International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
logo
slider
slider
slider
slider
Bootstrap Slider

Indexed and Abstracted in: Crossref, CAS Abstracts, Publons, Google Scholar, Open J-Gate, ROAD, Indian Citation Index (ICI), ResearchGATE, Ulrich's Periodicals Directory, WorldCat (World's largest network of library content and services)

Search Articles

Track manuscript

Full Html

IJCRR - 13(19), October, 2021

Pages: 23-26

Date of Publication: 11-Oct-2021


Print Article   Download XML  Download PDF

Clinical Study of Scleral Fixated Posterior Chamber Intraocular Lens Implantation and its Morbidity

Author: Neha Maheshwari, B.S. Joshi, V H Karambelkar

Category: Healthcare

Abstract:Introduction: Secondary implantation of the intraocular lens in the posterior chamber is a safe and effective option for visual rehabilitation for cases with inadequate capsular support following cataract surgery, subluxation or anterior dislocation of lens following trauma, collagen vascular diseases or pseudoexfoliation. Aim: This study was done to analyze the visual outcomes and complications associated with scleral fixated intraocular lenses. MATERIAL AND METHOD- This prospective study was conducted in Krishna institute of medical sciences Karad from OCTOBER 2018- MAY 2020 for a period of 18 months.67 patients were included who were diagnosed with surgical aphakia, traumatic aphakia, subluxation of the lens and traumatic dislocation of the lens. All the patients underwent the Ab-external fixation technique of Scleral-fixated intraocular lenses (SFIOL) after informed consent. All the surgeries were performed by the same surgeon. The patients were followed up on the first day, one week, one month and three months after the surgical procedure and Best Corrected visual acuity and postoperative complications were noted. Results: Visual acuity at end of 3 months of follow up showed 74.62% cases had 6/9- 6/12 visual acuity and the remaining had visual acuity between 6/18-6/36 in 20.89% of cases and ≤ 6/60 in 4.48% cases. The immediate postoperative complications were: corneal oedema in 62.69%, followed by striate keratopathy in 11.94% cases, anterior uveitis among 2.99% cases, CME and raised IOP among 1.49% cases each. The late postoperative complication rate was reduced as compared to the early post-operative period. 68.66% had no postoperative complication after 12 weeks. The incidence of CME at the end of 12 weeks was 13.43%. 8.96% cases had raised IOP. Transient anterior uveitis was noted in 2 cases (2.99%). Retinal detachment (RD) was developed in 2.99% of cases. Conclusion: SFIOL is a safe and effective option in cases of inadequate posterior capsular support due to surgery or trauma, providing better visual rehabilitation with decreasing long term complication rates.

Keywords: Glaucoma, Intraocular lens, Posterior chamber, Cataract surgery, Retinal detachment, Ab-externo fixation technique

Full Text:

INTRODUCTION

Implantation of intraocular lenses is the standard procedure done in cataract surgery. Ideally, the lens is placed in the capsular bag (Posterior chamber intraocular lenses), which is close to the nodal point of the eye. However, there are instances where it is not possible to achieve in conditions like congenital (e.g., familial or idiopathic ectopia lentis, Marfan syndrome, etc) and secondary weakness of the lens zonules, type of cataract (e.g., traumatic cataracts with lens subluxation, cataracts in pseudoexfoliative syndrome with zonular/capsular dehiscence) or to intraoperative surgical complications (e.g., large breaks in the posterior capsule or posterior capsular rupture during cataract extraction, accidental aspiration of the capsular bag etc), trauma, lens dislocation, surgeons need to employ a technique to fixate an IOL without the support of capsule. Three principal alternatives for fixation are- 

