Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareThe Impact of CA9 Gene Polymorphism (RS2071676) on Oral Cancer Susceptibility - An In-Silico Study English0208Suvarna KEnglish Vijayashree Priyadharsini JEnglish Gheena SEnglish Pratibha RamaniEnglish Abilasha REnglish Hannah REnglishBackground: Oral cancer accounts for 2 to 4% of all cancer and 90% of oral cancer cases are squamous cell carcinoma. Apart from etiological factors genetic factors also play an important role in oncogenesis. The common type of sequence variations is single nucleotide polymorphisms (SNPs), described as a change in the coding and amino acids sequence in the related proteins which could confer protective or lethal effects on the organism. Objective: To analyze the genetic variation in the CA9 gene (rs2071676) and to compare allele frequencies in different populations worldwide. The rs2071676 variant of the CA9 gene is a missense variant that results in the substitution of the amino acid methionine in place of valine. Methods: Genotype frequencies of the SNP rs2071676 were collected from the Ensembl database for different populations and the deviations were analyzed. Furthermore, the expression profile of the CA9 gene in HNSCC was assessed using in-silico tools. The survival of patients based on the expression of the CA9 gene was also assessed. Results: The present study identified deviations in allele frequencies for rs2071676 polymorphism between different populations. The minor allele frequency in the ancestral population or the African population was found to be much lower than the other populations such as American, East Asian, and South Asian, where both the alleles showed similar frequencies. Conclusion: The significant deviation between allele frequencies in different groups provides clues about the positive selection of these alleles in certain populations. This led us to further investigate the plausibility of association of the CA9 gene with HNSCC. The intriguing facts observed from the study could aid in revealing the association between the CA9 gene and the progression of oral cancer. EnglishCA9 gene, Polymorphism, SNP, Oral cancer, Genetic variation, In silico studyhttp://ijcrr.com/abstract.php?article_id=3233http://ijcrr.com/article_html.php?did=3233

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcarePrevalence of Oral Cancer in Patients Reporting to Private Dental Hospital English0914Neha Sharma MEnglish Senthil Murugan PEnglish L LeelavathiEnglishBackground: Oral cancer is one of the 10 most common cancers in the world, with delayed clinical detection, poor prognosis, for the disease, and expensive therapeutic alternatives. Oral cancer is a preventable disease, risk factors and natural history is already being known, where biomedical sciences and dentistry, in particular, are likely to improve their poor clinical indicators. Objevtive: The aim of this study is to assess the prevalence of oral cancer among patients visiting Saveetha Dental College. Methods: A retrospective study was carried out and the case records of patients having oral cancer were collected by reviewing patient records and analyzing the data of 86000 patients from June 2019 to April 2020. Patients diagnosed with oral cancer were selected. The data were collected and subjected to statistical analysis and correlation using SPSS software. Results: In this study, it was found that 82% of the total patients diagnosed with oral cancer were males and 18% of them were females. It was also found that the commonest site involved was the buccal mucosa (31%). The findings of this study revealed that oral cancer is more prevalent among males and that the commonest site involved is the buccal mucosa. Conclusion: From this study it is concluded that the prevalence of oral cancer is more among males and according to the site involved, it’s more commonly involved in buccal mucosa when compared to other sites. English Buccal mucosa, Correlation, Diagnosis, Gender, Oral cancer, Subsitehttp://ijcrr.com/abstract.php?article_id=3234http://ijcrr.com/article_html.php?did=3234

