International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 6(13), July, 2014

Pages: 58-63

Date of Publication: 12-Jul-2014


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STUDY OF VISUAL OUTCOME AND POSTOPERATIVE COMPLICATIONS IN SCLERAL FIXATED POSTERIOR CHAMBER INTRAOCULAR LENS IMPLANTATION

Author: Sangeetha T., Narendra P. Datti

Category: Healthcare

Abstract:Purpose: To assess the visual outcome and complications in patients after scleral fixated posterior chamber intraocular lens implantation. Materials and methods: This hospital based prospective study was conducted at R.L. Jalappa Hospital and Research Centre, Tamaka, Kolarbetween November 2011 and May 2013. Study included 50 patients fulfilling inclusion criteria. All cases were worked up according to the protocol.Andall patients underwent mandatory anterior vitrectomy followed by Ab \?externo scleral fixated posterior chamber intraocular lens implantation.10-0 Proline sutures were used for transscleral fixation of lens haptics. Patients were followed up at 1st day, 1st week, 1st month, 3rd month and 6th month. Postoperative evaluation included best corrected visual acuity, Slit lamp Biomicroscopy and Indirect ophthalmoscopic evaluation and Biomicroscopic assessment of macula. Results: Best corrected visual acuity improved in 28 (56%) patients in the range 6/6-6/12 while 18(36%) patients in the range 6/18-6/36. The most common complication observed were striaekeratopathy, iritis and secondary glaucoma; which subsided by two weeks with postoperative medications. Conclusion: Ab\?Externo scleral fixated posterior chamber intraocular lens was found to have stable implantation and a true posterior chamber location in eyes having no capsular or zonular support with a low intra and post-operative risk profile. This technique also showed favourable postoperative visual outcome in aphakic eyes.

Keywords: Aphakia, absence of capsule support, intraocular lens, AC-IOL, PC-IOL, Iris fixation, sclera fixation, secondary intraocular lensimplantation.

Full Text:

INTRODUCTION
Cataract surgery has become the most commonly performed intraocular procedure worldwide, with constantly improving outcomes. Planned extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens (PC-IOL) implantation became more widespread1 and is the “Gold Standard” procedure for managing cataracts. Refinements in surgical techniqueshave givenway to newer techniqueslike manual small incision cataract surgery and phacoemulsification with, inthe-bagPC-IOL implantation which have become the procedure of choice in the management of cataracts.The essential pre-requisite for PCIOLimplantationis the presence of adequate capsulozonular support and ideally the IOL is placed in the capsular bag, which affords stable fixation at a position closest to the nodal point of the eye. However, in the absence of this support it becomes a great challenge for a surgeon, who is faced with manydecisions including when to implant the intraocular lens and which type of intraocular lens should be implanted leaving the patient aphakic. Secondary IOL implantation provides favorable visual outcome offering superior visual rehabilitation in comparison to aphakic spectacles or contact lens, as these lenses have many advantages over both of these techniques.They permit a betterelimination of perceptual problemsand reduceimage size disparity. Hence secondary implantation of intraocular lenses has become the standard procedure in the aphakic eyes. Placing an anterior chamber intraocular lens in aphakics have been discouraged as it carries a high risk of postoperative complications like corneal endothelial damage, pupillary block glaucoma, hyphema, uveitis and cystoid macular edema. Another method where the intraocular lens was sutured to the iris resulted in iris chafing, uveitis and pupillary constriction2 . To avoid these complications and still achieve a posteriorly placed lens position, scleral fixation of posterior chamber intraocular lens to the ciliary sulcus which lies about 1.0mm posterior to limbus3,4, are commonly used which have good visual outcome and less complications.

MATERIALS AND METHODS
A two year prospective study was carried out between November 2011 and May 2013 on 50 aphakic patientsfulfilling the selection criteria after informed consent. All patients were analyzed for visual outcome and intra operative and postoperative complications of Scleral fixated posterior chamber intraocular lens implantation in aphakic eyes using the Modified four point AbExterno scleral fixation technique. Patients with Corneal pathology (degenerations and dystrophies), pathology of retina, macula and optic nerve, chronic uveitis, traumatic cataracts andbleeding disorders were excluded from this study. The patients were divided into following groups according to the nature of procedure required: 1. Primary scleral fixation of IOL. (Patients who had capsular rupture during cataract surgery.Eg: Hyper mature cataracts, pseudoexfoliation, subluxated/dislocated lens) 2. Secondary scleral fixation of IOL. (Patients wanting secondary implantation in aphakic eyes) A complete ocular examination was carried out which included theBest corrected visual acuity with aphakic correction, slit lamp biomicroscopic examination for corneal clarity (endothelial status), presence of synechiae, phacodonesis or frank subluxation / dislocation of lens, pseudoexfoliation in pupillary margins. Dilated evaluation of fundus periphery and biomicroscopic evaluation of macula was done with a+90 D lens, Gonioscopy with Goldmann three mirror for any evidence of PAS, recession or neovascularisation, Applanation tonometry, Keratometery, A-scan and IOL power calculation was done by SRK –2 formula. All patients were given systemic antibiotics (Tab Ciprofloxacin 500mg). On the day of surgery pupils were dilated adequately with 0.8% tropicamideand 5% or 10% phenylephrineeye drops every 10 minutes along with Flurbiprofen eye drops, one hour before surgery. Informed consent was taken and all patients underwent mandatory anterior vitrectomy followed by Ab –externo four point scleral fixated PC-IOL implantation under peribulbar anaesthesia by all operating surgeons. Postoperatively all patients recieved a course of topical antibiotic and steroid eye drops hourly followed by a tapering dose for 6 weeks along with Flurbiprofen eye drops 0.03% TID for 4 weeks. Systemic antibiotics Tab Ciprofloxacin 500 mg was given for 5 days postoperatively. Postoperatively the patient was evaluated on 1st day, 1stweek, 1st, 3rdand 6th month. The total duration of followup was 6 months. At each postoperative visit, the patients were subjected to the following examinations:

