International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 14(8), April, 2022

Pages: 40-46

Date of Publication: 19-Apr-2022

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Soil Microbiota and Its Plant Interactions

Author: Domenico Prisa

Category: Healthcare

Abstract:Microbial biodiversity comprises microorganisms belonging to all kingdoms: from prokaryotes (archaea and bacteria) to eukaryotes (fungi, microalgae, molds, yeasts and protists). Microorganisms make up a large part of the earth's biomass, are extraordinarily diverse and are widespread in all habitats. More than two-thirds of the total biodiversity consists of bacteria, while archaea and eukaryotes occupy less than one-third. Microorganisms interact with each other and with the biotic and abiotic components of their environment, creating ecosystems in which there is a dynamic balance between the different components. The rhizosphere is the portion of soil surrounding the roots of plants, from which they absorb the essential nutrients and water they need to grow. In addition to the roots, there are further biotic components in the rhizosphere, such as symbiotic microorganisms, beneficial and pathogenic bacteria, and microscopic and macroscopic fungi. The aim of this review is to increase the knowledge about the interactions between plants and soil microorganisms.

Keywords: Sustainable agriculture, Microorganisms, Plants interaction, Soil research, Plant growth promoting rhizobacteria; Rhizosphere

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Since ancient times, some farmers have marvelled at how forests and grasslands could grow and vegetate without any fertilisation. Through long studies and after a long time we have been able to understand how this could happen. Much of what seems supernatural happens through a huge underground network of fungi and micro-organisms which, by interacting continuously, transfers and distributes large quantities of vital plant components such as nitrogen, phosphorus, manganese, sulphur as well as carbohydrates produced by plants.1 Among the major players in this, are arbuscular mycorrhizae, symbiotic associations established between thousands of species of soil fungi and the roots of most terrestrial plants. Mycorrhizae are essentially filaments (hyphae) that support themselves on the roots of the host plant and permeate the surrounding soil, progressively probing it for nutrients.2 Their combined action with a specific associated microbiome can extract key nutrients from the soil, store large amounts of carbon from the soil, retain and distribute water, buffer acidity and alkalinity and improve soil structure like no other. Unfortunately, some agronomic practices contribute to tearing apart this underground network with extremely negative results.3 The distribution of this natural resource through deep tillage, forced cultivation, uncontrolled fertilisation and long resting periods has led to the need to use mineral substances, which are obtained with enormous expenditure of energy, depletion of natural resources and non-renewable fossil fuels.4 One of the synthesis products of arbuscular mycorrhizae is glomalin, a glycoprotein containing 30-40% carbon. Glomalin is produced in large quantities by arbuscular mycorrhizal fungi (AM). In soils, the amount of glomalin was found to be correlated with the main fertility parameters. Laboratory analyses have shown that glomalin has a high affinity for iron and a strong ability to bind to heavy metals.5 Under normal conditions, these elements are used by the associated plant for its metabolic functions, whereas in seriously contaminated soils, glomalin effectively sequesters the metals from the soil and then transfers them to the host plant if the latter is able to tolerate them: the higher the tolerance of the host plant, the greater the quantity of elements extracted.6 Metal immobilisation of a highly stable protein fraction such as glomalin may be of considerable significance in alleviating toxicity due to excess metals. The metal contained GSRP (Glomalin Related Soil Protein) may represent a system to avoid the loss of metals contained in the soil through leaching and their percolation into groundwater. Glomalin, thanks to its long persistence period in the soil, would act in this sense as a trap system capable of storing mineral nutrients and immobilising them. Glomalin is capable of creating aggregates by promoting flocculation and storing carbon in the protein and carbohydrate (glucose and sugars) subunits of the soil, preventing leaching. It has been discovered that the weight of glomalin is 2 to 24 times that of humic acids (the products of plant decomposition hitherto considered to be most responsible for storing carbon in the soil). Humic acids would contribute only 8% of the soil carbon.2