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareAssociation of Aurka Gene Polymorphism (RS2064863) with Oral Squamous Cell Carcinoma Development - An In Silico Study English1924Casilda Sushanthi LEnglish Vijayshree Priyadharsini JEnglish Hannah REnglishBackground: Oral carcinoma is the most common and sixth cause of death worldwide. AURKA gene encodes Aurora kinase-A, cell-cycle regulated protein which is involved in microtubule formations and stabilization of spindle poles during chromosome segregation. Overexpression of the gene is often associated with chromosome instability. Objective: The study investigates the association of AURKA gene polymorphism in oral squamous cell carcinoma (OSCC) progression. Methods: The present study follows an observational study design which employs in-silico tools to assess the frequency of the alleles related to the polymorphism (rs2064863) in different populations and its possible consequences. Results: The polymorphism (rs2064863) of AUKRA gene selected was an intron variant with the minor allele frequency of 0.37 for the G allele. Interestingly, the ancestral population or the African population demonstrated a frequency of 83% for the T allele and 16% for the G allele, where other populations such as American, European and South Asian populations presented with different allele frequencies in which both the alleles occur with similar frequencies in the population. Conclusion: The present study revealed the possible reasons for the positive selection of the minor allele in these populations, which could provide clues on the possible association of this variant with OSCC in the south Asian population. EnglishAURKA, Oral Squamous Cell Carcinoma, Polymorphism, Aneuploidy, Positive selection, Allele frequencieshttp://ijcrr.com/abstract.php?article_id=3236http://ijcrr.com/article_html.php?did=3236

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareFactors Influencing Onset of Habit and Non-Habit Related Oral Squamous Cell Carcinoma English2529Chithralekha BEnglish Gheena SEnglish Madhulaxmi MarimuthuEnglishIntroduction: Oral cancer results due to the persistence of potentially malignant disorders (PMD) over a chronic duration. It is the sixth most common cancer prevailing all over the world. The incidence of oral cancer in Asians has been reported to be very high due to various personal habits and poor knowledge about the occurrence and consequences if diagnosed with a deadly disease such as oral cancer. In the study, all the possible causes for occurrences of oral cancer have been extensively discussed and the study has also tried to investigate the possible underlying reasons behind the occurrence of the disease in a select population namely non-habit-related Oral Squamous Cell Carcinoma (OSCC). Aim: The aim of the study was to evaluate the diet and other habits affecting non-habit oral cancer patients. Materials and Methods: The study was performed in a university setting. The study reviewed patient records and analyzed the data of 86000 patients between June 2019 and March 2020. The collected data were compiled and tabulated using Microsoft Excel. The tabulated data were then reviewed and then exported to the SPSS platform for performing statistical analysis. Results and Discussion: The study has taken a total of six parameters. Of them, only one parameter showed statistical significance and the p-value was found to be 0.0001 (pEnglishOral cancer, Diet, Other habits, Personal habits, Pan chewing, Smokinghttp://ijcrr.com/abstract.php?article_id=3237http://ijcrr.com/article_html.php?did=3237

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareEvaluation of Accuracy between Habit History and Incidence of Oral Squamous Cell Carcinoma English3035Snega ThamilselvanEnglish Abilasha REnglish Pratibha RamaniEnglish Gheena SEnglish Hannah REnglishIntroduction: Oral squamous cell carcinoma (OSCC) is one of the most common cancers that affect the human population worldwide. The global incidence rate of OSCC is 47% which shows a recurrence of 30%. Objective: The aim of this study is to analyze the accuracy between risk factors and the incidence of OSCC. Methods: This retrospective study includes the subjects reported to the Department of Oral Pathology and Microbiology in Saveetha Dental College between 2019- 2020. Data on age, gender, lesion site, habit profile, diagnosis, and treatment were recorded and subjected to Pearson’s Chi-square analysis for correlation between habits and other variables. Results: A total of n=77 cases were included. Male: Female ratio is 3.5:1 with maximum cases in the 5th and 6th decades of life. Totally 63.3% reported OSCC without habits and 36.7% reported OSCC with habits pan/betel quid chewing was the most frequently reported habit and buccal mucosa was the common site. Conclusion: Our study showed that the incidence of OSCC is more among the male population in the 4th - 6th decade with at least one predisposing oral habit and identified buccal mucosa to be the most commonly involved site. This study reflects the association of oral habits with the incidence and severity of the disease which quantifies the need for awareness for habit cessation among the public. EnglishAccuracy, Habits, Risk factor, Incidence, OSCC, Institutional level, Smoking, Tobaccohttp://ijcrr.com/abstract.php?article_id=3238http://ijcrr.com/article_html.php?did=3238

