Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareFamily Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India English0207Amruta Choudhary (Ladke)English Mrunal NakadeEnglish Deepti ShrivastavaEnglishIntroduction: National Family Planning Programme was launched in 1952, and India was the first country to adopt such programme. Reduction of birth rate and population stabilization was the main aim of this programme, but with the current status, this aim seems to be a complete failure. This study will help to evaluate the knowledge, attitude, and practice of women of rural area of central India, towards family planning. Materials and Methods: This was a cross-sectional observational study. All participants were interviewed with the help of a predesigned questionnaire. Results: Total 400 cases were interviewed. Contraceptive users were more in 30-40 years range (64.61%) and least in group < 20 years (41.17%). Illiterate females (18.75%) had the least contraceptive usage and graduated (69.76%) had maximum. 97.5% females were aware about contraceptive measures and media (43.07%) was major source. Only 56.25% participants showed a positive attitude towards family planning methods. 53.25% were contraceptive users. 41.31% opted tubal ligation, 21.59% oral contraceptive methods, and 14.08% male condoms. 46.75% were non-users of contraceptive methods. Reasons were eager to conceive (39.03%), husband’s denial (18.71%). Among contraceptive users, 51.17% have no side effects whereas 45.07% had backache or generalised weakness, 36.61% had a vaginal infection, 28.64% had menstrual problems. Conclusion: The present study, clearly showed that having knowledge about family planning methods and practicing them in their routine life are two different things because practise is influenced by various socio-demographic factors. There is a need for a different approach toward the family planning programme.. EnglishWHO, Family planning, Husband’s denial, Contraceptivehttp://ijcrr.com/abstract.php?article_id=2735http://ijcrr.com/article_html.php?did=2735

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareCo-Relation of Left Ventricular Diastolic Dysfunction with Apache II Score in Sepsis Patients English0813Anjalee ChiwhaneEnglish Yogesh KhithaniEnglish Anuj VarmaEnglish Saurabh HadkeEnglishBackground: Sepsis is a leading cause of mortality and is a major cause of morbidity by causing end-organ damage as well as cognitive and physical disability in survivors. Sepsis can be defined as the presence (probable or documented) of infection together with systemic manifestation of infection. Patients with sepsis generally have multiple predisposing factors and sources of infection. Cardiac dysfunction adds up in increasing the mortality rate in patients with sepsis. Diastolic dysfunction can predict long term mortality and morbidity in sepsis and is recognized to be a major cause of heart failure with normal ejection fraction (LVEF>55%). Material and Methods: The study was done on subjects admitted in ICU under the department of Medicine. All patients above 18 years, those who gave their consent for the study or their relatives, also fulfilled the criteria for sepsis as mentioned in guidelines for sepsis. Though the calculated sample size with 50% proportion of sepsis in two years was 127, this study included 140 patients. Worst APACHE II scores were calculated during the period of admission within the first 24 hours. All the pathological and biochemical parameters were measured by standard laboratory techniques. Blood pressure was measured using a mercury sphygmomanometer, using a Riva-Roci cuff in the right hand in the supine position. Worst APACHE II score was calculated in the first 24 hours for the sepsis patients admitted in the Medicine intensive care unit and was interpreted. Results: In the present study on 140 patients, the mean age of patients was 50.15±16.37 years. This study population was male dominant where 94 (67.14%) were males and 46 (32.86%) were females. Out of the total study population, 104 (74.3%) were survivors while 36 (25.7%) were non-survivors. Worse APACHE II score from 20 to 34 had a greater number of patients with left ventricular diastolic dysfunction. When the APACHE II score was correlated with the presence of LVDD in both survivors and non-survivors, it was observed that in the non-survivors as the APACHE II score worsens from 20 to 34, there was significant mortality as compared with the survivors. Conclusion: LVDD was present in patients above the age of 40 years. As the APACHE II score worsens from 20 to 34, a greater number of patients showed LVDD. When APACHE II score was correlated with presence of LVDD in both survivors and non-survivors, it was observed that in the non-survivors as the APACHE II score worsens from 20 to 34 and there was a significant mortality as compared with the survivors. EnglishSepsis, LVDD, APACHE IIhttp://ijcrr.com/abstract.php?article_id=2736http://ijcrr.com/article_html.php?did=2736

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareA Study on Correlation of Magnetic Resonance Imaging and Arthroscopy in Evaluation of Anterior Cruciate Ligament Injury in Cases of Acute Traumatic Haemarthrosis of Knee: A Prospective Study English1417Ankush MohabeyEnglish Suvarna GuptaEnglish Vasant GawandeEnglish Kunal SaojiEnglishBackground: Swelling and discomfort in acute knee injuries make knee clinical tests challenging and ineffective. Magnetic Resonance Imaging (MRI) could also be used to diagnose intra-articular and extra-articular traumatic lesions in the knee while Arthroscopy was the traditional gold diagnostic method for evaluating intra-articular knee injury. We proposed the study to evaluate the effectiveness of MRI in assessing the Anterior Cruciate Ligament injury in comparison to arthroscopy of the knee. Method: Study was undertaken in the Department of Orthopaedics, Datta Meghe Hospital, Nagpur in collaboration with Datta Meghe Hospital, Sawangi, India from August 2019 to March 2020 to ascertain the need for routine MRI of the knee for assessment of an injury of the anterior cruciate ligament in sudden traumatic haemarthrosis. 16 yrs to 60 yrs age were included and intra-articular fractures, patellar dislocations, extraarticular ligamentous lesion, previous injury to the same joint, non-haemorrhagic, and haemophilias were excluded. Results: 32 cases of acute traumatic haemarthrosis of the knee during the period from August 2019 to March 2020 were subjected to MRI examination and arthroscopic examination and findings noted on the scoring system based on The International Knee Documentation Committee (IKDC) 2000 scoring system. Total MRI positive ACL deficient patients were 18 out of 32 and total Arthroscopically positive ACL deficient patients were 13. 10 patients were ACL deficient both in MRI and Arthroscopically and 11 were having normal ACL both in MRI and Arthroscopic evaluation. Fisher exact test p= 0.0751 and Chi-square with Yates correction p= 0.1125. The sensitivity of MRI in detecting ACL injury is 76.92 in comparison to arthroscopy. In spite of the high sensitivity, the specificity of 57.89 shows there is a decreased probability of detecting true negatives. The positive predictive value is 55.55 and the negative predictive value is 78.51 with an accuracy of 65.62. Conclusion: The cost of MRI although reduced is significant in comparison to arthroscopy. MRI with a sensitivity of 76.92 has a high index of detecting true positives. The probability of detecting true negatives is low with high false negatives. Arthroscopy examination is superior to MRI in detecting ACL injuries from the comparison with significant P-value. EnglishHaemarthrosis, MRI, Arthroscopy, ACLhttp://ijcrr.com/abstract.php?article_id=2737http://ijcrr.com/article_html.php?did=2737

