (RSA) test, significant decreases (P< 0.02, P< 0.009 respectively) were observed in forced vital capacity (FVC) and peak expiratory flow rate (PEFR). Lower limb power during the countermovement jump was significantly reduced immediately after exercise (P< 0.001) and was significantly increased at 3 minutes post-RSA. During the repeated sprint ability test, fatigue index percentage (%FI) was significantly high (32.3%). Conclusion: The repeated sprint ability test induced a decrease in lung function, suggesting airway closure. The muscle power of the lower limbs decreased concomitantly with an increase in fatigue index percentage, suggesting muscle fatigue. However, the alteration in lung and peripheral muscle function was not persistent as these soccer players quickly recovered these functions 3-6 minutes after the repeated sprint ability test, suggesting mild and transient mechanisms. EnglishRunning speed, Change of direction, Repeated effort, Pulmonary function, Athletic training, Muscle fatiguehttp://ijcrr.com/abstract.php?article_id=4486http://ijcrr.com/article_html.php?did=4486

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareAssessment of Knowledge, Attitude, Practice and Safe Disposal of Biomedical Waste: The Darker Side of Healthcare English2331Mboka Olonu Marie ThereseEnglish Gurdeep SinghEnglish Udeh Blessing NnennaEnglish Mukesh Kr. SinghEnglish Ritesh PatelEnglishMedical waste operation is one of the numerous complex and demanding challenges facing humanity as the global population swells and the demand for medical services increases. A medical waste product in the developing world is rising quickly due to bettered access to medical services which allow ever lesser figures of admit modern medical care. Contradictory methods of waste measurement used by researchers leave these variations questionable. The objective of biomedical waste management (BMW) operation generally involves preventing diffusion of illness from patient to medical expert to forestall injury to the health care employee and staff in support services, whereas handling medicine waste, to forestall general exposure to the harmful effects of the cytotoxic, geotaxis and chemical drug waste generated in hospitals. The main objectives of this paper were to analyze the status of medical waste generation and treatment in recent years, and also address the discussion on waste risks and the impact on health and the environment. The study indicates that greater training for healthcare personnel and standardizing the categorization of medical waste streams are important steps toward more efficient waste management in hospitals. EnglishBiomedical waste management, Cytotoxic, Environment, Healthcare, Waste treatment, Geotaxishttp://ijcrr.com/abstract.php?article_id=4487http://ijcrr.com/article_html.php?did=4487

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareAcute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents English3241Pandya S.English Savaliya C.English Thummar K.English Undale V.EnglishIntroduction: Ayurvedic medications are extensively used across the world for illness prevention and treatment. The components found in the Coroprotect tablet are Ashwagandha ext., Suddhashilajit ext., Giloyext., Dadim ext., Haridra ext., Saragavo ext., Brahmi ext., Papaya ext., Methiext., Punarnava ext., Kalmegh ext. etc. all are found to be safe and used in Ayurvedic system for many years. Objective: In Rodents, acute and subacute toxicity of coroprotect tablet was studied after a single and repeated 28-day oral dosage administration. Method: In acute toxicity testing, 2000 mg/kg single dose of coroprotect tablet have been employed, whereas doses of 100, 200, and 400mg/kg have been utilized in subacute toxicity testing over a 28-day period in rodents. Result: With coroprotect tablet administration, no treatment-related fatalities or toxic signs have been identified in an acute toxicity investigation. There have been no significant variations in body weight changes, water/food intake, haematology, or clinical biochemistry content among the control and coroprotect tablet groups in the repeated dosage research. Between the control and coroprotect pill groups, no gross pathological abnormalities or differences in relative organ weights were found. With coroprotect tablet therapy, the histopathological investigation indicated no abnormalities. Conclusion: In a repeated dosage toxicity study in rodents, the coroprotect tablet was determined to be safe at all dose levels. EnglishCoroprotect tablet, Acute toxicity, 28-Day Repeated Dose toxicity, Subacute Toxicity, Wistar rat, Ayurvedic supplementhttp://ijcrr.com/abstract.php?article_id=4488http://ijcrr.com/article_html.php?did=4488