1. Scleral suture-fixated posterior chamber intraocular lenses. (SFIOL).

2. Peripheral iris suture-fixated posterior chamber IOLs.

3. Anterior chamber intraocular lenses. (ACIOL).

Anterior chamber angle supported lenses are close to the cornea and anterior chamber angle, increasing the risk for bullous keratopathy, glaucoma, and peripheral anterior synechiae.1  In absence of capsular support, SFIOLs have become increasingly popular over the past decade. 2 Also SFIOL is an alternative to patients with complications of implanted ACIOL and those with contraindications to ACIOL and iris or angle-related abnormality.  In 1986, Malbran and co-authors first reported trans-scleral sulcus fixation of posterior chamber lenses in aphakic patients. 3

 Intraocular lens placement in the posterior chamber reduces the risk of various complications like bullous keratopathy, damage to anterior chamber angle, pupillary block glaucoma, iris chafing, hyphema, uveitis, and pseudo phacodonesis. 4

The surgical techniques which are explained for trans scleral sutures to fixate a posterior chamber intraocular lens are Ab interno (inside out) and ab externo (outside-in). 5,6  Ab- interno (inside out) technique involves the passage of sutures from the inside of the eye to the outside whereas the Ab-externo (outside-in) technique involves the passage of a suture from the outside of the eye to the inside. In the Ab-externo method, the intraocular lens placement occurs in the ciliary sulcus and the view of the surgical field is never obscured. The risk of vitreous haemorrhage decreases as all the manipulations occur in the iris plane. 7

MATERIALS AND METHODS

This prospective study was conducted in Krishna institute of medical sciences Karad from OCTOBER 2018- MAY 2020 for 18 months

INCLUSION CRITERIA-

   •Patients who underwent scleral fixation of posterior chamber intraocular lens (SFIOL) implantation in the Ophthalmology Department in Krishna hospital, Karad during the study period.

 EXCLUSION CRITERIA-

•All anterior segment pathology like central corneal opacity, glaucoma, uveitis etc. affecting the visual outcome.

•All Posterior segment pathologies affecting visual function like macular degeneration, chorioretinal atrophy etc., and complicating the surgery.

•All patients with manifestations of systemic diseases affecting the outcome of surgery.

•Patients who did not come for complete 3 month follow up period.

METHODOLOGY

Patients having a history of eye trauma with capsular bag rupture or complicated cataract surgery causing aphakia and those who completed 3 months follow-up were included in the study.

 A standard case proforma was maintained and a detailed clinical history was taken. PREOPERATIVE EVALUATION

1. Uncorrected and best-corrected visual acuity using Snellen’s distance and near visual acuity chart.

2. Slit-lamp biomicroscopic examination-

3. Measurement of IOP in all patients preoperatively.

4. FUNDUS EXAMINATION

5. IOL POWER CALCULATION - using SRK-T formula.

6. B scan and OCT done whenever required.

SURGICAL TECHNIQUE

All the surgeries were performed by the same surgeon. Anaesthesia and akinesia of globe obtained by peribulbar block with a mixture of 2% xylocaine with adrenaline with 2ml of 0.75 % bupivacaine with the addition of hyaluronidase were used. The skin around the eye is painted with 5% povidone-iodine and the same drops instilled topically.

1. After preparing the patient, a superior conjunctival peritomy from 4 o'clock to 10 o'clock position was created.

2. Partial-thickness triangular scleral flap of 3×2 mm at 4 and 10 o'clock positions created.

3. A 7 mm corneal scleral wound was made and a complete anterior vitrectomy was performed.

4. Anterior chamber and retro pupillary space were filled with viscoelastic substance.

5. Using a straight needle with 10-0 polypropylene suture was passed through one end of the sclera bed, 1 mm posterior to the surgical limbus and parallel to the iris until it was visualized through the pupil.

6. A 28 gauge hollow needle was passed through a 4 o'clock sclera bed was used to retrieve the straight needle, via its barrel.

7. Using a sinskey hook the loop of suture was retrieved through the corneoscleral wound.

8. After cutting the loop of the suture, it was tied to superior and inferior eyelets of the haptic of the IOL.

9. The IOL was placed in the sulcus and sutures were gently pulled to secure the position of the lens.

10. A second 10-0 polypropylene suture is used to take a bite just anterior to the original suture exit point in the scleral bed. The long end of the second polypropylene suture is tied to both its short end and the lens-fixing suture.