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareIsolation and Identification of Bacteria from Cell Phones of Health Care Workers from Central India English1821Anupam KakadeEnglish Nandkishor BankarEnglish Mangesh PadmawarEnglish Dhruba Hari ChandiEnglish Brij Raj SinghEnglish Dilip GodeEnglishIntroduction: The telecommunications market in India is currently the second-largest in the world. Cell phones have been shown to pose a health threat with tens of thousands of microbes residing on every square inch of the phone. It has been observed that pathogenic bacteria exist on around 40 percent of patient-related cell phones and about 20 percent of hospital staff-related mobile phones. Cell phones are difficult to clean and therefore have the potential for contamination with multiple bacterial agents. Doctors and health care workers (HCW) serving in intensive care units (ICUs) or operating units are widely exposed to deadly micro-organisms. HCWs often become carriers and may act as vectors and spread microorganisms wherever they are taken. Material And Method: A total of 60 HCW cell phones were tested for their bacterial contamination at Datta Meghe University of Medical Sciences. Consent was obtained from all persons whose mobile phones had been included in this study. Swabs were soaked in the tube containing peptone water. The cell phones analyzed were obtained at random from four departments: laboratory, Surgical Intensive Care Unit, surgical unit, and Operation theater T area. The specimen was obtained using a sterile cotton swab moistened with sterile peptone water. After 24 hours of incubation, plates were examined for the growth of microbial colonies. Results: A total of 60 mobile phones were included and samples were collected. This study enrolled the mobile phones of 15 (25%) nurses, 15 (25%) Doctors, 15 (25%) attendent, and 15 (25%) laboratory technicians. All cellphones were touch screens having back cover. Coagulase negative Staphylococci (CoNS) was isolated from 24 (40%) cellphones. Methicillin sensitive Staphylococcus aureus (MSSA) and Methicillin resistant Staphylococcus aureus (MRSA) were isolated from 21 (35%) and 15 (25%) cells respectively. Isolation of Diphtheroids, Coagulase negative Staphylococci (CoNS), Pseudomonas aeruginosa, Esherichia coli, Micrococci, Acinetobacter species and ESBL Klebsiella was 18(30%), 24(40.0%), 22 (36.6%), 7(11.7%), 11(18.3%), 5(8.3%), and 3(5.0%) respectively. Conclusion: Mobile phones can serve as a potential carrier for the nosocomial infection spread. Therefore regular screening of mobile phones, proper sterilization and hand hygiene is recommended for all health care workers. EnglishCell phone, Mobile, HCW, Microbial contaminationhttp://ijcrr.com/abstract.php?article_id=2738http://ijcrr.com/article_html.php?did=2738

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareEffect of Feminine Obesity on the Outcome of Oocyte in Subfertile Females English2224Anupama SawalEnglish Ujwal GajbeEnglish Brijraj SinghEnglish Akash MoreEnglish Nandkishor BankarEnglishIntroduction: Rising levels of obesity pose a public health problem globally. Approximately 1.6 billion adults were overweight by having (BMI 25-30 kg / m2) and 400 million (BMI > 30 kg / m2) in 2005 globally. In general, obese women have lowered oocyte production, lower developmental output, and poor clinical experiences while undergoing assisted reproductive (IVF) treatment. The aim of this study was to perform a preliminary assessment of the influence of BMI on quality oocyte outcome i.e. finally impact on IVF outcome in these patients and to provide data for future trials in this field. Aim and Objectives: To study the effectiveness of body mass index on oocyte quality in subfertile females. Materials and Methods: This study is done in Wardha test tube baby centre AVBRH (SAWANGI) WARDHA Relevant data on the demographics and treatment history of 40 subfertile female patient as well as the indications for IVF treatment were recorded. Observation and Result: Patient in 21-24 BMI group 80% of them found with increased metaphase II stage oocyte retrieval. In BMI group 25-29, 45% patients observed with increase in metaphase II oocyte. In the BMI group of 30-34 only one out of 6 patients observed with increased oocyte quality remaining 5 showed negative responses. Conclusion: Increase in BMI in ovulatory women may be inversely proportional to affect the outcome of treatment with ovulation induction and finally on the likelihood of pregnancy. EnglishBody Mass Index [BMI], IVF, Oocyte qualityhttp://ijcrr.com/abstract.php?article_id=2739http://ijcrr.com/article_html.php?did=2739

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareAdministration of Clonidin as Adjuvant to Infiltration Anaesthesia in Tympanoplasty Surgery English2529Ashok ChaudhariEnglish Amruta MankarEnglish Pratibha DeshmukhEnglish Sweety AgrawalEnglishAdjuvant to local anaesthesia increases the efficacy and the duration of the block. Inj Clonidine recently gaining more popularity as an adjuvant to local anaesthetic agents for neuraxial and peripheral nerve blocks. In this study, we compared two groups Lignocaine with adrenaline and lignocaine with clonidine in post auricular block in patients posted for tympanoplasty. 60 American Society of Anaesthesiologists ASA 1 and 2 patients posted for tympanoplasty were randomly allocated in 2 groups in which group A (control group) received 10ml solution of xylocaine with adrenaline (1:200,000 dilution) and 2ml of normal saline and group B (study group) received 10ml of adrenalized xylocaine with 30mcg of clonidine in 2 ml of normal saline. Total volume of drug is similar in both the groups. Hemodynamic variables, oxygen saturation, level of analgesia were monitored in the intraoperative period. Incidence of postoperative nausea, vomiting, duration of analgesia, and other side effects was monitored till 24 hours after surgery. Duration of the block was significantly prolonged in group B. visual analog scale VAS scores were significantly lower at all times in group B as compared to group A. From this study we conclude that when 30mcg clonidine added to Xylocaine for post auricular nerve block proved to be more effective in providing analgesia introperatively and also postoperatively up to 6 hours. Interestingly the incidence of post-operative nausea vomiting was also lower in the clonidine group although it has no effect on the onset of analgesia. EnglishEar surgeries, Hypotension, Ischemic heart disease, Diabetes mellitus, Bleeding disorderhttp://ijcrr.com/abstract.php?article_id=2740http://ijcrr.com/article_html.php?did=2740