The term microbiome is often mistakenly used to refer to the set of microorganisms that inhabit a living being or part of it. However, the correct term to use here is 'microbiota'. Instead, the microbiome refers to the totality of the genetic make-up possessed by the microbiota, i.e. the set of their genes.7 Almost all of us have been used to associating microbes and bacteria with a negative image since childhood. The 'bad' microbes that cause disease and infection are only a small part of the hidden world around us. Microbes are everywhere and not only live in close contact with us, but are indispensable for our survival and for the life of our entire ecosystem.8 Preserving the life and diversity of microorganisms is just as important as combating the 'bad' ones, just think of the beneficial effects that taking probiotics (good microorganisms) can have on our health. This is why the use of substances that can harm this 'invisible' population is counterproductive. Several studies correlate the microbiome with the health status of the host, making microbiome analysis a new frontier not only in medicine, but also in agriculture.9 Microorganisms can boost the immune system and prevent diseases, determine the productivity of soils and crops and thus improve growing conditions (Figure 1). Knowing the micro-organisms that colonise different soils and the relationship between the microbiome and the environment, which is strongly involved in the fate of ecosystems, is crucial in the interaction between plants and the land. Recent studies show that a strong correlation exists between the microbiome of the land and the microbiome of plants, resulting in an impact on food. Also in the food sector, the microbiome plays an important role in various productions, such as fermented products.10 The microbial biomass represents a reserve of available nutrients, so soils with a high microbial mass have a higher capacity to make them available. Enzymatic activity is the ability of a soil to stimulate certain spontaneous biochemical reactions in the soil. Some reactions occur faster (e.g. urea degradation) if the catalysts are enzymatic. Intracellular and extracellular enzymes are present. Intracellular enzymes within microbial cells are responsible for normal metabolism, while extracellular enzymes make certain compounds available to organisms that are otherwise unusable.11 The majority of enzymes in the soil are microbial in origin, so enzyme activity is an indicator of the presence of microorganisms in the soil. Micro-organisms interact with soil surfaces, so the greater the specific surface area, the greater the presence of micro-organisms.12 In clay soils their presence is greater. Enzyme activity is also influenced by crop rotation (a maize-oats rotation results in an average presence and persistence 2/3 times higher than a single-crop maize rotation), tillage (less tillage, higher content) and pH. Among the enzymes, dehydrogenase is the one most involved in the early stages of organic matter degradation, its presence depending on the biological activity of microbial populations.13


Micro-organisms can adversely affect plant development without necessarily acting as plant pests.14 Their action can alter the water supply, the uptake of ions and substances useful for growth, altering root functionality and/or limiting the harmonious development of the plant (Table 1). The main mechanism of action of the specific micro-organisms that improve the rhizosphere is competition with the harmful strains in the soil, thus favouring the availability and uptake of nutrients.15The various classifications of microorganisms in the rhizosphere distinguish between "major pathogens" and "minor pathogens", with the former penetrating the plant and causing the most damage, and the latter including obligate and facultative parasites.16 Within the minor pathogens there are some, non-psraxic, growth-altering with their metabolites (DRMO Deleterious Rhizosphere Microorganisms), while others are parasites of plant tissue (Parasitising Minor Pathogens).17 The pathogenicity of DRMOs is not easy to prove, as their effect on plants is limited to a delay in root growth without any other distinctive symptoms. The hypotheses that DRMOs belong mainly to different families, including Enterobacteriaceae, Corynebacteriaceae, Pseudomonaceae and Bacillaceae, are fairly consistent but not fully clarified.18


Microorganisms can interfere with plant growth through competition and interference with the microflora naturally present in the soil.19 Root growth, the length and number of root hairs and an efficient metabolism of the root cells are key aspects for an optimal uptake of water and less available ions in the soil such as P and K (Figure 2). There are micro-organisms that produce metabolites that hinder these processes and have a negative effect on plant growth.20 Others, such as Pseudomonas fluorescens, produce secondary metabolites such as growth-promoting substances and antibiotics. The action of metabolites can alter cell wall structure, cell permeability, polysaccharide and acid secretion and enzyme release, all of which interfere with physiological processes.21 We have to consider that for the plant the uptake of nutrients is an energy-intensive process and involves 60% of the root respiration under normal conditions.22 The increased availability or ease of uptake, assisted by specific micro-organisms, contributes to the availability of energy that the plant can use for other more useful metabolic activities (Table 2). Changing the composition of the microbiome also serves this purpose.23