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareStudy of L-Asparaginase from Marine Fungi and its Potential as an Anti-cancer Agent: A Preliminary Study using Chorioallantoic Membrane Assay English4349Gaonkar AmrinEnglish Malik N.N.English Yadav MamtaEnglish Nair Santhini SEnglish Patil ShwetaEnglishIntroduction: L-asparaginase is a therapeutic enzyme that is used in combination therapy for mainly Acute Lymphocytic Leukemia (ALL) and other cancers. It hydrolyzes L-Asparagine required by neoplastic cells into L-aspartate and ammonia which leads to the death of tumor cells. But commercially available L-asparaginases show fatal side effects because of its prokaryotic source of origin, and associated glutaminase and urease co-activities. Aims: Screening of marine fungi for L- asparaginase activity and study of its potential as an anti-cancer agent. Methodology: This study was designed to isolate fungi from marine water and soil samples collected from regions of Maharashtra and Goa, that are capable of producing L-asparaginase enzymes that are free of urease and glutaminase activity, and further study the potential of anticancer activity of these eucaryotic enzymes using Chorioallantoic membrane (CAM) assay. Result: Among all twelve marine fungi isolated, RF2 (identified as Aspergillusaculeatus (Genbank accession no.ON023823)) from Mandvi beach, Ratnagiri MH demonstrated high levels of L-asparaginase activity within 48-96 hrs, while lacking glutaminase and urease activity. Conclusion: The Chorioallantoic membrane (CAM) assay revealed that this fungal isolate could be a promising source of eucaryotic L-asparaginase to treat cancer with lower side effects. EnglishAnti-cancer, Chorioallantoic membrane assay, Eucaryotic, glutaminase, L-asparaginase, Ureasehttp://ijcrr.com/abstract.php?article_id=4489http://ijcrr.com/article_html.php?did=4489

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcarePsychometric properties of the Quality-of-Life Questionnaires (SF-36), (MLHFQ) Minnesota Living with Heart Failure Questionnaire among Congestive Heart Failure Patients English5054Shaheen NazakatEnglish Kabir Ozigi AbdullahiEnglish Adnan YaqoobEnglish Muhammad SajidEnglishIntroduction: The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is one of the most extensively used heart failure patient quality of life questionnaires (HF). It includes physical and emotional scores, as well as a total score. However, its factor structure has been questioned, and alternatives proposed, including a third factor expressing a social dimension. This Survey used to monitor population health, assess treatment outcomes, and estimate illness burden. Aims: Validation and testing of the SF-36 Quality of Life Questionnaire (QOLQ) and the Minnesota Living with Heart Failure Questionnaire (MLHFQ) were the main objectives of this work in CHF patients. To identify the psychometric properties of the quality-of-life questionnaires (SF-36) and MLHFQ questionnaire among congestive heart failure patients Methodology: The quasi-experimental study was conducted in those individuals who has suffered from heart failure (n= 36). These patients were admitted at the FIC, Faisalabad. The teach-back technique was introduced to teach about self-care to improve the QOL of the participants. Every participant was administered the SF-36 and MLHFQ after intervention Post-test -1 was conducted at 30 days after accomplishment of the intervention with a filling of both tools collected by the researcher/ facilitator on a one-month clinical follow-up visit. Posttest-2 was conducted at 90 days after intervention at each participant on a three-month follow-up visit. Results: The researcher evaluated the questionnaire's psychometric parameters, as well as the extent to which one may rely on the accuracy of a measurement, computation, or specification. (Internal consistency, test-retest analysis, and inter-item correlation). Exploratory factor analysis was used to determine the construct validity. Conclusion: It is found that the Urdu version of the Questionnaires (SF-36) and the MLHFQ questionnaire were proven to be a trustworthy and valid tools for improving the quality of life in patients with congestive heart failure. With the use of these versions of the scale, assessing patient QOL, performance, has become smoother and readmission frequency in congestive heart failure Patients would become lesser. EnglishPsychometric Properties, SF-36, MLHFQ, Congestive Heart Failure Patients, QOL, Cronbach’s alphahttp://ijcrr.com/abstract.php?article_id=4490http://ijcrr.com/article_html.php?did=4490

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareThe Art of Seeing the Invisible: CBCT & Missed Canals English5558Munish SinglaEnglish Harleen KaurEnglish Litik MittalEnglish Savrose KaurEnglishRadiographic imaging is a primary and most essential step in the diagnosis, treatment planning and assessing the treatment outcomes of all the cases in endodontics. There are several confounding factors like regional anatomy and superimposition of the teeth and adjacent dentoalveolar structures that influence the interpretation of an image. Due to the complex maxillofacial skeleton, conventional two-dimensional (2-D) radiographic images fail to provide accurate information. The structures so visualized are also subject to geometric distortion. Since untreated anatomy has been documented as a significant cause of endodontic failure. Hence, recent research has highlighted the need for 3-D imaging modality to be used as an adjunct to overcome the potential drawbacks of 2D radiography in assessing the root canal anatomy. English CBCT, 2-Dimensional, 3-Dimensional, Diagnosis, Missed canal, Radiographyhttp://ijcrr.com/abstract.php?article_id=4491http://ijcrr.com/article_html.php?did=4491