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareOutcome of Distal End Clavicle Fractures Treated with Locking Plates English3034Ashwin ChauhanEnglish Vasant GawandeEnglish Kunal K SaojiEnglish Ankit MittalEnglish Suvarn GuptaEnglishBackground: Clavicle fractures are one of the commonest fractures with accounts of 3 % of all injuries. Lateral end clavicle fracture contributes 25% of clavicle fractures and out of that 10-52% is unstable which requires various surgical fixations for better functional outcome. The aim of our study is to find out functional outcome following surgical fixation with locking plates. Methods: It is the prospective study conducted at Shalinitai Meghe Hospital, Nagpur from June 2019 to April 2020 (11 months) in 66 patients admitted at our hospital for surgical management. Results: 66 patients aged from 18-40 years with a mean age group of 29 years with 44 patients were right-sided clavicle fractures. Meantime for trauma to surgery was 76 hours with a mean operative time of 60 min. The average time for bony union of fracture was noted to be around two and a half months. After 8 weeks and 24 weeks, the Mean DASH score was found to be 4.6 and 11.63, respectively. The functional results were Excellent in 24 (36.36%), Good in 40 (60.6%), Fair in 1 (1.51%), and Poor in 1 (1.51%) patients according to the DASH score. Conclusion: Though there are various surgical methods for fixing such unstable variety of lateral clavicle fracture, the gold standard treatment option is debatable and challenging. But we found in our study, the functional outcome after using a pre-contoured locking plate for such cases is beneficial and satisfactory. EnglishDistal end clavicle fracture, Unstable fracture, Pre contoured locking plate, Trauma, Neer's Classificationhttp://ijcrr.com/abstract.php?article_id=2741http://ijcrr.com/article_html.php?did=2741

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareA Comparative study of Disability and Pain Assessment by Shoulder Pain and Disability Index (SPADI) Score in Patients of Adhesive Capsulitis Treated by Hydrodilatation with and without Corticosteroids English3540Kunal K. SaojiEnglish Vasant GawandeEnglish Rajesh DulaniEnglishBackground: Adhesive Capsulitis is a painful condition commonly occurring in the middle age group population causing disability in the population and hence we conducted the present study with the aim to describe the pain and disability assessment in patients of adhesive capsulitis treated with and without injectable corticosteroids (hydrodilatation). Methodology: A prospective study was conducted from June 2018 to March 2020 for a period of 2 years, at a tertiary care hospital. The sample size included 40 patients with the diagnosis of adhesive capsulitis divided into 2 groups randomly. SPADI score was calculated and pEnglishAdhesive capsulitis, Saline, Steroid, Hydrodilatation, Disability, Painhttp://ijcrr.com/abstract.php?article_id=2742http://ijcrr.com/article_html.php?did=2742

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareRole of Zinc in Pulmonary Tuberculosis English4144Pradip JainEnglish Rakesh Kumar JhaEnglish Ranjit S. AmbadEnglish Archana DhokEnglish Prakash KuteEnglishIntroduction: Around the world, TB is among the main 10 reasons for decease and the main source from a solitary infectious agent (above HIV/AIDS). A large number of individuals keep on falling wiped out with Tuberculosis every year. In 2017, Tuberculosis caused an expected thirteen lakhs death (12 lakhs to 14 lakhs) among non-HIV individuals and there were an extra 300,000 passings from Tuberculosis (266,000–335,000) among HIV-constructive individuals. Aim: Role of Zn in Pulmonary Tuberculosis Material and Methods: The research included 50 patients of Pulmonary TB and 50 healthy subjects and sex-coordinated solid individuals as the benchmark group. This is a cross-sectional investigation wherein cases were out-patients with dynamic PTB patients (new sputum smear-positive) went to the Directly Observed Treatment Short-course focus in the Dept. of Pulmonary Medicine, DattaMeghe Medical college, SMHRC, Nagpur in collaboration with JNMC, ABVRH (DattaMeghe Institute of Medical Sciences Deemed To Be University), Sawangi, Wardha, Maharashtra. Conclusion: The present study evaluated a significant low level of serum Zn in active cases of pulmonary tuberculosis which is appreciated by clinicians as the normal level is essential to combat with the help of cell-mediated immunological response. In the normal subject, Zn has to be supplemented in our diet and can be given as preventive nutrients to increase cell immunity. EnglishZn, TB, HIV/AIDS, ATT and ESRhttp://ijcrr.com/abstract.php?article_id=2743http://ijcrr.com/article_html.php?did=2743

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareStatus of Vitamins and Minerals in Pregnancy: Still A Point of Concern in Central India English4549Mrunal NakadeEnglish Mugdha L JungariEnglish Ranjit AmbadEnglish Grishma DhingraEnglishGlobally, 1.62 billion people are affected by anemia, of which 56 million are pregnant women. Anaemia is a major public health issue that affects both developing and developed countries with severe implications for both human health and social and economic growth resulting in a loss of billions of dollars annually. During pregnancy, anemia is considered extreme when the concentration of hemoglobin is less than 7.0g / dL, moderate when-hemoglobin falls between7.0–9.9g / dL, and mild at 10.0-11g / dl. The study was conducted on pregnant womens, 230 pregnant women and 40 non pregnant women have taken part in the study. Out of 230 pregnant women, 140 women are having decreased concentration of Hb, Vit-B12, folate, ferritin and transferrin.The present study concludes thatadequate iron and Folic acid intake is necessary for a healthy pregnancy, iron, and Folic acid supplementation should be considered early in these cases at their first meeting with healthcare professionals. EnglishPregnancy, Anemia, Vitamin B12, Folic Acidhttp://ijcrr.com/abstract.php?article_id=2744http://ijcrr.com/article_html.php?did=2744