11. This was repeated at the other end of the scleral bed.

12. The scleral flap and conjunctival peritomy was closed.

Postoperatively patients were treated with topical Moxifloxacin 0.5 % + Dexamethasone 0.1 % eye drops 2 hourly which was gradually tapered.

POSTOPERATIVE EVALUATION-All patients were examined on the next day and were followed up after one week, one month and three months of the surgical procedure.

RESULTS

In the present study, we observed that the majority of the study subjects belonged to the age group of 56 to 65 years (47.76%), followed by 66 to 75 years (20.90%) then 46 to 50 years (14.93%).  . Majority of the study subjects were males (58.21%), while 40.30% subjects were females Right eye was affected among 52.24% study subjects, while the left eye was affected among 47.76% subjects.

The majority of the study subjects had preoperative BCVA as indicated in table 1 which was less than 6/60 (41.79%), followed by 6/24 among 38.81% subjects, 6/36 among 14.93% subjects and 6/18 among 4.48% subjects.

In table 2, Postoperative BCVA has been indicated which was less than 6/18 (32.84%), followed by 6/24 and 6/60among 20.90% subjects, 6/12 among 14.93% subjects and 6/36 among 10.45% subjects.

DISCUSSION

In the present study, all the patients (67) were selected for scleral fixation of posterior chamber intraocular lens (SFIOL) implantation. The mean age of the study subjects was57.39 ± 12.67 years. In the kwong et al. study the mean age of the patients was 76.7 years.8

Our study had 39 males and 27 females. The male to female ratio was 1:0.69. Regarding laterality, both eyes were almost equally affected (35 right eyes and 32 left eyes).

The most common diagnosis at presentation was post-surgical aphakia (65.67%) followed by the subluxated lens (19.41 %), traumatic subluxated lens (10.45%) and traumatic aphakia (5.98%). No studies have been found that included all the above inclusion criteria for SFIOL implantation.

In our study, all the post-surgical aphakia patients had undergone secondary procedures and all the traumatic patients had undergone primary procedures. In Lee et al study there were 30(54.5%) in the primary group and 25(45.5%) in the secondary SFIOL group8.In 39 patients the pre-operative visual acuity was between 6/36 to 6/18 and 28 patients had visual acuity of 6/60 and less. The mean duration of SFIOL implantation was 60 minutes. In Kwong et al. study the mean duration was 65min (SD±24.12 min).7,8,9

The Kh value pre-operative and post-operative was analyzed using the paired t-test and the p-value was significant (P = 0.0008). The analysis of Kv value pre-operatively and post-operative showed significant change and the p-value was significant (P= 0.00001). The mean pre-operative astigmatism was 1.29 ± 1.47, while the mean postoperative astigmatism was 1.76 ± 1.50. The analysis of mean corneal astigmatism pre and post-operative was found to be significant (p=0.00107).

Preoperatively, the majority of the cases had WTR astigmatism (43.28%), followed by ATR astigmatism (34.33%), OBL astigmatism (16.42%). Postoperatively we observed that 44.78% cases had WTR astigmatism, 32.84% cases had ATR astigmatism, and 13.43% had OBL astigmatism. The conversion of one type of astigmatism into another type was noted but the average percentage of the various types of corneal astigmatism has not altered much.

Postoperatively BCVA after 1 week was improved to6/9 – 6/ 12 among 46.27% cases followed by 6/18- 6/ 36 among 50.75 cases and≤ 6/60 observed among 20.99 % cases. At 12 weeks 74.62 cases had 6/9- 6/12 visual acuity and the remaining had visual acuity between 6/18-6/36 in 20.89% of cases and ≤ 6/60 in 4.48% cases. The improvement in visual acuity after 12 weeks of follow up is due to treatment of associated complications.