The effectiveness of PGPR activity on stimulating plant growth depends mainly on the timely establishment and persistence of DRMOs.24 The greatest effectiveness is obtained by treating the seeds and tubers from which they will colonise the root systems (Figure 3). It has been noted that PGPRs introduced via this route remained during the growing season even though their numbers gradually decreased compared to the total (more stable) population of fluorescent Pseuodomonas.25Competition between micro-organisms increases as the overlap of their ecological niches increases. Some unfavourable environmental factors may reduce the effectiveness of PGPRs. The availability of Fe3+ is limited in alkaline and neutral soils and increases with increasing acidity. A higher activity of DRMOs and a lower suppressive activity of PGPRs on DRMOs could be expected as soil acidity increases.26 Some clay minerals appear to have a pronounced effect on siderophore-mediated microbial activity. For example, the presence or absence of certain clay minerals has been correlated with the suppressiveness of certain soil-borne diseases. The presence of illite inhibited the antagonistic activity of Pseudomonas fluorescens on root pathogens such as Thielaviopsis basicola, whereas this activity was favoured by vermiculite. The inhibition seems partly attributable to the interference of clay with the ferric nutrition of the fungi. The environment may also affect the rate of exudate emission by the roots and their composition.27


Phosphorus is a poorly mobile element in the soil and highly insoluble in non-neutral soils. Phosphorus is an essential element for plant development and is present in fair quantities in soils throughout Europe. However, it is always added to fertilisation plans because it is scarcely available to plants.28 However, this route is not sustainable given the limited availability of mineral phosphorus (stocks are expected to run out by 2033), the very low yield (only 5% of the added P is assimilated by plants) and the negative impact (e.g. eutrophication of water). Given the type of soil on the European continent, new solutions are being developed that are both environmentally sustainable and economically advantageous.29 The forms in which it is found in the soil are mainly phosphates (Fe, Al and Ca) or as gradually mineralised organic phosphorus. The reaction of the soil strongly influences its bioavailability: at a pH of less than 6, ferric phosphate prevails, and at a pH of more than 7, calcium phosphate, all stable and insoluble forms.Micro-organisms act on the breakdown of phosphorus organic compounds and the organification of mineral phosphorus. Mycorrhizae play a key role in phosphorus uptake by acting as root extensions and having high uptake efficiency even in more stable forms. Inorganic phosphorus present in the soil is transformed into soluble and available phosphorus by certain bacteria such as Pseudomonas fluorescens, Bacillus amyloliquefaciens and Bacillus megaterium. These bacteria are naturally present in our soils, but as they are sensitive to pollution and over-fertilisation, their presence is low if not absent in highly polluted soils.30 A solution could therefore be to multiply them in the laboratory and inoculate specific microbial consortia for each plant, thus overcoming the problem of pollution and natural competitors. Organic phosphorus is made available to plants by enzymes (phytase and phosphatase) present in certain endomycorrhizal fungi. Endomycorrhizae live on the roots of plants and a symbiosis is established between them and the plant. Some of them are capable of supplying phosphorus and water to the roots and in return take up carbohydrate substances.31 There are endomycorrhizae that release phosphorus quickly, others that take a long time, others that are able to release phosphorus constantly and finally there are endomycorrhizae that do not interact with phosphorus at all. Combinations of different types of mycorrhizae are optimal as they result in immediate availability of phosphorus that remains constant over time. The endomycorrhizae generally used are Glomus intraradices, Glomus claroideum, Gigaspora margarita. The limit in the use of mycorrhizae is given by the quantity of phosphorus already present in the soil, in fact for the symbiosis to be established there must be a convenience on both sides. If the plant has sufficient phosphorus (a condition which rarely occurs) it has no need to enter into symbiosis with the fungus.32Actinomycetes are also present in the soil. They perform an activity of fundamental importance, as they preside over various operations such as: i) active participation in the decomposition of animal and plant tissues resistant to microbial attack; ii) they allow the formation of humus, through the conversion of organic residues into compounds typical of the organic fraction of the soil; (iii) regulate the microbiological balance of the soil through the production of antibiotics and probiotics (group B vitamins) that stimulate growth.33