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareRole of Physiotherapist to Promote Physical Activity in Physical Therapy Settings: Questionnaire Study English5055Shweta A. PanchbudheEnglish Y Praveen KumarEnglish Sachin ChoudharyEnglish Anjalee ChiwhaneEnglishBackground: Physical inactivity is a major risk factor for chronic disease. Primary health care practitioners are well placed to promote a physically active lifestyle. The perceptions and practice of physical therapists on their role in physical activity promotion are not well known. Objectives: The aim of the study is to determine the promotion of physical activity in physical therapy settings and to know the attitude of the therapist towards physical activity in relation to patient. The objective of this study was to determine the knowledge, confidence, role perception, barriers, feasibility, and counseling practice of physical therapists and physical therapist students Materials and Methods: Physiotherapist both male and female within the age group of 25-34 years who are clinically practicing either in physiotherapy college or private clinics who are handling patients on day to day basis irrespective of type of patients handled will form the subjects for this study. Results: The first questions revealed that 61% of the therapist reportedly encouraged patients to have physical active lifestyle in almost about 6-9 patients, moreover none of the therapist answered the answers in never or rarely. 51% of the therapist agreed that taking stairs at work is enough physical active to improve wealth as shown. the results for half an hour of walking on most days is all the exercise that is needed for good health has been agreed by 54% of physiotherapist. Exercise that is good for health must make you puff and pant has been disagreed by 44% of the subjects and 10% have strongly disagreed. 44% have agreed from the survey that several short walks of 10 minutes is better than one round of long walk per week for good health. Discussing the benefits of physically active lifestyle with patients is a part of physical therapist role have been agreed by 81%. Suggesting patients ways to increase daily physical activity is a part of physical therapists role have been agreed by 83% of the subjects. Only 76% felt confident in giving general advice to patients on physically active lifestyle. 73% of subjects were agreed to feel confident in suggesting specific activity programmes for their patients. overwhelming 100% agreement was found for fact that physical therapist should be physically active to act as a role model for their patients of which 91% strongly agreed and 9% agreed. About own physical activity 54% felt much more active when compared with other Indians of same age and sex. 39% felt slightly more active and 7% about the same. none of them reported with slightly less active or much less active. Conclusion: It is concluded that physiotherapist are basically responsible for encouraging patient for having physically active and also suggest various measures to improve and enhances patients physical active ,therefore this study highlight tens the fact that physical therapy not only involves administration of physical exercise but includes advices and means of physical activity promotion. EnglishQuestionnaire, Physiotherapy students, Physical therapyhttp://ijcrr.com/abstract.php?article_id=2745http://ijcrr.com/article_html.php?did=2745

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareStudy of Microalbuminuria and Uric Acid in Type 2 Diabetes Mellitus English5665Prajakta WarjukarEnglish Pradip JainEnglish Prakash KuteEnglish Ashish AnjankarEnglish S.S. GhangaleEnglishIntroduction: A significant complication of diabetes mellitus is diabetic nephropathy. Microalbuminuria (30-300 mg/24 hour urinary albumin excretion) is an indicator of diabetic nephropathy in type II mellitus diabetes patients. Research has shown that the development of microalbuminuria with therapies to closely regulate blood sugar and blood pressure is reversible. Hyperuricemia represents an independent threat of renal dysfunction in diabetes mellitus (DM) patients. Hyperuricemia can lead to endothelial dysfunction and nitric oxide inhibition, which can cause insulin resistance and thus diabetes. Uric acid assessment is cost-effective, preventive, and has significant consequences for public health. Aim: To assess the significance of microalbuminuria and uric acid for early detection of kidney and cardiovascular involvement in type 2 Diabetes mellitus and early prevention its complications. Method: In this cross-sectional study, 100 diagnosed patients of type-2 Diabetes Mellitus were taken as cases and 100 age and sex-matched normal persons were taken as controls. Fasting plasma glucose (FPG), 2 hours postprandial glucose levels (2hPG), serum uric acid and serum creatinine, urinary microalbumin, urinary creatinine were analyzed in them. Urinary albumin creatinine ratio (ACR) was calculated. Result: In this study, it was seen that the prevalence of microalbuminuria was 37% in cases and 8% in control. Mean value of age, BMI, fasting glucose, post-meal plasma glucose, serum uric acid, microalbuminuria in patients of diabetes mellitus was found to be highly significant as compared to the control group (pEnglish: Microalbuminuria, Uric acid, Type 2 Diabetes mellitus, Creatinine, Nephropathyhttp://ijcrr.com/abstract.php?article_id=2746http://ijcrr.com/article_html.php?did=2746

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareIntrathecal Nalbuphine an Addition to Anaesthesia Armamentarium to Prolong Postoperative Analgesia English6670Pratibha DeshmukhEnglish Nikita DhumneEnglish Medha SangawarEnglish Vivek ChakoleEnglishBackground: Nalbuphine is a synthetic opioid. It has mixed agonist-antagonist action. When used as an adjuvant to intrathecal bupivacaine it acts on kappa receptors in the dorsal horn of the spinal cord producing analgesia. We aimed the present study to evaluate the effectiveness of intrathecal nalbuphine as an adjuvant. At the same time, the efficacy of nalbuphine for sensorimotor characteristics and postoperative analgesia was also judged. Method: A total of 100 patients were enrolled. They were randomly allocated into two equal groups. Group B: received 15 mg hyperbaric bupivacaine (3ml) 0.5% + 0.5ml normal saline and Group BN: received 15 mg hyperbaric bupivacaine (3ml) 0.5% + Inj. Nalbuphine 500μg (0.5ml). The sensorimotor characteristics, duration of effective analgesia, any hemodynamic alterations, and side effects were noted. Results: The sensory and motor block characteristics were significantly faster in group BN than group B. The duration of sensory and motor block, as well as duration of effective analgesia, was significantly prolonged in group BN in comparison with group B. Quality of analgesia during the procedure was excellent in 90% and 94% in group B and BN, respectively. Sedation score, hemodynamic parameters, and respiratory rate changes were comparable between both groups. In group B, 4% patient complained of nausea/vomiting, intraoperative hypotension noted in 4% and post-dural puncture headache was recorded in 1 patient while in group BN bradycardia was observed in 3 patients. Conclusion: Addition of 500μg of nalbuphine as an adjuvant to hyperbaric bupivacaine 0.5% for spinal anaesthesia provides excellent analgesia with a longer duration of effective analgesia in comparison to intrathecal hyperbaric bupivacaine 0.5% alone. EnglishNalbuphine, Opioid, Analgesia, Bupivacaine, Sensorimotor, Hypotension, Bradycardiahttp://ijcrr.com/abstract.php?article_id=2747http://ijcrr.com/article_html.php?did=2747