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareThree-dimensional Localization of Impacted Maxillary Canine and Assessment of Adjacent Root Resorption Incidence using Cone-Beam Computed Tomography English5966Alkyssi Hana’a AEnglish Al-Mogahed Naela MEnglish Alnajjar Latifa AEnglish Alharazi Ghamdan AEnglish Aldhorae Khaled AEnglish Altawili Zainab MEnglish Dahan Faez NEnglishIntroduction: The most common complication related to canine impaction is root resorption. Aims: To investigate the relationship of selective linear measurements of maxillary impacted canine to the incidence of adjacent root resorption by using CBCT scan records. Methodology: The linear measurements selected were: impacted canine crown width, available space for canine eruption, distance from canine cusp tip to the midline and occlusal plane, and resorption grade. Mann Whitney U test was used to compare nonparametric variables, with a significance threshold set at 5%. The correlation coefficient at 95% CI was used to investigate the relationship between resorption and variables. Result: Our sample comprised of 100 subjects. Of them, (30%) were bilateral and (70%) were unilateral. Regarding impaction localization frequency, 87.6% palatally, 8.4% buccally than within arch (3.8%). The resorption was mostly located at the apical third of adjacent teeth. In term of resorption, 28.4% of subjects had single tooth resorbed, 56% had two teeth resorbed, and three teeth resorption in 12.6% of subjects. Resorption severity was higher frequent in grade I (31.5%). There was an association of resorption incidence to type of impaction = 0.173, p= 0.048, contact relationship = 0.995, p< 0.01, and location of contact = 0.613, p< 0.01. Conclusion: Correlation found between root resorption to contact relationship and location of contact. Resorption was mostly encountered with lateral incisors, and grade 2 was more frequently seen, with the common area being the apical third. EnglishCanine impaction, CBCT, Lateral incisor, Orthodontic, Premolar, Root resorptionhttp://ijcrr.com/abstract.php?article_id=4492http://ijcrr.com/article_html.php?did=4492

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareThe Incidence of Hip Fractures in the Study Population: A Retrospective Study English6770Muhammad Tahir LakhoEnglish Sajjad Ali BughioEnglish Abdul Rehman KhanEnglish Zahoor Illahi SoomroEnglish Asfandyar KhanEnglish Madan LalEnglish Niaz Hussain KeerioEnglishIntroduction: Hip fractures can occur when the femoral neck, the region between the larger and lesser trochanters, or the area below the lesser trochanter breaks. Intertrochanteric fractures are extracapsular fractures of the proximal femur that occur between the greater and lesser trochanters. A subtrochanteric hip fracture occurs when a break between the region 5 cm below the lesser trochanter. Aim: To determine the incidence of hip fractures in the study population Methodology: This study comprised a total of 670 patients. There were 315 (47%) males and 355 (53%) females. The Proforma was created to record demographic information, hip fracture complications and lab test results. Every patient who was a part of this study gave their written informed permission. Before collecting data and publishing it in a medical publication, an ethics committee’s consent was obtained. The participants were chosen using a non-probability sequential selection approach. Results: The present studies show that higher numbers of hip fractures were observed in older age (above 66 years), in which 69% of females and 57% were males. The major cause of hip fracture was fall and slippage that broke the hip bone, it was found more in females (81.6%) than males (39.7%). Complications were observed due to waiting for their operative procedures. The delay has led to pulmonary, cardiac problems, and bedsores. However, in 80% of cases, the union of hip fracture was observed. Conclusion: The present study concluded that the incidence rate of hip fracture increases with respect to age. In males, a major cause of hip fracture was accidents fractures are more prevalent in females, and fall and slippage are the major causes. EnglishHip fractures, Incidence, Hip Fractures, Subtrochanteric, Intertrochanteric, Operative procedureshttp://ijcrr.com/abstract.php?article_id=4535http://ijcrr.com/article_html.php?did=4535

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareA Cross-Sectional Study for the Analysis of Commonly Attained Fractures in Patients Admitted Followed by a Motorcycle Accident English7174Zulfiqar Ali ZaurEnglish Imtiaz Ahmed TagoEnglish Niaz Hussain KeerioEnglish MehtabullahEnglishGhiasuddin JanEnglish Sartaj LakhaniEnglish Syed Shahid NoorEnglishEnglishMotorbike accidents, Fractures, Femur, Tibia, Humerus, Radius and ulnahttp://ijcrr.com/abstract.php?article_id=4536http://ijcrr.com/article_html.php?did=4536