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcarePrevalence of Non-Habit-Associated Oral Squamous Cell Carcinoma and its Site Predilection - A Retrospective Institution Based Study English3641Krishnapriya UmashankarEnglish Gheena SEnglish Hannah REnglish Pratibha RamaniEnglish Abhilasha REnglishBackground: Worldwide Oral Squamous Cell Carcinoma (OSCC) is one of the most frequent malignancies, and it carries a bad prognosis with a global mortality rate of 1.9 deaths per 100,000 per year. Most cases of OSCC are preceded by asymptomatic clinical lesions collectively referred to as Oral Potentially Malignant Disorders (OPMDs). Objectives: The objective of the study was to describe the prevalence of Non-habit-associated OSCC and site predilection among patients visiting our institution. Methods: Of 50 oral squamous cell carcinoma, 15 cases were treated between July 2019 to February 2020 in our institution were identified as not having the habit of tobacco use during their lifetime. These cases were reviewed to gather data on multiple clinical-pathological variables. Results: The mean age of non-habit associated OSCC of the oral cavity was 59.9 years and 60% were males. The tumour was more commonly seen on the tongue followed by buccal mucosa. Conclusion: The Non-habit-associated OSCC is seen more commonly in the elderly with a male predilection. English Oral Squamous Cell Carcinoma, Non-smoker, Non-habit, Oral Cancer, Human papilloma virus, Carcinomahttp://ijcrr.com/abstract.php?article_id=3239http://ijcrr.com/article_html.php?did=3239

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareCorrelation of Site of Occurrence of Oral Squamous Cell Carcinoma and Level of Lymph Node Metastasis English4246Monica KEnglish Hannah REnglish Gheena SEnglish Pratibha RamaniEnglish Abhilasha REnglishIntroduction: Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral cavity, associated with poor prognosis. Risk factors associated are tobacco, alcohol, pan chewing, nutritional deficiency, etc. Metastasis is more commonly to cervical lymph nodes various studies have been done to study the pattern of metastasis, which helps surgeons predict the pattern and treatment planning. Objective: To evaluate the correlation between the site of occurrence of lesion and Levels of lymph node involvement in (OSCC) patients. Methods: This is a retrospective study conducted in an institution, a totally of 34 patients who were diagnosed with oral squamous cell carcinoma were included. Demographic data was collected from the management software and tabulated in a Microsoft Excel sheet and used for statistical analysis. Association between the site of lesion and Level of lymph node involvement is studied using the Chi-square test. Results: Well-differentiated squamous cell carcinoma (WDSCC) was more common than moderately differentiated squamous cell carcinoma (MDSCC). The more common site of lesion with lymph node involvement is tongue and buccal mucosa than the retromolar region and gingivobuccal sulcus, 60% of lesions in buccal mucosa show involvement in Level-1B and 2 followed by the tongue (45.5%) more in Level-5. The correlation between the site of lesion and Level of nodal involvement did not show statistical significance. Conclusion: This study provides a predictive model that appears to be reliable, simple, and may help as a guide for surgeons in planning neck dissections before surgery. English Oral squamous cell carcinoma, OSCC, Cancerization, Lymph node, Predictive model, Metastasishttp://ijcrr.com/abstract.php?article_id=3240http://ijcrr.com/article_html.php?did=3240

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcarePrevalence of Oral Carcinoma According to Age - A Hospital Based Study English4751Hemashee JEnglish Kathiravan SelvarasuEnglish Manjari ChaudharyEnglishIntroduction: Carcinoma has a major impact on society across the world and it is majorly a negative impact on life. Carcinoma appears in diverse morphological and histological patterns making it important to know the characteristics of the disease like demographic data which includes gender and age group affected, geographical presence, commonly affected sites of the oral cavity, treatment planning and its efficacy, and other factors to provide comprehensive treatment to the patients. Objective: The aim of this study was to find the prevalence of carcinoma according to age in patients. Methods: Retrospective study. Data were collected by reviewing case records of 86,000 patients among which 59 subjects who satisfied the inclusion criteria such as age, gender, site of carcinoma were included in the study. Data were tabulated and statistically analyzed using SPSS Software. Both descriptive and inferential statistics were employed. Results: Retrospective analysis showed that the prevalence of carcinoma was the highest (35.6%) among the subjects belonging to the age group of 41-50 years of age. Males (76.3%) had a higher prevalence. Conclusion: Prevalence of carcinoma in this was noted in the mid-age group and males are most commonly affected. Proper intervention at the early stage can prevent the deterioration of one’s life. EnglishAge, Carcinoma, Gender, Metastasis, Prevalence, Sitehttp://ijcrr.com/abstract.php?article_id=3241http://ijcrr.com/article_html.php?did=3241