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareCorelation Between Cytological and Histological Grading of Breast Cancer and its Utility in Patient’s Management English7176Pratibha DawandeEnglish Neha BhattEnglish Obaid NomanEnglish Sweta BahadureEnglish Arvind BhakeEnglishBackground: The decision on neoadjuvant therapy is often supported by tissue examination for morphology and receptor status. However, core biopsy requiring more expertise, cost and time may not be a prefered choice by many. FNAC being a simple and easily available alternative needs to be explored for this purpose. Introduction: Breast cancer is the most common malignant tumor affecting females worldwide. With availability of better treatment options for managing these patients, the mortality assosiated with it has reduced considerably. In a country of limited resources like ours FNAC remains an easily available, cheap and less invasive modality that can be utilized not only in diagnosing malignancy but also in grading the tumors, which in turn will be useful in deciding neo adjuvanct therapy. Out of the various grading systems, Robinson’s grading system is simple and time saving and hence we have selected it to be corelated with Modified Bloom Richardson’s grading system. Material and Methods: A prospective study was carried out, wherein two independant observers subjected all breast cancer patients grading by cytological and histological examination of tissue and cyto histo correlation. Results: This study achieved good individual correlation and interobserver agreement on grading of cytopathological aspirates of breast cancers. Conclusion: Cytopathological grading would be beneficial to these patients and hence should be routinely incorporated in reporting. EnglishBreast cancer, Cytopathology, Robinson’s grading system, FNAChttp://ijcrr.com/abstract.php?article_id=2748http://ijcrr.com/article_html.php?did=2748

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareStudy of Induction of Labour with Oral Misoprostol and its Maternal and Perinatal Outcome English7781Priya Pratapan NairEnglish Mugdha L JungariEnglish Mahima R. TiwariEnglish Lata Kanyal ButolaEnglishBackground: One great challenge in obstetric care is labour induction. Oxytocin has been used for labor induction since very long, but with high rates of failed induction. Oral misoprostol as an induction of labour (IOL) agent is rapidly gaining popularity in resource-limited settings because it is cheap, stable at ambient temperatures, and logistically easier to administer compared to dinoprostone and oxytocin. We aim to investigate the safety and effectiveness of oral misoprostol for induction of labour in our hospital setup. Material and Methods: Women with a singleton pregnancy in cephalic presentation and an unfavorable cervix who gave written informed consent and were fitting in the inclusion criteria were administered oral misoprostol, commencing at 25 mcg oral once every 4 hours for maximum 6 doses. The primary outcomes studied were i) the proportion of women delivering vaginally within 24 h of oral misoprostol administration, and ii) maternal and perinatal outcomes following induction with misoprostol. A retrospective Study of the data collected from September 2019 till April 2020 at Shalini Meghe Hospital and Research Centre, Wanadongri, Hingna, Nagpur was conducted where 188 women who came under the criteria were induced with misoprostol and outcomes were measured in the form of rate of normal vaginal delivery, maternal complications, and neonatal outcomes. Results: Total 188 patients were studied retrospectively. Vaginal deliveries were obtained in 65.95% of patients within 24 hours of induction. The cesarean section rate was 34.04%. The common cause of induction of labour was postdate pregnancy 49.46%. The response of patients with low bishop’s score was less with more doses required with longer induction to delivery rate and more chances of cesarean section. Conclusion: The oral misoprostol regimen for IOL described in the present study is safe, effective, and logistically feasible to administer in a resource-limited setting. English Induction of labour, Misoprostol, Perinatal, Oxytocinhttp://ijcrr.com/abstract.php?article_id=2749http://ijcrr.com/article_html.php?did=2749

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareGarbhasanskara (The Prenatal Stimulation): Educating Mother as Well as Baby English8285Priya P. ChawleEnglish Bhagyashree ChaudhariEnglish Varsha AdhavEnglish Mugdha L. JunghariEnglish Harshala SharmaEnglishThe privilege of recreating life is the most wonderful thing women have got. With this precious gift, like the other side of coin big hurdles comes in her life with the state of pregnancy. It is difficult to get adjusted. And moreover, it is difficult for many women to accept the would be coming new life. And get prepared for him or her. Most of them are unknown from the ability of unborn baby’s brain growth. The unborn baby’s brain consequently our personalities emerge from the complex interplay between the genes we are born with and the experience we have. Research has confirmed that more than 60% of the baby’s brain growth occurs in the intrauterine stage, on this basis it can be concluded that Garbhasanskara i.e. Educating unborn baby is more essential than schooling. Which can be done with the different modalities of garbhasanskara. It is going to contribute to making the personality of the unborn baby which is ultimately contribute to making a good human being. English Pregnancy, Garbhasanskara, Prenatal stimulation, Fetal psychology, Yoga in pregnancyhttp://ijcrr.com/abstract.php?article_id=2750http://ijcrr.com/article_html.php?did=2750