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareImpact of Glossopharyngeal Breathing on Expectoration, Airway Clearance and Vital Capacity in Pulmonary Tuberculosis Patients: A Cross-Sectional Study English7580Urooj BhattiEnglish Sikandar Ali SangrasiEnglish Sadia EffendiEnglish Feriha Fatima KhidriEnglish Waseem ShaikhEnglish Keenjher RaniEnglishIntroduction: Mycobacterium Tuberculosis is the main agent causing Pulmonary Tuberculosis spread by droplet nuclei that remain airborne for minutes to hours after expectoration via coughing, talking, sneezing or singing. TB is characterized by accumulated mucous in the airway creating a favorable environment for secondary host infections to grow, reduced vital capacity, weakness of respiratory musculature, atelectasis leading to respiratory failure. Aim: To assess the impact of glossopharyngeal breathing on expectoration, airway clearance and vital capacity in pulmonary tuberculosis patients. Methodology: Inpatient tuberculosis patients were selected via a simple random sampling technique with a sample size of 197 participants. The application of Glossopharyngeal Breathing (GBP), with the objective of facilitating cough by piston pumping maneuver for exculpating the mucus from lungs hence aims to increase the vital capacity and overall lung compliance. Before and after performing glossopharyngeal breathing, the vital capacity was measured with a spirometer for assessing the outcomes. Results: The increase in exculpating mucus rate with aid of a different breathing pattern, glossopharyngeal breathing was beneficial in increasing lung compliance and vital capacities (p-value of 0.0001) and also enhancing the strength of the respiratory muscle in patients who are suffering from decreased breathing rate due to accumulation of mucus in the airway. Conclusion: The experimental study has established data on the effects of GPB on expectoration, VC and chest tightness in pulmonary tuberculosis patients. According to the data collected, the average age affected was adults with weak immunity. Research shows that assistance for physiotherapists and other health care providers in hospitals as it is cost-effective, easy to perform and less time-consuming. EnglishPulmonary tuberculosis, Glossopharyngeal breathing, Adults, Expectoration, Lung compliance and vital capacities, Piston pumping maneuverhttp://ijcrr.com/abstract.php?article_id=4537http://ijcrr.com/article_html.php?did=4537