The effects of micro-organisms, irrespective of the quantity present in a given soil, appear to be influenced by the agronomic practices carried out in that soil. Numerous studies and observations have suggested that microbial factors, more than the presence of normal pathogens, play a decisive role in, for example, plant yield. Among these factors, non-spore farming of harmful microorganisms can play a decisive role.34 The effect on yield reduction increases in some species (potato) as the cropping sequence is intensified, although the mechanism generating this effect is not yet fully understood. The effect is certainly related to host specificity as in crops other than potato (wheat, beet) the effects are less evident. One of the explanations may be that some harmful strains survive on the root residues of the crop, representing a potential inoculum for the colonization of subsequent crops. As the frequency of cultivation increases, the phenomenon widens. Another hypothesis is the accumulation of compounds that stimulate the production of toxic metabolites. In the case of cyanide, glycine could be its precursor, as well as some ferric metals. Glycine and, to a lesser extent, proline, increase cyanide production by some microbial strains and both are constituents of radical exudates.35 Studies have shown that glycine is resistant to microbial degradation and that proline and glycylglycine have a high affinity for certain clay minerals, remaining in the soil for a long time. One of the possible causes of the disease known as replant disease (the reduction in vigor and reseeding yield of the same species) is attributable to fluorescent and non-fluorescent strains of Pseudomonas. There is therefore evidence that part of the microflora present in the rhizosphere can adversely affect plant growth and development and that the activity of this microflora is influenced by agronomic practices.5 Frequent tillage, especially deep tillage, has deleterious effects on soil microflora. In general, symbiotic microorganisms such as Rhizobium, some actinomycetes, mycorrhizal fungi and saprophytes increase the availability of nutrients and/or growth-stimulating substances as well as suppress parasitic and non-parasitic pathogens.10The inoculation of micro-organisms specific to the colonization of the rhizosphere can lead to extremely positive effects.36The production of siderophores under Fe-limiting conditions is one of the effects observed. This results in strong competition with harmful microorganisms for Fe3+ ions in the rhizosphere. Siderophores are small molecules with a high affinity for iron and capable of effectively chelating it, generally produced by certain microorganisms, fungi and grasses. Siderophores are among the strongest Fe3+ chelating agents known.37 The growth-promoting effect attributed to the removal of Fe available to harmful micro-organisms (DRMO) has been demonstrated in various experimental studies. Siderophores chelate Fe3+ that is no longer available to DRMOs, leading to a decrease in growth and virulence.38,39


In recent years, agriculture has faced the challenge of economic and environmental sustainability, reducing fertilizer use while adopting strategies to increase water use efficiency. Many microorganisms or fungi can promote the plant's use of nutrients and water in the soil.7 There are numerous bacterial strains that promote root growth and are classified according to acting at the level of the rhizosphere and rhizoplane. Many studies carried out with growth-promoting bacteria (PGPR), which have given interesting results in a controlled environment or in vitro, have not been as effective in field crops in promoting plant growth. One of the problems encountered in the field with the use of microbial biostimulants is the use of live microbial mediums which make application by the farmer difficult.5 To overcome this problem, microbial biostimulants are formulated and encapsulated with calcium alginate, which facilitates the retention and release of PGPR bacteria into the soil after application. Microorganisms that stimulate plant growth and resistance include arbuscular mycorrhizal fungi (AMF). They are effective in nutrient uptake but also in improving tolerance to abiotic stresses. One of the key characteristics of AMF is that they can only survive in symbiosis with the roots of the host plant. The improved quality of the plant in the nursery phase also has an impact on its behaviour in the subsequent cultivation phase. MFAs ensure a symbiotic relationship with the host plant, which makes it possible to overcome transplant stress and reduce the acclimatization period.15


As is well known, fertility depends on the physical, chemical and biological properties of the soil. However, biological soil fertility is often forgotten and is much less studied than the others. It is linked to the activity of micro-organisms, on which the balance of nutrient cycles such as nitrogen, phosphorus and sulphur depend. It is, therefore, necessary to investigate a number of aspects related to plant growth promotion such as: (i) how the action of DRMO siderophores on plant growth and field yield occurs and takes place; (ii) whether siderophores of PGPRs are produced in the rhizosphere; (iii) whether it is possible to genetically manipulate siderophores to increase the effectiveness of PGPRs.