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareClinical Spectrum of Obsessive-Compulsive Disorder in Patients From Central India English8691Ragini PatilEnglish Tushar PatilEnglish Vishal Kumar ShahEnglishIntroduction: Obsessive-Compulsive Disorder (OCD) is an important cause of psychiatric morbidity in India. It is often coexistent with other psychiatric disorders such as Schizophrenia. There is no study describing OCD clinical spectrum from Central India. Aims & Objectives: To determine the clinical spectrum of obsessive-compulsive symptoms/disorder, to study the type of obsessive-compulsive symptoms/disorder, and to evaluate demographic & phenomenological variables. Material & Methods: This was a prospective observational study in a tertiary teaching hospital. All patients presenting to the outpatient clinics or admitted to the ward were evaluated for symptoms of obsessive-compulsive disorder. All these patients who were drug naïve were selected after fulfilling the inclusion and exclusion criteria. The patients were enrolled after obtaining written informed consent. The severity of OCD was assessed on YBOCS and global severity and improvement was assessed using the CGI scale at 12 weeks follow-up. Results: We evaluated 105 patients, out of whom 26 patients had OCD/S. Thus the prevalence of OCD/S in our study was 24.7%. Patients were in the age range of 19-58 years, with nearly 51.4% patients being in the age range of 19-29 years, 21.9% in the age range of 30-39 years, and 40-49 years respectively and with only 4.7% being more than 50 years. Overall male: female ratio was 1.5:1. It was seen that 50-60% of the patients had achieved some form of education and nearly more than 50% patients had achieved a secondary and higher levels of education. The mean duration of symptoms was 33.69 months. Predominantly obsessional thoughts and ruminations were in 04 (15.4%); predominantly compulsive acts in 03 (11.5%); Mixed obsessional thoughts and acts in 19 (73.1%); Other obsessive-compulsive disorders in 0 (0%); Obsessive-compulsive disorder, unspecified in 0 (0%). Mixed OCD was seen in 19 (73.0%); predominantly obsessional in 4 (15.3%) and predominantly compulsive in 3 (11.5%) patients. Types of obsessions were: Aggressive Obsessions in 0 (0%); Contamination Obsessions in 14 (53.8%); Sexual Obsessions in 04 (15.4%); Hoarding / Saving Obsessions in 01 (3.8%); Religious Obsessions in 03 (11.5%); Obsessions with Need for Symmetry or Exactness in 01 (3.8%); Somatic Obsessions in 01 (3.8%) and Miscellaneous Obsessions in 02 (7.7%) cases. Types of compulsions were: Cleaning/Washing in 14 (53.8%); Checking in 04 (15.4%); Repeating in 04 (15.4%); Counting in 02 (7.7%); Ordering/ Arranging in 01 (3.8%); Hoarding/ Collecting in 0 (0%) and Miscellaneous compulsions were seen in 01 (3.8%) patients. At the end of 3 months then a statistically significant difference was noted on the YBOCS obsession score (t=12.359, pEnglish OCD, YBOCS, Obsessive-compulsive, ECAhttp://ijcrr.com/abstract.php?article_id=2751http://ijcrr.com/article_html.php?did=2751

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareBreast Carcinoma in Axillary Tail of Spence: A Rare Case Report English9295Rajesh DomkuntiEnglish Yashwant R. LamtureEnglish Avinash RinaitEnglish Dilip GodeEnglishBreast carcinoma is known to be one of the commonest malignant tumours among which Axillary breast cancer is a special individual that accounts for 0.1% to 2% of all cases of breast cancer. This is usually composed of poorly differentiated IDC with squamous or mesenchymal carcinoma areas sometimes. Axillary malignancy is difficult as there are many differential diagnoses that may require careful evaluation. This is a case report on Breast carcinoma of tail of Spence in axilla with skin involvement near nipple-areola complex whose histopathology was suggestive of infiltrating ductal carcinoma of axillary tail of Spence with mild dysplastic changes over right nipple-areola complex and high lymph node positivity (96.7%). Standard investigations like Ultrasonography of B/L Breast with Axilla and Tru-cut biopsy were done to reach the diagnosis of Intraductal Carcinoma (IDC) of the axillary tail. English Tru-cut biopsy, Ultrasonography, High lymph node positivity, Intraductal carcinoma of breasthttp://ijcrr.com/abstract.php?article_id=2752http://ijcrr.com/article_html.php?did=2752

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcarePrameha and Diabetes Mellitus English9698Rekha V ShindeEnglish Ashish P RanaEnglish Harshala RajurkarEnglish Meghali N KapleEnglishBackground: This paper review different approach about Prameha and Diabetes mellitus, its pathopysiology, and treatment principles. Also reveals whether we are treating patients or only Hyperglycemia. With some alteration of the definition, the attempt is made to reconcile the conflicting evidence with the current conceptual scheme. Aim: To reconcile the contradictory facts with the existing conceptual scheme of Ayurveda w.s.r. to Prameha and diabetes mellitus. Methodology: The data contents have to be classified as the pathophysiology of Prameha and its treatment principles, and interpreted in terms of the western system of Medicine. Such a comprehensive collection of data has made from Brihatrai and Laghutraisamhita. Structured as- Prameha as Error in metabolism. Drugs/ Kalpas indicated in Prameha and their significance. Myth and Facts about Prameha and Diabetes Mellitus. Results: Prameha is a metabolic disorder and it can be definitely cure by following Ayurvedic conducts as doing corrections in diet and lifestyle. Conclusions: 1. Prameha is a more broad term over Diabetes Mellitus. 2. Popular modern belief in treating hyperglycemia with hypoglycemic drugs is not followed in Ayurveda to treat Prameha. 3. Pramehas treatment may not be essentially mean to have hypoglycemic effects only. EnglishPrameha, Pathyapthya Dosha equilibrium, Diabetes mellitus, Blood Sugarhttp://ijcrr.com/abstract.php?article_id=2753http://ijcrr.com/article_html.php?did=2753

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareTo Compare the Effects of Maitland Mobilization with Conventional Physiotherapy in Adhesive Capsulitis English99102Samiksha SatheEnglish Sukhna Kaur KhuranaEnglish Umanjali DamkeEnglish Prerna V. AgrawalEnglishBackground: Adhesive capsulitis of shoulder affects from 2% to 3% of the general population and is seen commonly at age of 40-65 years. Adhesive Capsulitis is a syndrome defined as an idiopathic painful restriction of shoulder joint movement resulting in over-all restriction of the gleno-humeral joint. Aim: The aim was to compare the effect of Maitland mobilization as an intervention to conventional physiotherapy in patients with adhesive capsulitis on pain, ROM (flexion, abduction, external rotation, internal rotation) and Shoulder pain, and Disability Index (SPADI). Methods: The research design used was Randomised experimental study design. Thirty participants were allocated into two groups, participants with even serial number were allotted for conventional therapy group A and those with odd serial numbers were allotted for Maitland therapy group B. Conventional therapy protocol included Ultrasound to shoulder joint for 7 days and Shoulder Mobility Exercises which were given 1 session (20 repetitions) per day for 15 days. Maitland therapy protocol included Ultrasound to shoulder joint for 7 days and Maitland mobilisation technique and Shoulder Mobility Exercises which were given 1 session (20 repetitions) per day for 15 days. Pre and post intervention scores were measured in terms of NPRS, SPADI, and ROM of the shoulder joint. The Shoulder mobility exercises included full (available) ROM exercises for shoulder joint and capsular stretching exercises. Conclusion: On the basis of this study, it can be concluded that there is a more significant increase in ROM, and SPADI score and a significant decrease in pain on NPRS by Maitland mobilization therapy along with conventional therapy as compared to conventional physiotherapy alone. English Adhesive Capsulitis, Maitland’s Mobilization, SPADIhttp://ijcrr.com/abstract.php?article_id=2754http://ijcrr.com/article_html.php?did=2754