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareManagement of Complications of Septoplasty; a Cross-sectional Comparative Study between Silicon Nasal Splints, Plastic Splints and without Splints for the Correction of the Deviated Nasal Septum English8184Tahir Hussain KhanEnglish Mukhtar IbrahimEnglish Ashfaq Hussain RanaEnglish Muhammad AfzalEnglish Muhammad FarooqEnglish Muhammad Shahzad AnwarEnglishIntroduction: In otorhinolaryngology, practice deviated nasal septum is a very common issue. Multiple theories demonstrated that deviated nasal septum started from birth moulding to the trauma to the nose. Sometimes surgery is performed to the approach of paranasal sinuses but the most common indication for septoplasty is nasal obstruction. Aim/Objectives: To compare the management of complications after septoplasty in different groups by using nasal splints, plastic splints and without a splint. Methodology: One hundred and fifty patients were selected randomly having deviated nasal septum (DNS) for septoplasty. We divided all patients into three different groups i.e., Group I (without splints), Group II (silicon splints), and Group III (plastic splints). Fifty patients were enrolled on each group. We measured the severity of pain by using a visual analogue scale, post-operated bleeding, post-operated septal hematoma, post-operated nasal adhesion, saddle nose deformity, and septal perforations. Data was entered in SPSS software by using version 20. Results: Among 150 patients, ninety-five were male and 55 were female. Pain score (severe pain) in Group I was 0%, in Group II, it was 20% and in Group III, it was 30%, showing the severity of pain was less in Group I. Moderate pain was more (30%) in patients of Group III. Nasal bleeding was noted in 16% in Group I, 18% in Group II, and 80% in Group III. Nasal adhesions were more in Group I, i.e., 24 patients (48%), in Group II and in group III, it was 8%. The hematoma was more in Group III. Saddle nose deformity was seen in 2 patients in group III. Septal perforations were seen in 6 patients in Group I and 1 patient in group III. Conclusion: Silicon nasal splints are good and effective; patients were more comfortable and have fewer complications when compared to plastic splints and without splints. EnglishSeptoplasty, Silicone nasal splints, Septal perforation, Nasal adhesion, Saddle deformity of nose, Otorhinolaryngology practicehttp://ijcrr.com/abstract.php?article_id=4581http://ijcrr.com/article_html.php?did=45811. Hafeez M, Iqbal K. Septoplasty without nasal packing. Gomal Journal of Medical Sciences. 2010 Dec 31; 8(2) :141-142. 2. Naqi SA, Ahmad MU, Umar MA, Karmani J, Hussain T. Intranasal Adhesion Formation in Post-Septoplasty Patients. Journal of Rawalpindi Medical College: JRMC. 2018 Dec 3;22(4):331- 333 3. Varghese GM. Septoplasty without Packing, Splints or Clip-Our Experience. Int J Surg Surgical Tech. 2017; 1(2):000108. 4. Júnior RG, Brandão FH, de Sousa Carvalho MR, de Aquino JE, de Paula SH, Fabi RP, et al. Frequency of Nasal Synechia after Septoplasty with Turbinectomy with or without the Use of Nasal Splints. Surgery. 2008; 6:7. 5. Kaur J, Singh M, Kaur I, Singh A, Goyal S. A comparative study of gloved versus ungloved Merocel® as nasal pack after septoplasty. Nigerian journal of clinical practice. 2018; 21(11):1391- 5. 6. Law RH, Ko AB, Jones LR, Peterson EL, Craig JR, Deeb RH. Postoperative pain with or without nasal splints after septoplasty and inferior turbinate reduction. Am J Otolaryngol. 2020 Nov 1; 41(6):102667. 7. Lau J, Elhassan HA, Singh N. History of intranasal splints. J Laryngol Otol. 2018 Mar 1; 132(3):198-201 8. Mundinger GS, Shanavas Z, Kontis TC. Could your patient have swallowed their nasal splint after septoplasty? Seeing is believing. Aesthet Surg J. 2016 Feb 1; 36(2): NP68-70. 9. Al-Mazrou KA, Zakzouk SM. The impact of using intranasal splints on morbidity and prevalence of adhesions. Saudi Med J. 2001 Jul;22(7):616-8. PMID: 11479645. 10. Deniz M, Çiftçi Z, I??k A, Demirel OB, Gültekin E. The impact of different nasal packings on postoperative complications. Am Otolaryngol. 2014 Sep 1; 35(5):554-7. 11. Quinn JG, Bonaparte JP, Kilty SJ. Postoperative management in the prevention of complications after septoplasty: a systematic review. Laryngoscope. 2013 Jun; 123(6):1328-33. 12. Ardehali MM, Bastaninejad S. Use of nasal packs and intranasal septal splints following septoplasty. Int J Oral Maxillofac Surg. 2009 Oct 1; 38(10):1022-4. 13. Shah G. Comparison of Septoplasty with and without Nasal Packing: Its Association with Post-Operative Nasal Adhesion Formation. Journal of Islamabad Medical & Dental College (JIMDC). 2018 Nov 18; 7(3):169-73. 14. E?ki E, Y?lmaz ?. Pack free septoplasty: functional outcomes and complications. Kulak Burun Bogaz Ihtis Derg. 2015 Sep 1; 25(5):275-8. 15. Kuboki A, Kikuchi S, Asaka D, Onda N, Nakayama T, Kojima H, et al. Nasal silicone splints and quilting sutures using a septum stitch device following septoplasty: a prospective comparative study. European Arch of Otorhinolaryngol. 2018 Jul; 275(7):1803-9. 16. Amin AK, Hasan DA, Jaff AM. Trans-septal suture method versus intranasal silicone splint in septoplasty. Int J Tech Res Appl. 2015; 3(3):159-65. 17. Coelho RG, Brandao FH, de Sousa Carvalho MR, de Aquino JE, de Paula SI, Fabi RP. Frequency of nasal synechia after septoplasty with turbinectomy with or without the use of nasal splints. Inti Arch Otorhinolaryngol. 2008;12(1):24-27.