The immediate post-operative period was uneventful in 17.91% of cases. The immediate postoperative complications were: corneal oedema among 62.69%, followed by striate keratopathy among 11.94%, anterior uveitis among 2.99%, CME and raised IOP among 1.49% cases each.

 68.66% had no postoperative complication after 12 weeks. The incidence of CME and ERM at the end of 12 weeks was 13.43% and 1.49% respectively which were treated medically. These cases were associated with vitreous loss either at the initial event with the loss of capsular support or during scleral fixation. Another contributing factor for the development of CME is light-induced retinal injury due to the increased operating time.10

Increased IOP was noted in 6 cases (8.96%) for 1 week and was controlled with antiglaucoma drugs.11 While doing scleral fixation of IOL, transient anterior uveitis was noted in 2 cases (2.99%) which was treated with steroids and topical cycloplegics. 2 cases (2.99%) had developed Retinal detachment 3 months postoperatively due to too posterior placement of suture fixation and underwent RD surgery. None of the patients had major complications like endothelial decompensation, suprachoroidal or vitreous haemorrhage, dislocation of IOL/ IOL tilt or endophthalmitis.

CONCLUSION

In our study, we have noted that the rate of complications in the late postoperative period (>3 months after surgery) and found that the complication rate was reduced as compared to the early postoperative period. SFIOL to conclude is a safe and effective option in cases of inadequate posterior capsular support due to surgery or trauma, providing better visual rehabilitation with decreasing long term complication rates.

Acknowledgement: We acknowledge the contribution of our university and department for the unending support.

Conflict of Interest: There is no conflict of Interest 

Source of Funding: No Source of Funding

Authors Contribution: This is a collaborative work among all authors. Neha Maheshwari   B.S Joshi, V H Karambelkar, performed the statistical analysis, wrote the protocol, and wrote the first draft of the manuscript. Neha Maheshwari managed the literature searches. All the authors read and approved the final manuscript.

References:

1. Lorente R, de Rojas V, de Parga PV, Moreno C, Landaluce ML, Domínguez R, Lorente B. Management of late spontaneous in-the-bag intraocular lens dislocation: retrospective analysis of 45 cases. J Cataract Refract Surg. 2010 Aug 1;36(8):1270-82.

2. Peyman GA. Vitreoretinal surgical techniques. Routledge; 2019 Jul 12.

3. Malbran ES, Malbran E, Negri I. Lens guide suture for transport and fixation in secondary IOL implantation after intracapsular extraction. Int Ophthalmol. 1986 May 1;9(2-3):151-60.

4. Brunin G, Sajjad A, Kim EJ, de Oca IM, Weikert MP, Wang L, Koch DD, Al-Mohtaseb Z. Secondary intraocular lens implantation: complication rates, visual acuity, and refractive outcomes. J Cataract Refract Surg. 2017 Mar 1;43(3):369-76.

5. Can E, Ba?aran MR, Gül A. Scleral fixation of a single-piece multifocal intraocular lens. Eur J Ophthalmol. 2013 Mar;23(2):249-51.

6. Rau R, Santana CR, Martinez AA, Silva AL, Allemann N. Positioning of intraocular lens haptics intentionally implanted in the ciliary sulcus by ultrasound biomicroscopy. Arquivos brasileiros de oftalmologia. 2013 Jun;76(3):147-51.

7. Seki M, Yamamoto S, Abe H, Fukuchi T. Modified ab externo method for introducing 2 polypropylene loops for scleral suture fixation of intraocular lenses. J Cataract Refract Surg. 2013 Sep 1;39(9):1291-6.

8. Kwong YY, Yuen HK, Lam RF, Lee VY, Rao SK, Lam DS. Comparison of outcomes of primary scleral-fixated versus primary anterior chamber intraocular lens implantation in complicated cataract surgeries. Ophth. 2007 Jan 1; 114(1):80-5.