1. Best corrected visual acuity for distant and near. 2. Slit lamp evaluation. 3. Indirect ophthalmoscopic evaluation and biomicroscopic assessment of macula was performed. A careful noteof IOL stability and centration, suture relatedcomplications, postoperative reaction and cystoidmacular oedema were made and the compiled pre andpostoperative data analysed. The results were comparedwith previously published studies.

RESULTS
The study included 2(4%) patients in age group <50 years, 17 (34%)patients in the age group 51- 60 years, 27 (54% ) patients in the age group 61- 70 years, and 4 (8%) patients in the age group 71- 80 years. The average age of patients was 63.56 years and about 31 (62%) patients were above 60 years of age.There were 24(48%) males and 26(52%) females. Age and sex distribution is presented in table1. Out of 50 patients 15(30%) patients underwent primary scleral fixation of IOL due to reasons like PC rent, subluxated /dislocated lens, zonular dehiscence etc., and 35 (70%) patients underwent secondary scleral fixation due to postoperative aphakia. Twenty eight eyes (56%) had good vision in the range of 6/6 – 6/12, eighteen eyes (36%) had better vision in the range of 6/18 –6/24 and four (8%) eyes had vision in the range of 6/36 – CF. Postoperative visual acuity improved significantly. (P value = 0.0007) The most common early postoperative complications noticed were Iritis in 9 (18%) eyes followed by Secondary glaucoma in 8 (16%), Striaekeratopathy in 5 (10%) eyesand Hyphaema in 5 (10%) eyes.And the late complications were Cystoid macular edema in 5(10.1%) patients,Suture erosion in 3 (6%) eyes, Mild lens tilt/mild decentered IOL in 2 (4%) eyes, subluxated IOL in 1(2%) patient and persistent corneal edema in 1 (2%) eye. IOL tilt which occurred in 2 cases (4%) developed significant astigmatism in one case only. All the early complications resolved with postoperative medications over a period of 2 weeks. Hyphaema resolved within 3-7 days in all the cases. IOL tilt which occurred in 2 cases (4%) developed significant astigmatism (-1.5 D) in one case only.

DISCUSSION
Optical rehabilitation of aphakic patients presents a therapeutic challenge when the patient is unable to tolerate contact lenses for reduction of aniseikonia associated with aphakic glasses. Variable options available include, epikeratophakia, anterior chamber IOL implant, iris fixated intraocular lens and scleral fixated intraocular lens implantation. Among them scleral fixated IOL implant can provide minimum magnification of image as compared to other options.5,6 In this study 50 eyes of 50 patients were included. Twenty eight eyes (56%) had good vision in the range of 6/6 – 6/12. This was comparable with another study conducted by Zia ulMazhry et al (2010)7 in 50 patients. Their study showed BCVA of 6/6-6/9 in 25 (50%) eyes, 6/12-6/18 in 16 (32%) eyes,6/24-6/36 in 6(12%) eyes and 6/60 in 3(6%) eyes.Similarly, K.S. Chandrakanthet al8 and AzizurRahman et al (2011)9 reported improvement of postoperative BCVA of 6/9 in 18 eyes, 6/12 in 6 eyesand 29 eyes in the range 6/6-6/18 respectively. In this study the most common postoperative complication was Iritis in 9 (18%) eyes followed by Secondary glaucoma in 8 (16%), Striaekeratopathy in 5 (10%) eyesand Hyphaema in 5 (10%) eyes.Cystoid macular edema in 5(10%) patients, Suture erosion in 3 (6%) eyes, Mild lens tilt/mild decentered IOL in 2 (4%) eyes, subluxated IOL in 1(2%) patient and persistent corneal edema in 1 (2%) eye which is comparable to Azizur Rahman et. al. (2011) study.