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareEfficacy of Tramadol in Comparision with Diclofenac in Ureteric Colic Patients Brought to a Medical College in Central India- A Prospective Observational Study English103109Shadma QuaziEnglish Varsha GajbhiyeEnglish Sharjeel KhanEnglish Shailesh NagpureEnglishObjective: 1. To estimate the amount of patient exposed to NSAID i.e. Diclofenac and opioid i.e. Tramadol and towhat extent drugs are properly used, overused. 2. Our thesis aimed to provide a comparative overview of NSAID's analgesic efficacy i.e. Diclofenac, i.e. Opioids Tramadol and aimed at evaluating which type of drug is ideally suited in our Emergency Department (ED) for pain relief in acute renal colic. Methods: The study was planned as a prospective observational study conducted in Ureteric colic Patients receiving analgesics Tramadol and diclofenac in their management. Diagnosis was established by non-contrast abdominal CT. Fifty patients were selected for the study, of which 28 were given Diclofenac and 22 Tramadol. Data was analysed by using Microsoft excel sheet and descriptive statistics. Results: Characteristics of patients such as average stone size and degree of hydronephrosis at the time of enrolment were close to those of previous investigations. Diclofenac was slightly more effective in minimizing pain intensity at 30 minutes as calculated on a 10 cm visual analog scale than Tramadol. A reduction in pain frequency of over 50 per cent was reported in 56 per cent of patients diagnosed with Diclofenac and 44 per cent of patients treated with Tramadol (P < 0.05). Further Tramadol community patients required analgesia for the release (pEnglish Ureteric colic, NSAIDs, Opioids, Analgesia, Emergency departmenthttp://ijcrr.com/abstract.php?article_id=2755http://ijcrr.com/article_html.php?did=2755

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareUse of PG-E 2 Gel for Cervical Ripening in Labour Induction English110113Snehal DeshmukhEnglish Mugdha L JungariEnglish Urvashi ShramaEnglishContinuing a woman's pregnancy allows her cervix to remain closed and strong, and her uterus to remain calm and not contracting. There is a need to reverse both of these conditions to initiate labour. Cervix includes a small smooth muscle and mainly connective tissue with collagen as its key component and it must ripen as it becomes soft and pliable. Prostaglandins play a significant role in the process of cervical maturation and labour initiation. Prostagladin E2 intracervical gel contains 0.5 mg of dinoprostone and induces collagen breakdown, dispersion, fluid absorption by stromal tissues and successful cervical maturation for labor induction when applied locally. Materials and Methods: 70 antenatal patients who fulfilled the inclusion criteria were studied. Group 1 had patients who required a single dose of PGE2 gel and group 2 had patients who required a second dose of PGE2 gel. Results and Observation: Group 1 had 56 patients requiring a single dose of dinoprostone gel and group 2 had 14 patients requiring a second dose of dinoprostone gel for induction. The common indication for induction of labour was postdatism (45.71 %), The mean bishop score at the time of induction was 1.9. The improvement in mean bishops score at 6 and 12 hours in group 2 is just 2 as compared to 7.02 in group 1, The overall mean induction delivery time was 21.45 hours. The incidence of normal delivery was 74.28% and caesarean section rate in our study was 21.45 %. The common complications that occurred were vomiting (7.14%), diarrhea (5.71 %). Conclusion: PGE2 GEL is a safe and effective method for the induction of labour. The success of induction depends upon the cervical status. It increases the chances of a vaginal delivery without increasing maternal and neonatal morbidity English PG-E2, Cervical ripening, Labour, Inductionhttp://ijcrr.com/abstract.php?article_id=2756http://ijcrr.com/article_html.php?did=2756

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareThe Effect of Intracameral Adrenaline Bolus Injection on Pupil Size, Pulse Rate and Blood Pressure During Small Incision Cataract Surgery English114118Sonal MuleyEnglish Chetan SaojiEnglish Sachin DaigavaneEnglishAim: Pupillary miosis during cataract surgery and irrigation and aspiration (I/A) is found to be a major cause of iris trauma, cortex retention, posterior capsule rent, vitreous loss, and even posterior nucleus dislocation. Adequate mydriasis is necessary for safe cataract surgery. Intracameral adrenaline bolus injection can help maintain mydriasis. We designed a prospective interventional study to assess the efficacy and safety of intracameral adrenaline bolus injection after nucleus delivery, as an adjunctive to preoperative topical mydriatics. Methods: Forty patients with cataract were divided into two groups: Study group and the control group. The study group (20 patients) received intracameral bolus preservative-free adrenaline injection in the dose of 0.1 cc of 1:5000 concentration after nucleus delivery. The diameter of the pupil was measured by surgical calipers before and after nucleus delivery, after injection of intracameral adrenaline in the study group and after IOL placement in both the groups. Pulse rate, systolic, and diastolic pressure were measured before and after the cataract surgery. Results: The mean pupil size in the study group after nucleus delivery was 5.33mm and 5.32mm??in the control group. A significant pupillary dilatation was observed in the study group 30 seconds after the injection of bolus dose of intracameral adrenaline. The mydriasis obtained in the study group (mean 7.67mm??) was significantly greater than the control group mean (pEnglish SICS, Intracameral, Adrenaline, Bolus, Cataract, Dilatation, Mydriasishttp://ijcrr.com/abstract.php?article_id=2757http://ijcrr.com/article_html.php?did=2757

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareRigid Nephroscope for Therapeutic Bronchoscopy: Our Experience of Emergency Bronchial Foreign Body Removal in 13 Pediatric Patients English119122Swati MaldhureEnglish Rohini GulhaneEnglish P.T. DeshmukhEnglish Ashish ChoudhrieEnglish Vivek ChakoleEnglishTracheo-bronchial foreign bodies in patients are considered to be life-threatening and need emergency management. They are commonly seen in the pediatric population which needs special attention. In hospital settings after primary measures, bronchoscopy using a flexible video bronchoscope or rigid bronchoscope is performed for diagnostic and therapeutic purposes. Here, we suggest the advantages of a rigid nephroscope over the above in the management of trachea-bronchial foreign bodies as per our experience. We managed to remove 13 pediatric bronchial foreign bodies using a rigid nephroscope more efficiently and with more ease using a nephroscope. English Nephroscope, Bronchoscope, Foreign bodyhttp://ijcrr.com/abstract.php?article_id=2758http://ijcrr.com/article_html.php?did=2758