The author would like to express his heartfelt gratitude to his colleagues at CREA Research Centre fr Vegetable and Ornamental Crops in Pescia and to all other sources for their cooperation and guidance in writing this article.

Source of Funding:


Conflict of Interest:

The author declares no conflict of interest.

Authors’ Contribution:

The author confirms sole responsibility for the following: study conception and design, data collection, analysis and interpretation of results, and manuscript preparation.



  1. Schippers B. Biological control of pathogens with rhizobacteria. Phil. Trans Royal Soc. Lond. 1988; 283-293

  2. Schippers B, Bakker AW, Bakker PAHM, van Peer R. Beneficial and deleterious effects of HCN-producing pseudomonads on rhizosphere interactions. Plant Soil 1990; 129:75-83

  3. Schippers B, Bakker AW, Bakker PAHM. Interactions of deleterious and beneficial rhizosphere microorganisms and the effect of cropping practices. Ann. Rev. Phytopatol. 1987; 25:339-358

  4. Schroth MN, Hancock JG. Disease suppressive soil and root colonizing bacteria. Science 1982; 216:1376-1381

  5. Somers E, Vanderleyden J, Srinivasan M. Rhizosphere bacterial signaling: a love parade beneath our feet. Crit. Rev. Microbiol. 2004; 30: 205-240

  6. Stroo HF, Elliott LF, Papendick RI. Growth, survival and toxin production of root-inhibitory pseudomonads on crop residues. Soil Biol. Biochem. 1988; 20:201-207

  7. Abatenh E, Gizaw B, Tsegaye Z, Wassie M. The role of microorganisms in bioremediation- A review. OJEB. 2017; 2:038-046

  8. Arora NK. Plant microbes symbiosis: Applied Facets. Springer India. 2015

  9. Bashan Y. Inoculants of plant growth-promoting bacteria for use in agriculture. Biotechnology advances. 1998; 16(4):729-770

  10. Bashan Y, de-Bashan LE, Prabhu SR, Hernandez JP. Advances in plant growth-promoting bacterial inoculant technology: formulations and practical perspectives (1998-2013). 2014; 378(1-2):1-33

  11. Baudoin E, Benizri E, Guckert A. Impact of artificial root exudates on the bacterial community structure in bulk soil and maize rhizosphere. Soil Biology and Biochemistry. 2003; 35(9):1183-1192

  12. Compant S, Samad A, Faist H, Sessitsch A. A review on the plant microbiome: Ecology, functions and emerging trends in microbial apllication. Journal of advanced research. 2019; 19:29-37

  13. Delgado-Baquerizo M, Oliverio AM, Brewer TE, Benavant-Gonzalez A, Eldrige DJ, Bardgett RD, et al.. A global atlas of the dominant bacteria found in soil. Science. 2018; 359(6373): 320-325

  14. Dennis PG, Miller AJ, Hirsch PR. Are root exudates more important than other sources of rhizodeposits in structuring rhizosphere bacterial communities? FEMS microbiology ecology. 2010; 72(3):313-327

  15. Dous S, Wang S. Review of different microorganisms effect on humus formation. Journal of Jilim Agricultural University. 2011; 33(2):119-125

  16. Foster RC. Microenvironments of soil microorganisms. Biology and fertility of soils. 1988; 6(3):189-203

  17. Gamalero E, Lingua G, Berta G, Glick BR. The beneficial role of plant growth-promoting bacteria and arbuscular mycorrhizal fungi on plant responses to heavy metal stress. Can. J. Microbiol. 2009; 55(5): 501-514