Due to iris manipulation while scleral fixation of IOL we noticed mild iritis in 11 (22%) patients which was comparable with the results of Kwong et. al. and Kanigowska K.10 Our study was also comparable with study conducted by Mona et. al. as depicted in the table 7.

CONCLUSION
We studied the safety, efficacy and stability of scleral fixated PC-IOL with the Ab – Externo four point technique. More than 60% of the cases in our series achieved a postoperative visual acuity of 6/6-6/12. Only 2 of the cases developed IOL tilt which was attributed to lose sutures and slippage. But significant astigmatism was noted only in one case. And one patient had persistent corneal edema even at the end of sixth month follow up probably due secondary glaucoma. Thus we conclude that the Ab – Externo scleral fixated posterior chamber intraocular lens was found to have stableimplantation in eyes with inadequate or no capsular support, with a low intra and post-operative complications. This technique also showed favourable postoperative visual outcome in aphakic eyes.

References:

1. Apple D.J, Mamalis N, Loftfield K.et al. Complications of intraocular lenses. A historical and histopathological review. SurvOphthalmol, 1984; 29:1–54.

2. Evereklioglu C, H, Bekir NA,BorazanM,Zorlu F.Comparison of secondary implantation of flexible open loop anterior chamber and scleral fixated posterior chamber intraocular lenses. J Cataract Refract Surg. 2003; 29 (2):301-8.

3. Duffey R J, Holland, Agapitos P J, Lindstrom R L. Anatomic study of transcleral sutured intraocular lens implantation. Am J Opthalmol.1989; 108:300-9

4. Bergren R L. Four point fixation technique for suturing posterior chamber intraocular lens. Arch Ophthalmol.1994;12:1485-7

5. Bleckmann H, Kaczmarek U. Functional results of posterior chamber intraocular lens implantation with scleral fixation. J Cataract Refract surg. 1994;20:321-6

6. Rahman A, Bhutto I A, Bukhari S, Hassan M, NasirBhatti M. Visual outcome and complications in Ab-externo sclera fixation intraocular lens in aphakia. Pak J Ophthalmol 2011;(27):73-7

7. Zia UM, Wasif MK. Classification and Evaluation of Secondary Posterior Chamber IOL Implantation Scleral Fixation of IOL. Pak J Ophthalmol 2010, 26 (3): 148-153.

8. Chandrakanth K.S, Nirupama B. The functional results of posterior chamber intraocular lens with scleral-fixation: A one-year follow up analysis. 2007;19(4):386-90

9. Azizur R, Israr AB, Sadia B, Mazharul H et al. Visual outcome and complications in AbExterno Scleral Fixation IOL in Aphakia. Pak J Ophthalmol 2011; 27: 73-77.

10. Kanigowska K, Gralek M, Karczmarewicz B. [Transsclerally fixated intraocular artificial lenses in children-analysis of long-term postoperative complications]. KlinOczna.2007; 109:283-6.



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Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

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Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


Best Article Award

A study by Dorothy Ebere Adimora et al. entitled \"Remediation for Effects of Domestic Violence on Psychological well-being, Depression and Suicide among Women During COVID-19 Pandemic: A Cross-cultural Study of Nigeria and Spain\" is awarded Best Article of Vol 14 issue 23
A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
A study by Saurabh Suvidha entitled \"A Case of Mucoid Degeneration of Uterine Fibroid with Hydrosalphinx and Ovarian Cyst\" is awarded Best article of Vol 14 issue 21
A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
A study by Shafaque M. et al. entitled \"A Case-Control Study Performed in Karachi on Inflammatory Markers by Ciprofloxacin and CoAmoxicillin in Patients with Chronic Suppurative Otitis Media\" is awarded Best Article of Vol 14 issue 17
A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
A study by Singh R. et al. entitled \"A Prospective Study to Find the Association of Astigmatism in Patients of Vernal Keratoconjunctivitis (VKC) in a Tertiary Health Care Centre in India (Vindhya Region MP)\" is awarded Best Article for Vol 14 issue 15
A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
A Study by Mokhtar M Sh et al. entitled "Prevalence of Hospital Mortality of Critically Ill Elderly Patients" is awarded Best Article for Vol 14 issue 12
A Study by Vidya S. Bhat et al. entitled "Effect of an Indigenous Cleanser on the Microbial Biofilm on Acrylic Denture Base - A Pilot Study" is awarded Best Article for Vol 14 issue 11
A Study by Pandya S. et al. entitled "Acute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents" is awarded Best Article for Vol 14 issue 10
A Study by Muhammad Zaki et al. entitled "Effect of Hemoglobin Level on the Severity of Acute Bronchiolitis in Children: A Case-Control Study" is awarded Best Article for Vol 14 issue 09
A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
A Study by Zahoor Illahi Soomro et al. entitled "Functional Outcomes of Fracture Distal Radius after Fixation with Two Different Plates: A Retrospective Comparative Study" is awarded Best Article for Vol 14 issue 05
A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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Disclaimer: International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal.



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International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal

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