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcarePrevalence and Age Distribution of Oral Squamous Cell Carcinoma - A Retrospective Study English5256Kadambari SriramEnglish Manjari ChaudharyEnglish Santhosh Kumar M PEnglishBackground: Cancers of all regions of the oral cavity, taking into account worldwide reports is considered to be represented as the sixth most common cancer in the world. Oral cancers are believed to result due to the accumulation of genetic and epigenetic alterations. Over the past few years, there has been an increasing trend in prevalence among younger persons. This makes Oral cancer a highly relevant issue of global public health. Objective: The aim of the present study is to evaluate the prevalence and age distribution of Oral Squamous cell carcinoma (OSCC) in patients of an institution. Methods: The study is a hospital-based retrospective study, and included patients visiting a Dental hospital. A total of 45 patients diagnosed with OSCC were included in the study. The age, gender, anatomic site, and history of habit were evaluated and tabulated in MS Excel. The data collected was imported to IBM SPSS Version 20.0 for Chi-Square analysis and results were obtained. Results: It was observed that OSCC was most prevalent in patients around 56 years of age. The lower arch was found to be the most frequent site of presentation (47%). The association between gender and the occurrence of OSCC was not statistically significant (p>0.05). Conclusion: Within the limits of this study OSCC was found to be most prevalent in the 5th-6th decade of life in the lower arch English Epidemiology, Human diseases, Oral cancer, Prevalence, Risk factors, Agehttp://ijcrr.com/abstract.php?article_id=3242http://ijcrr.com/article_html.php?did=3242

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareTypes of Antibiotics Administered in Patients Having Head and Neck Carcinoma Treated in Private Dental Hospital - A Retrospective Study English5762Amanthi GanapathiEnglish Jagadish VijayakumarEnglish JeevithaEnglishBackground: Patients undergoing head and neck oncological surgery are at great risk of developing complications especially postoperativeworld infection. Objective: The purpose of the study was to analyze the type of prophylactic administration of antibiotics. Methods: All the surgical and medical records of the patient from June 2019 to March 2020 was collected. Some patients had bacteriology data from wound swabs of patients were collected from the department of oncology and department oral and maxillofacial surgery. Results: Total of 39 patients out of which 11 patients had single antibiotics and 28 patients had a combination of antibiotics given. It was found in our study that most of the patients were administered with cefixime and metronidazole. Patients undergoing head and neck oncology surgery are at great risk of developing complications especially post-operative wound infection. Antibiotherapy seems to have efficacy when administered prophylactic in head and neck surgical procedure. Conclusion: To conclude our study, although we have other antibiotics used in head and neck cancer operated patients but Cefixime and Metronidazole, Ciproflaxicin were relatively more and commonly administered to patients affected with head and neck carcinoma. English Head and neck surgery, Antibiotic prophylaxis, Surgical site, Infection control, Bacterial contamination, Immunocompromisedhttp://ijcrr.com/abstract.php?article_id=3243http://ijcrr.com/article_html.php?did=3243