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareCorrelation of Acute Respiratory Tract Infection with the Vitamin D deficiency in Children: A Cross-Sectional Study English8587Faiqa HassanEnglish Naila BaiEnglish Oam ParkashEnglish Mahtab MemonEnglish Batool HassanEnglish Priya RaniEnglishIntroduction: On a global level, the prevalence of respiratory tract infections (RTIs) is more than any other type of infection in children. One of the possible causes of the development of these infections is the deficiency of Vitamin D. In the process of synthesis of peptide cathelicidin, a vital role is played by Vitamin D. Peptide cathelicidin eventually protects against the microbial activity of certain infectious bacteria and viruses. It also causes the prevention of replication of the influenza virus. Moreover, Vitamin D also increases the immunity of the body. The presence of a normal physiological level of Vitamin D in the body is highly advantageous in the protection of the body against RTIs. Aim/Objectives: To assess the correlation of Acute Respiratory Tract Infection with Vitamin D deficiency in children. Methodology: A total of 120 children were included in the study. The age range of the participants was from 1 months to 5 years. A questionnaire was prepared to record the medical histories of all the patients. For the identification of the level of Vitamin D, blood samples of all the participants were collected and sent to the laboratory of the hospital. According to the exclusion criteria, the participants having genetic diseases such as hypophosphatemic rickets, X-linked rickets and hereditary vitamin D-resistant rickets, were excluded from the study. Results: The average level of vitamin D in the participants with normal vitamin D was 15±9.5 ng/mL. Whereas, the average vitamin D level in participants having respiratory tract infection was 5±5.2 ng/mL/ which was much lower compared to the healthy individuals. The level of vitamin D had shown association with lower, upper and recurrent infections of the respiratory system (p English Respiratory tract infections, Vitamin D deficiency, Children, Infections, common cold, average vitamin D levelhttp://ijcrr.com/abstract.php?article_id=4582http://ijcrr.com/article_html.php?did=45821. Taylor S, Lopez P, Weckx L, Borja-TaboraC, Ulloa-Gutierrez R, Lazcano-Ponce E, et al. 2017. Respiratory viruses and influenza-like illness: epidemiology and outcomes in children aged 6 months to 10 years in a multi-country population sample. J Infect. 74(1), pp.29-41. 2. Barlow PG, Svoboda P, Mackellar A, Nash AA, York IA, Pohl J, et al. Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37. PloS one. 2011 Oct 21; 6(10): e25333. 3. Esposito S, Lelii M. Vitamin D and respiratory tract infections in childhood. BMC infect Dis. 2015; 15: 487. 4. Grant CC, Kaur S, Waymouth E, Mitchell EA, Scragg R, Ekeroma A, et al. Reduced primary care respiratory infection visits following pregnancy and infancy vitamin D supplementation: A randomized controlled trial. Acta paediatr. 2015 Apr; 104(4):396-404. 5. Xiao L, Xing C, Yang Z, Xu S, Wang M, Du H, et al. Vitamin D supplementation for the prevention of childhood acute respiratory infections: a systematic review of randomized controlled trials. Br J Nutrition. 2015 Oct; 114(7):1026-34. 6. Litonjua AA, Carey VJ, Laranjo N, HarshfieldBJ, McElrath TF, O’Connor GT, et al. 2016. Effect of prenatal supplementation with vitamin D on asthma or recurrent wheezing in offspring by age 3 years: the VDAART randomized clinical trial. Jama, 315(4), pp.362-370. 7. Kazi MY, Aamir K, Rana MN, Farooq MA. Frequency of vitamin D3 deficiency in children presenting with frequent sinopulmonary infections. Pakistan Pediatric Journal. 2013; 37(2):101- 5. 8. Haider N, Nagi AG, Khan KM. Frequency of nutritional rickets in children admitted with severe pneumonia. JPMA. The Journal of the Pakistan Medical Association. 2010 Sep 1; 60(9):729-32 9. Webb AR, Kazantzidis A, Kift RC, Farrar MD, Wilkinson J, Rhodes LE. Meeting vitamin D requirements in white Caucasians at UK latitudes: providing a choice. Nutrients. 2018 Apr 17; 10(4):497. 10. Holick MF. Biological effects of sunlight, ultraviolet radiation, visible light, infrared radiation and vitamin D for health. Anticancer Res. 2016 Mar 1; 36(3):1345-56. 11. Edis Z, Bloukh SH. Vitamin D Deficiency: Main Factors Affecting the Serum 25-Hydroxyvitamin D ([25 (Oh) D]) Status and Treatment Options. Oncology. 2016; 8:9. 12. Al-Daghri NM, Al-Attas OS, Yakout SM, Alnaami AM, Wani K, Alokail MS. The association of serum 25-OH vitamin D with asthma in Saudi adults. Medicine. 2018 Sep; 97(36).e12286. 13. Hayes A, Cashman KD. Food-based solutions for vitamin D deficiency: putting policy into practice and the key role for research. Proc Nutr Soc. 2017 Feb; 76(1):54-63. 14. Pham H, Waterhouse M, BaxterC, Romero BD, McLeod DS, Armstrong BK, et al. 2021. The effect of vitamin D supplementation on acute respiratory tract infection in older Australian adults: an analysis of data from the D-Health Trial. Lancet Diabetes Endocrinol, 9(2), pp.69-81