  18. Prisa D. Italian chabazitic-zeolitite and Effective microorganisms for the qualitative improvement of olive trees. Atti del Convegno di Calci (PI) 2017 Atti Soc. Tosc. Sci. Nat., Mem. 2018; 125:13-17

  19. Prisa D, Sarrocco S, Forti M, Burchi G, Vannacci G. Endophytic ability of Trichoderma spp. as inoculants for ornamental plants innovative substrates. IOBC Bullettin. 2013;86: 169-174

  20. Singh JS, Pandey VC, Singh DP. Efficient soil microorganisms: a new dimension for sustainable agriculture and environmental development. Agriculture, ecosystems & environment. 2011; 140(3-4): 339-353

  21. Souza RD, Ambrosini A, Passaglia LM. Plant growth-promoting bacteria as inoculants in agricultural soils. Genetic and molecular biology. 1987; 38(4):401-419

  22. Stevenson FJ. Humus chemistry: genesis, composition, reactions. John Wiley & Sons. 1994

  23. Toju H, Peay KG, Yamamichi M, Narisawa K, Hiruma K, Naito K, Yoshida K. Core microbiomes for sustainable agroecosystems. Nature plants. 2018; 4(5):247

  24.  Prisa D. Rhizobacteria and zeolites for overcoming saline stress in the cultivation of succulent plants.  The International Journal of Engineering and Science (IJES). 2019; 8(5I): 38-41

  25. Curtis TP, Sloan WT. Exploring microbial diversity- A vast below. Science. 2005; 309:1331-1333

  26. Ellingsoe P, Johnsen K. Influence of soil sample sizes on the assessment of bacterial community structure. Soil Biology and Biochemestry. 2002; 34(11):1701-1707

  27. Malusà E, Pinzari F, Canfora L. Efficacy of biofertilizers: challenges to improve crop production: In Microbial inoculants in sustainable agricultural productivity. Springer, New Delhi. 2016; 17-40

  28. Smith KA, Ball T, Conen F, Dobbie KE, Massheder J, Rey A. Exchange of greenhouse gases between soil and atmosphere: interactions of soil physical factors and biological processes. Eur. J. Soil Sci. 2018; 69(1):10-20

  29. Prisa D. Optimised fertilisation with zeolitites containing Plant Growth Promoting Rhizobacteria (PGPR) in Ranunculus asiaticus. GSC Biological and Pharmaceutical Sciences. 2020; 10(01):096–102

  30. Torsvik V, Ovreas L. Microbial diversity and function in soil: from genes to ecosystems. Current opinion in microbiology. 2002; 5(3):240-245

  31. Alexander M. Introduction to soil Microbiology. John Wiley & Sons, New York. 1977

  32. Briggs D, Walter SM. Plant Varation and evolution. Cambridge University Press. 1997

  33. Iaccarino M. Microrganismi benefici per le piante. Idelson- Gnocchi. 2006

  34. Prisa D. Gigaspora Margarita use to improve flower life in Notocactus and Gymnocalycium plants and roots protection against Fusarium sp. World Journal of Biology Pharmacy and Health Sciences(WJBPHS). 2020; 04(01), 051–058

  35. Prisa D. Improvement Quality and Content of Pepper and Chilli Nitrates Influenced by the Effective Microorganisms. American Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS). 2019; 53(1): 176-181

  36. Prisa D. Effect of Glomus mosseae inoculation on growth and flowering improvement of Chamaecereus sylvestrii and Mammillaria laui. World Journal of Advanced Research and Reviews(WJARR). 2019; 02(03):31-38.

  37. Prisa D. Glomus mossae and Glomus intraradices in the rooting and essential oil production of aromatic succulent plants Plectranthus amboinicus. Science International. 2022; 34(1): 41-44

  38. Prisa D. Effective Microorganisms Improve Growth and Minerals Content in the Medicinal Plant Bulbine frutescens. Indian Journal of Natural Sciences. 2022; 12(70): 37763-37770

  39. Florenzano G. Elementi di microbiologia del terreno. Manuali di Agraria. Edizioni Reda.1972


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A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award

A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award

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Disclaimer: International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal.


International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal


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