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareAssociation of Deleterious Habits with the Occurrence of Oral Malignant Lesions English6368Shivangi GaurEnglish Madhulaxmi MEnglish Hemavathy O REnglishBackground: Differences in incidence and pattern of oral cancer can be due to the overall effects of the prevalence of specific risk factors in a sample population. The low-income groups are at a wide exposure to risk factors such as tobacco chewing, gutka consumption, smoking, etc. Objective: The aim of this epidemiological study is to determine the association of deleterious habits already deemed as risk factors in patients with oral cancer at our centre. Methods: A retrospective analysis of patients undergoing treatment for oral cancer in our institution was done to identify patients with a positive association to habits - pan chewing, smoking, and gutka consumption. Statistical analysis was performed using the Chi-square test after data collection using SPSS software version 20. Results: Out of 48, 40 patients were included for the study based on the inclusion criteria. Females had no habits (20%), while males reported an incidence of pan chewing habit (15%), and gutka consumption (10%). Overall patients undergoing treatment for oral cancer with exposure to risk factors were 35% while 65% of patients had no association with deleterious habits and risk factors associated with oral cancer. A significant association was found between the prevalence of no habits and middle age group individuals. Conclusion: The study observed a trend towards a higher incidence of oral cancer in patients without exposure to deleterious habits. This strengthens the association of incidence of oral cancer with the genetic constitution of the individual and / or other risk factors not studied here. Many cancer registries should be scanned for confirmation of this trend shift elsewhere in the nation. Clinical Significance: Genetic and molecular analysis of specimens can help shed light on the etiological factors responsible for oral cancer in patients. English Oral cancer, Habits, Smoking, Pan chewing, Gutka, Tobaccohttp://ijcrr.com/abstract.php?article_id=3244http://ijcrr.com/article_html.php?did=3244

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareAwareness Among Dental Students on Reconstructive Surgery Following Resection During Oral Cancer Surgeries - A Questionnaire Survey English7781T. SanthoshEnglish Dinesh PrabuEnglish Sankari MalaiappanEnglishIntroduction: Oral cancer represents some 2% of all new cases worldwide that may arise in a human body and it is considered a serious public health problem. The resection of malignant tumors can result in anatomical defects. Post-resection management of such defects can bring back the physical and anatomical form of the facial structure lost to a certain extent. Objective: Aim of this study is to evaluate the awareness among dental students about reconstructive surgery. Methods: In this study, we evaluate the awareness of reconstructive surgeries and the flaps available for those surgeries among a group of dental students. In this study, we found students about (65%) were aware of the term obturator and its use. Results: In this study that the student understands reconstructive surgery is performed to restore the form and function of lost structures during cancer resection, students also responded yes (95) to the question about the term anastomosis. In overall association, we found there is less awareness about reconstructive surgery among undergraduate dental students. Conclusion: This study concluded that only postgraduates show adequate knowledge about reconstructive surgery which implicates the need for including research and studies about oral cancer and its reconstruction to undergraduates which can change their view about oral cancer management. English Flaps, Oral cancer, Pedicle flap, Reconstructive surgery, Resective surgeryhttp://ijcrr.com/abstract.php?article_id=3247http://ijcrr.com/article_html.php?did=3247

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareSaliva Based Oral Cancer Diagnosis - A Review English8286Sarojini KEnglish Brundha MPEnglish Smiline Girija ASEnglishOral cancer refers to any malignancy that develops around any part of the mouth like lips, pharynx. Oral squamous cell carcinoma is reported as the top three common malignancies in India. Despite the recent advances, oral cancer has been reported with higher mortality rates all over the world. Saliva has been identified to be an efficient tool in the early detection of oral malignancy and reduces the higher rate of mortality due to late diagnosis. The goal of this saliva-based diagnosis method is to detect malignancy at an early phase and which is a hallmark of salivaomics. The current review focuses on saliva-based oral cancer diagnosis. A review of the literature of research papers on saliva-based oral cancer diagnosis was done from articles duration between 2000 to 2020. Data collection was done through search engines and databases. Articles that met the inclusion criteria have been included. Saliva is a complex fluid containing several hormones, proteins, enzymes, cytokines, antibodies, salts, antimicrobial constituents, and is associated with a variety of systemic diseases. Saliva based diagnosis has been used in the diagnosis of systemic diseases and drug monitoring. Salivary biomarkers have been identified over the years specifically for early cancer detection which has attracted much research interest, especially for oral cancers. Extensive clinical applications of fluids in the human body have been found to diagnose and monitor human health. Detection of molecular markers like DNA, RNA, protein markers in saliva can be accurate and reliable methods for the diagnosis of oral cancer. English Biomarkers, Diagnostic tool, Oral cancer, Saliva, Salivary proteins, Salivaomicshttp://ijcrr.com/abstract.php?article_id=3248http://ijcrr.com/article_html.php?did=3248