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022August20HealthcareColor Doppler and Transvaginal Sonography; Accuracy in the Diagnosis of Endometrial Pathologies in Women with Abnormal Uterine Bleeding: A Cross-sectional Study English8893Sabita DeviEnglish Paras MangiEnglish Pinkey KumariEnglish Shazia RamzanEnglish Erum IlyasEnglish Pari Gul BalochEnglishIntroduction: Abnormal uterine bleeding (AUB) can occur at any age in a woman’s life, and it is more prevalent in the pre-menopausal age group. Although anovulation is the most prevalent endometrial cause, other major reasons include endometrial hyperplasia, endometrial adenomatous polyps and cancer. For patients of all ages, it is one of the most prevalent presentations in Gynecology OPDs. AUB has a major impact on health-related quality of life, necessitating quick intervention. AUB treatment is difficult without a good diagnosis. As a result, pre-menopausal and post-menopausal women with AUB must have a thorough examination to rule out endometrial cancer. Aim: To assess the role of transvaginal ultrasound and color Doppler tomography (CDTU) in irregular uterine bleeding and correlate these findings with histological diagnosis. Methodology: The present study included 92 individuals with abnormal uterine bleeding (AUB), in those TVS, and Color Doppler was used to evaluate the endometrial pathologies. Endometrium, uterine size and any uterine or adnexal disease were evaluated during the TVS. Spiral arteries of the endometrium and uterine arteries were studied for their vascular patterns. The RI and PI of the uterine artery were determined. For PI, a cutoff of 1.83 was used, while for RI, a cutoff of 0.81 was used. The results were then compared to endometrial histology. Results: According to TVS, (see Table 1) the most common causes of AUB were leiomyoma (15.2%), polyp (12%), PCOS (9.8%), adenomyosis (5.43%)and endometrial development (3.3%). The uterine indicators of RI (0.81) and PI (1.83) of the uterine artery by CDTU revealed 11 patients with probable cancer. For AUB M, the TVS with CDTU specificity and sensitivity was 100 percent and 90.77 percent, respectively. The positive predictive value was 45%, whereas the negative predictive value was 100%. Conclusion: The use of vascular impedance and color Doppler of the uterine artery and endometrial spiral arteries improves the diagnostic accuracy of TVS for the prediction of endometrial diseases. It makes screening for malignant and premalignant lesions easier. EnglishAbnormal Uterine Bleeding, Endometrial Hyperplasia, Color Doppler, Transvaginal-sonography, Uterine artery indices, Carcinoma Endometrium.http://ijcrr.com/abstract.php?article_id=4583http://ijcrr.com/article_html.php?did=4583

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareFrequency of Various Complications in Teenage Pregnancy and Adult-Age Pregnancies: A Cross-Sectional Study English9497Humaira TahirEnglish Mubushra SaminaEnglish Farzana AzharEnglish Zakia BanoEnglish Sundas AhmadEnglish Saima KhanEnglishIntroduction: A major public health issue in the world is teenage pregnancy and its consequences. Sixteen million birth occurs in teenage pregnant women between 15-19 years of age in the world. Aim/Objectives: To find the frequencies of pre-eclampsia, postpartum hemorrhage, birth asphyxia, anemia and intrauterine death (IUD) in teenage pregnancy and adult-age pregnancy. Methodology: A total of two hundred patients were booked for ante-natal care and patients were divided into two different groups equally i.e., teenage pregnancy and adult-age pregnancy (TP Group and AP Group). Teenage pregnancy group ranged from 14 to 19 years, and AP Group ranged from 20-30 years. One hundred (100) pregnant ladies were registered for each group. Those pregnant women who had co-morbid were excluded from the study. Pregnant women were booked for ante-natal care from twenty-eight weeks of pregnancy to forty-one weeks of pregnancy for both groups. Result: The mean age of pregnant women was 16.25 ±4.90 years in the teenager pregnancy group (TP Group) and 26.00 ± 5.00 years in the adult-age pregnancy group (AP Group). The mean BMI of patients was 24.50 ± 0.75 kg/m2 in the TP Group while it was 26.25 ± 3.50 Kg/m2 in the AP Group. The concentration of mean hemoglobin was 9.25 ± 0.75 mg/dl in the teenager pregnancy group and it was 12.50 ± 0.50 mg/dl in the adult-age group (AP Group) and the p-value was 0.003 (significant). Mean systolic blood pressure was 130mm of Hg in the TP Group, and 120mm of Hg in the AP Group while mean diastolic blood pressure was 85mm of Hg in Teenage pregnancy and 75mm of Hg in Adult-age pregnancy. Anemia, pre-eclampsia, intrauterine death (IUD), postpartum hemorrhage (PPH) and birth asphyxia were more in the teenage pregnancy group as compared to the adult-age pregnancy group. The mean gestational age in teenage pregnancy was 30.75±1.25 weeks and it was 38.80 ± 0.70 week in the adult-age pregnancy group. Conclusion: The frequency of pre-eclampsia, postpartum hemorrhage, birth asphyxia, intrauterine death and anemia were more in teenage pregnancy (TP Group). EnglishPre-eclampsia, Teenagers, Adult age pregnancy, Birth asphyxia, Postpartum hemorrhage, Teenage pregnancy group (TP Group)http://ijcrr.com/abstract.php?article_id=4584http://ijcrr.com/article_html.php?did=4584