9. Chan TC, Lam JK, Jhanji V, Li EY. Comparison of outcomes of primary anterior chamber versus secondary scleral-fixated intraocular lens implantation in complicated cataract surgeries.      Am. J. Ophthalmol. 2015 Feb 1; 159(2):221-6.

10. Ceballos EM, Parrish II RK, Schiffman JC. The outcome of Baerveldt glaucoma drainage implants for the treatment of uveitic glaucoma. Ophthalm. 2002 Dec 1; 109(12):2256-60.

11. Collins JF, Gaster RN, Krol WF, Colling CL, Kirk GF, Smith TJ, VA Cooperative Cataract Study Group. A comparison of the anterior chamber and posterior chamber intraocular lenses after the vitreous presentation during cataract surgery: the Department of Veterans Affairs Cooperative Cataract Study. Am. J. Ophthalmol.. 2003 Jul 1;136(1):1-9.

Announcements

Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

COPE guidelines for Reviewers

SCOPUS indexing: 2014, 2019 to 2021


Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


Best Article Award

A study by Dorothy Ebere Adimora et al. entitled \"Remediation for Effects of Domestic Violence on Psychological well-being, Depression and Suicide among Women During COVID-19 Pandemic: A Cross-cultural Study of Nigeria and Spain\" is awarded Best Article of Vol 14 issue 23
A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
A study by Saurabh Suvidha entitled \"A Case of Mucoid Degeneration of Uterine Fibroid with Hydrosalphinx and Ovarian Cyst\" is awarded Best article of Vol 14 issue 21
A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
A study by Shafaque M. et al. entitled \"A Case-Control Study Performed in Karachi on Inflammatory Markers by Ciprofloxacin and CoAmoxicillin in Patients with Chronic Suppurative Otitis Media\" is awarded Best Article of Vol 14 issue 17
A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
A study by Singh R. et al. entitled \"A Prospective Study to Find the Association of Astigmatism in Patients of Vernal Keratoconjunctivitis (VKC) in a Tertiary Health Care Centre in India (Vindhya Region MP)\" is awarded Best Article for Vol 14 issue 15
A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
A Study by Mokhtar M Sh et al. entitled "Prevalence of Hospital Mortality of Critically Ill Elderly Patients" is awarded Best Article for Vol 14 issue 12
A Study by Vidya S. Bhat et al. entitled "Effect of an Indigenous Cleanser on the Microbial Biofilm on Acrylic Denture Base - A Pilot Study" is awarded Best Article for Vol 14 issue 11
A Study by Pandya S. et al. entitled "Acute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents" is awarded Best Article for Vol 14 issue 10
A Study by Muhammad Zaki et al. entitled "Effect of Hemoglobin Level on the Severity of Acute Bronchiolitis in Children: A Case-Control Study" is awarded Best Article for Vol 14 issue 09
A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
A Study by Zahoor Illahi Soomro et al. entitled "Functional Outcomes of Fracture Distal Radius after Fixation with Two Different Plates: A Retrospective Comparative Study" is awarded Best Article for Vol 14 issue 05
A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


RSS feed

Indexed and Abstracted in


Antiplagiarism Policy: IJCRR strongly condemn and discourage practice of plagiarism. All received manuscripts have to pass through "Plagiarism Detection Software" test before Toto Macau forwarding for peer review. We consider "Plagiarism is a crime"

IJCRR Code of Conduct: To achieve a high standard of publication, we adopt Good Publishing Practices (updated in 2022) which are inspired by guidelines provided by Committee on Publication Ethics (COPE), Open Access Scholarly Publishers Association (OASPA) and International Committee of Medical Journal Editors (ICMJE)

Disclaimer: International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal.



ABOUT US

International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal

Contact

148, IMSR Building, Ayurvedic Layout,
        Near NIT Complex, Sakkardara,
        Nagpur-24, Maharashtra State, India

editor@ijcrr.com

editor.ijcrr@gmail.com


Copyright © 2024 IJCRR. Specialized online journals by ubijournal .Website by Ubitech solutions