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareAwareness on Risk Factors Associated with Oral Cancer Among School Students in Chennai English8794Sushma BEnglish Vishnu Priya VEnglish Karthik Ganesh MohanrajEnglish Gayathri REnglishIntroduction: Oral cancer is also known as mouth cancer that is the cancer of the lining of the lips, mouth, or upper throat. In the mouth, it commonly starts as a painless white patch and develops into red patches. It commonly looks like a persistent ulcer that does not heal and slowly grows. Symptoms may include difficult or painful swallowing, new lumps in the neck, swelling in the mouth, feeling of numbness in the mouth, or lips and risk factors include tobacco and alcohol use. Objective: To create awareness of risk factors of oral cancer among school students. Methods: The study setting was done using a prospective observational study in Saveetha Dental College (SDC). Approval is received from the scientific review board, (SDC). The sampling method is random sampling including the sample size of 100 participants. A self-structured questionnaire was prepared including 15 questions. Results: The results were collected and analyzed using statistical analysis using online SPSS software. According to the results, 65% of school students are aware of oral cancer. Almost 70% of school students believe that oral cancer leads to death. Students also know that smoking causes oral cancer. Conclusion: The survey demonstrated that school students are aware of risk factors associated with oral cancer but there is a lack of knowledge about it. So, creating awareness on knowledge of risk factors of oral cancer will be helpful for future generations. EnglishAwareness, Oral cancer, Oral hygiene, Risk factors, Smoking, Tobacco, Online surveyhttp://ijcrr.com/abstract.php?article_id=3249http://ijcrr.com/article_html.php?did=3249

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareEvaluation of Osseous Changes in Oral Carcinoma - 2D Vs 3D Imaging English95100Abhinaya LMEnglish Muthukrishnan ArvindEnglish Deepika RajendranEnglishIntroduction: Oral cancer is the eighth most common cancer and accounts for 2% of cancer death worldwide. In India, Oral cancer accounts for 30-50% of all cancers; with squamous cell carcinoma the most common. Radiologic assessment of bone invasion plays a major role to evaluate the extent of surgical bone resection. Objective: This study compares osseous changes in OSCC using Orthopantomogram (OPG) and Cone Beam Computed Tomography (CBCT). Methods: A retrospective analysis of patients who visited the Department of Radiology from June 2019 to March 2020 was included in the study. After reviewing 67 case records, 12 patients who were clinically and histopathologically proven as OSCC patients, and had undergone imaging, both OPG and CBCT for assessment were selected. Results: The study subjects included 4 female (33.3%) patients and 8 male (66.6%) patients. The predominant age group in the study was 40-50 years (41.7%). OSCC frequently involved mandible (75%); the posterior region (91.7%) and the commonly reported TNM staging were stage IV-A (66.6%) followed by stage-III (33.3%). Comparison of the OSCC and internal structure appearance in OPG there was a positive correlation seen and in comparison, to CBCT it was not statistically significant. On comparison for the involvement of adjacent structures and OSCC in OPG and CBCT, there was no significant difference noticed. Conclusion: CBCT can be recommended for imaging oral carcinoma of the maxillofacial region replacing 2D and high exposure medical CT imaging. EnglishCancer, CBCT, Imaging, OSCC, OPG, Squamous cell carcinomahttp://ijcrr.com/abstract.php?article_id=3250http://ijcrr.com/article_html.php?did=3250