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareHealthcare Setting and Methicillin Resistant Staphylococcus aureus English123128Vandana KubdeEnglish Gargi Dangre (Mudey)English Abhay MudeyEnglishMethicillin-resistant Staphylococcus aureus (MRSA) infection remains the ever-increasing health care problem. It brings a high rate of morbidity and mortality especially in immunocompromised and hospitalised patients. MRSA infection is most often severe due to the expression of virulence factors, toxins, and immune-modulatory gene products along with limited options for its treatment. MRSA in the healthcare settings is an emerging challenge. Exposure of healthcare personnel to the MRSA environment puts them at increased risk of acquiring the infection. Given the limited options for treatments, there is a need to cautious use the current treatments and quest for research and development of new anti-MRSA agents. For the prevention of MRSA infection in healthcare personnel, adequate implementation of infection and prevention strategies is essential in all healthcare settings. In this article, we discussed the epidemiology of MRSA, current and emerging treatment options along with infection control strategies in the healthcare settings. English MRSA, MSSA, Antibiotic resistance, Treatment, Prevention, Epidemiologyhttp://ijcrr.com/abstract.php?article_id=2759http://ijcrr.com/article_html.php?did=2759

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareEncasing the Encephalon: Enhancing Psychosocial Rehabilitation English129134Sweta Kale PisulkarEnglish Hetal PurohitEnglish Rohit MistryEnglish Chinmayee DahihandekarEnglish Sandeep IratwarEnglishCranial defects can be broadly classified as congenital and acquired defects. The occurrence of cranial injuries has increased tremendously and due to awareness amongst the population in concern to aesthetics requiring the skull reconstruction, rehabilitation of these defects has also increased in this modern age. Rehabilitation of these defects with prosthesis only acts as a protective shell but also improves the neurological status of the patient. These cranial defects require surgical correction or repair which is named as Cranioplasty. Its aim not merely lies in aesthetically rehabilitating the defect but mainly providing relief to the psychological problems but also improves the patient’s social acceptance and performances. With the evolving trends in leaps and bounds, newer biomedical tools technologies and materials are made available to the surgeons and the Prosthodontists for a better outcome in both aesthetics and functions. This article describes a series of case reports on restoring the defect along with the psychological confidence in the patients. One of the techniques using bone cement in combination with the poly-methyl methacrylate is used, which is the novelty of this case report series. The management team constituted of Prosthodontists and neurosurgeons, thereby improving his neurological status and cosmetics. English Cranioplasty, Titanium plates, Cranial reconstruction, Rehabilitationhttp://ijcrr.com/abstract.php?article_id=2760http://ijcrr.com/article_html.php?did=2760

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareRole of High Resolution Ultrasonography and Color Doppler in Evaluating and Distinguishing the Type of Inguinal Hernia English135140Tejas P. SadavarteEnglish Nikhil O. BansalEnglish Pankaj BanodeEnglish Mangesh PadmawarEnglishPurpose: This study was carried out to assess the accuracy of ultrasonography in diagnosing and distinguishing the type of inguinal hernia, so that its use could be justified in the imaging of occult hernia or equivocal clinical examination findings. Patients and Methods: This study included 64 patients with symptoms suggestive of inguinalhernia that prospectively underwent a blinded sonography examination of the inguinal region and found to have inguinal hernia on sonography as well, and who could be followed up till the surgical exploration. The findings of combined physical examination and high resolution ultrasonography were correlated with the intraoperative (surgical) findings. Results: Sixty-four patients with symptoms of either groin pain or palpable groin bulge underwent ultrasonography of bilateral groin region. Of these patients, 6 went on to have bilateral inguinal hernia repair bringing the study total to 70 groins.The sensitivity of physical examination for indirect inguinal hernia in this study was 82.22% with 72% specificity and 84.09% positive predictive value and 69.23% negative predictive value. The hernial sac and the Inferior Epigastric Artery were successfully identified on every color Doppler sonography examination. The sensitivity of color Doppler ultrasonography for indirect inguinal hernia was 93.33%, the specificity was 80%, the positive predictive value was 89.36% and the negative predictive value was 86.96%. The overall accuracy of clinical examination in identifying the type of hernia correctly (direct vs indirect) was 78.57% while that of ultrasonography examination was 88.57%. Conclusion: This study concludes that ultrasound with color Doppler sonography can accurately diagnose inguinal hernias and its type which justifies its use in the assessment of occult inguinal hernia and thereby allowing improved treatment planning. English Groin, Inguinal Hernia, Color Doppler Ultrasonography, Inferior Epigastric Artery (IEA)http://ijcrr.com/abstract.php?article_id=2761http://ijcrr.com/article_html.php?did=2761

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareUnderstanding Fibroadenoma Breast through the Entities Arbuda and Granthi: A Review Article English148152Varsha AdhavEnglish Pradip AdhavEnglish Priya P. ChawleEnglish Harshala RajurkarEnglish Bhagyashri ChaudhariEnglish Lata Kanyal ButolaEnglishMedical treatment for fibroadenoma is not available. Surgical excision is the only treatment available, but it has a higher risk of recurrence which has led to a strong focus on finding alternative preventive and cure therapies for fibroadenoma. Ancient trusted therapies such as Ayurveda play a significant role in bringing about integrative approaches. Two conditions described in Samhitas, granthi and arbuda are close to that of lump, but detailed breast-related descriptions of these diseases are not available in the classics of Ayurveda. We have therefore tried to equate this disease with the Ayurvedic entities; only to open the doors of a holistic approach in the management of fibroadenoma breast. EnglishFibroadenoma Breast, Arbud, Granthi, Stana, Mansajhttp://ijcrr.com/abstract.php?article_id=2793http://ijcrr.com/article_html.php?did=2793

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241Modern Therapeutics ApplicationsEnglishN2020July21HealthcareModern Therapeutics Applications English0101Suryakant NagtilakEnglishEnglishModern Therapeutics Applicationshttp://ijcrr.com/abstract.php?article_id=2795http://ijcrr.com/article_html.php?did=2795