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20HealthcareMean Time to the First Request for Analgesia Post-Operatively between Pre-Emptive and Intra-Operative Paracetamol Groups in Cases of Septoplasty: A Comparative Prospective Study English98102Tahir Hussain KhanEnglish Ashfaq Hussain RanaEnglish Muhammad FarooqEnglish Muhammad AfzalEnglish Mukhtar IbrahimEnglish Rao Ammar NasirEnglishIntroduction: The difficulty of breathing due to nasal blockage is a common grievance in ENT-based practice. Nearly eighty percent of the people have some grade of deviated nasal septum (DNS). Septoplasty is the choice for the correction of DNS. Septal cartilage provides structural support to the dorsum of the nose; it may have also deviated during the birth of a baby. The acquired septal deviation may occur after trauma in childhood or adult life. Treatment of DNS is septoplasty and it is widely used. Aim/Objectives: To compare the mean time to the first request for analgesic demand postoperatively in cases of septoplasty by using intravenous paracetamol pre-emptive versus intraoperative. Methodology: A total of sixty-four patients were included in this study with both genders who had deflected nasal septum. Age ranges between 18 to 40 years. We divided the patients into two groups randomly. Groups A, and Group B i.e., pre-emptive and Intraoperative paracetamol groups. A total of thirty-two patients were in each group. All patients underwent septoplasty under general anesthesia. In group A, patients received paracetamol 1gm by intravenous route fifteen minutes before the induction of general anesthesia while in Group B, patients received 1gm I/V paracetamol 1gm. at the end of surgery before extubating the endotracheal tube. Postoperatively, patients were shifted to the post-anesthesia care unit (PACU) for standard monitoring and observation. Time for the first analgesic demand in minutes was noted by the on-duty resident doctor. Results: The mean age of patients in the pre-emptive paracetamol group was 29.50 ± 9.50 years and the mean age of the patients in the intraoperative paracetamol group was 30.50 ± 9.50 years and the p-value was 0.819. The mean time for the first analgesic demand in the pre-emptive paracetamol group was 180.97 ± 14.25 minutes and the meantime for the first analgesic demand in the intraoperative paracetamol group was 170.89 ± 14.04 minutes (p-value 0.001). Conclusion: Substantial difference was noted in the meantime to the request for the first analgesic demand postoperatively in the septoplasty cases between pre-emptive paracetamol versus intraoperative paracetamol. The mean time consumed for the first analgesia is lengthy while using pre-emptive intravenous paracetamol as compared to intraoperative paracetamol. English Intraoperative, Postoperative, Pre-emptive, Septoplasty, Time to the first request, Intraoperative paracetamolhttp://ijcrr.com/abstract.php?article_id=4585http://ijcrr.com/article_html.php?did=4585

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52411410EnglishN2022May20Healthcare Fetomaternal Outcome in Antepartum Hemorrhage; A Cross-Sectional Study at Feto-Tertiary Care Hospital of Sindh, Pakistan English103107Noureen AbbasiEnglish Quratulain QureshiEnglish Urooj AbbasiEnglish Noor ul ain AzizEnglish Feriha Fatima KhidriEnglish Sehrish RasoolEnglish Introduction: Antepartum hemorrhage is the bleeding from the genital tract following the completion of 28 weeks of pregnancy till full term. It is an obstetrical emergency and a leading cause of maternal and perinatal death and morbidity. Objectives: This study was conducted to determine the frequency of maternal and fetal complications in women with antepartum hemorrhage. Methods: It was a cross-sectional study held at the Department of Gynecology and Obstetrics unit IV, Liaquat University of Medical and Health Sciences, Jamshoro between 2017 and 2019. This study enrolled 158 women with a history of antepartum hemorrhage using non-probability consecutive sampling. The fetal and maternal outcomes of the patients were recorded. Maternal outcomes were assessed according to age, gravidity and gestational week. Data was analyzed in SPSS 20. Results: The average age of the women was 25.77±4.15 years. Anemia was the most common maternal outcome 102(64.6%) followed by disseminated intravascular coagulation (DIC) 24(15.2%), shock 12(7.6%), postpartum hemorrhage (PPH) 11(7%) and maternal mortality 5 (3.1%). Preterm birth and low APGAR score were the most frequently fetal outcomes that were observed in 69 (43.7%) and 50 (31.6%) cases, respectively. There was a significant association of DIC with gravidity and gestational age. Anemia was significantly associated with gestational age more frequently among mothers with EnglishAntepartum hemorrhage, Fetal outcome, Frequency, Gestational age, Gravidity, Maternal outcomehttp://ijcrr.com/abstract.php?article_id=4600http://ijcrr.com/article_html.php?did=4600