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareA Retrospective Analysis on Types of Flap Design Used in Maxillary Carcinoma English105109Harini GEnglish Kathiravan SelvarasuEnglish Bala Krishna R NEnglishIntroduction: The removal of various maxillary tumors and further reconstruction is considered as a difficult phase. Objective: The aim of the study is to investigate the flap design used in maxillary carcinoma at Saveetha Dental College. Methods: This study was conducted for the patients who visited the Department of oncology between 1st June 2019-1st April 2020. Data was extracted by reviewing the information of the patient. Results: Out of 57 patients 17 patients (30%) were diagnosed with maxillary carcinoma. There was male predilection in this sample with 58.82% males and 41.18% females. Weber-Fergusson approach along with the modifications was used in 76.47%, midfacial degloving in 17.65% and palatal swing approach in 5.68% of the patients with maxillary carcinoma. Conclusion: We conclude that maxillary carcinoma resection was done predominantly among males and the most common age group which underwent surgical treatment for the same were in the age group of 41 to 50 years. Among various flaps used to resect the tumor, Weber-Fergusson (76.47%) was used in the majority of cases. Association between gender and age and type of flap used of maxillary carcinoma resection was tested using Chi-square analysis and it was found to be not significant. English Maxillary, Carcinoma, Incision, Flap, Weber Fergussonhttp://ijcrr.com/abstract.php?article_id=3252http://ijcrr.com/article_html.php?did=3252

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcareA Retrospective Study on Incidence of Maxillary Carcinoma in A University Setting English110114Nivetha GEnglish Kathiravan SEnglish Arvind SEnglishIntroduction: Oral cancer is considered as one of the major life threatening public health issues on a global scale. Oral cancer is ranked as the sixth most common cancer. Chewing tobacco/pan masala is considered to be the most potent risk factor for oral precancerous lesions and oral cancer. Objective: The aim of this study is to find out the incidence of maxillary carcinoma among oral cancer patients visiting Saveetha dental college. Methods: The study was carried out in Saveetha Institute of Oral Oncology at Saveetha Dental College and Hospitals. The data were collected from case records of patients who visited the unit, between July 2019 - March 2020 and entered in Excel sheets. The entered data were subjected to statistical analysis using SPSS software version 26. Results: Among 30 carcinoma patients, 8 patients had maxillary carcinoma which accounted for an incidence rate of 26.67%. Males and females were equally affected. Maxillary carcinoma was most noted in the age group 41-50 [50.00%] followed by 51- 60 age group [25.00%]. Statistically significant association was found between gender and maxillary carcinoma (p-value=0.037) whereas it was not statistically significant between age and maxillary carcinoma (p-value=0.766). Conclusion: Incidence of maxillary carcinoma reported was 26.7%, with equal gender predilection and most common in the 4th decade of life. English Age, Gender, Incidence, Maxillary carcinomahttp://ijcrr.com/abstract.php?article_id=3253http://ijcrr.com/article_html.php?did=3253

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Impact, Awareness, Prevalence, Association, Detection, and Recent Demographic Surveys of Various Oral Cancer FormsEnglishN2020December26HealthcarePrevalence of Cancer Among Different Subsites in the Oral Cavity English115118Vivek D. MenonEnglish M R MuthusekharEnglish Dinesh PrabuEnglishAim: To assess the prevalence of different sites of oral cancer. Materials and Methods: A retrospective study was done in an institutional setting. The data for the study was retrieved from the college’s patient records. All the patients who underwent management of oral cancer at a given time frame from June 2019 - March 2020 were taken into consideration. The patient’s name, age, gender, and site of lesion were retrieved and tabulated. The data was analyzed using software (SPSS). Results: A total 41 patients were included in this study, 33 being males and 8 female patients. The common site of occurrence of cancer was found to be most in buccal vestibule (39%), tongue (26.8%), buccal mucosa (12.2%), retromolar area (12.2%), alveolar mucosa (2.4%), lip (2.4%), neck (2.4%), and chest (2.4%). The majority of the patients who participated in this study were between 41-50 years of age. A cross analysis between age and site of cancer and gender and site of cancer was done. The most common age was found to be 41-50 years and more cases were seen in male patients. Conclusion: The most common site of cancer was found to be in buccal vestibule. More number of cases was seen in male patients and the age group in which most cases were seen was 41-50 years. English Oncology, Occurrence, Site, Head and neck, Carcinomahttp://ijcrr.com/abstract.php?article_id=3254http://ijcrr.com/article_html.php?did=3254