International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 13(16), August, 2021

Pages: 84-87

Date of Publication: 30-Aug-2021


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Customized Gingival Retraction Cord using Additive Manufacturing: A Novel Technique

Author: A. Hemavardhini, V. Vidyashree Nandini, Mathivathani S P, Shiney Boruah

Category: Healthcare

Abstract:Introduction: In Prosthodontics, impressions are required to produce indirect restorations with accurate fit. The main objective of impressions for fixed dental prostheses is to displace the gingival tissue and register the finish lines and prepared abutments accurately. To acquire preventive therapeutic, and aesthetic properties, the margins of restoration are accurately positioned in the prepared finish line of the abutment. In tooth-supported and implant-supported fixed prostheses, impression making requires an accurate record of the prepared finish line area, particularly where the finish line is located at the same level as gingiva or sub-gingiva. The Gingival retraction can cause tissue injury, bleeding, apical recession when proper positioning and minimal force application are not followed. Ideally, the retraction technique choice must be simple, quick, and inexpensive and should not cause damage to periodontal tissues. This article is an attempt to present the technique that involves the fabrication of a customized gingival cuff for abutment tooth by 3D printing technology using thermoplastic polyurethane material. Aim: The primary goal of this technique is to reversibly displace the gingival tissues such that an adequate amount of lowviscosity impression material can be introduced into the widened sulcus and records the marginal detail. Result: The customized 3D printed gingival cuff was packed into the gingival sulcus using a cord packer facilitated easy gingival retraction without damaging the surrounding gingival tissue. Conclusion: This technique greatly reduces the marginal discrepancy of the final restoration with minimal trauma to the gingival tissues and achieve a desirable emergence profile of the restoration especially when the finish line is at, or just within, the gingival sulcus

Keywords: Impression making, Finish line, Marginal discrepancy, Gingival retraction, 3D printing, Polyurethane material

Full Text:

INTRODUCTION:

The success of fixed dental prostheses depends on various factors like selection of material, ideal design, the technique of impression and maintenance of proper oral hygiene. The accurate finish line geometry plays a major role in the survival of the restoration. This will be accomplished by proper retraction of the gingival tissue surrounding the prepared tooth. The retraction of gingiva is a method of deflecting the gingival tissues away from the tooth and helps in proper recording of finish line of the abutment. Retraction of the gingiva will produce horizontal and vertical space around the prepared finish line facilitating ample of space for the introduction of impression material.The precise recording of the finish line geometry will achieve good marginal adaptation along with better durability as well as the success of the restoration. The gingival displacement technique has been categorized as, chemical, mechanical, surgical and a combination of the above.2 Most commonly employed technique is a chemico-mechanical method, in which retraction cords are used with hemostatic agent2,3In mechanical or chemical-mechanical method the implementation of retraction cord on the prepared tooth is well known in practice compared with rotary gingival curettage and electrosurgery because of the irrelative predictability, success, and safety.4 In order to achieve effective gingival displacement, a cord of adequate thickness can be used to retract the gingiva so that sufficient amount of impression material can be introduced in to the gingival sulcus. The larger diameter cord that causes minimal trauma while placing in the gingival sulcus should be used. A common error of inexperienced dental practitioners is using a small diameter gingival cord. Although these cords cause less trauma, they do not provide sufficient gingival displacement of the gingival tissues.5Redesigning the retraction cord and application of the minimum force can easily over the drawbacks of using the retraction cord technique.

The main aim of the technique is to fabricate a customized mechanical gingival retraction cord for abutment tooth by 3D printing technology which acts as an alternative to the conventional mechanical gingival retraction method. Various dental products are fabricated by Additive manufacturing which acts as a potentially useful technique. Of the various 3D printing technology available, the Fused deposition modeling printer is a robotic glue gun; an extruder moves over a stationary platform or vise versa.6 The software slices objects into various layers and transfers the coordinates to the printer. Thermoplastic materials must be used. Biodegradable polymer polylactic acid is the most commonly used material. Similar materials have also been used as scaffold structures for ‘bioprinting.7Thermoplastic polyurethane is widely made available as biomaterials in the field of medical science for fabricating various medical devices.

The Gingival cuff designed here is a customized 3D printed one using thermoplastic polyurethane material to facilitate a simple, inexpensive and easy gingival retraction method without damaging the surrounding gingival tissue.

The proposed technique was approved by the Institutional Scientific and Ethical Review Board and prior approval was procured before the commencement of the study (IEC approval:1475/IEC/2018).

TECHNIQUE:                                                                          

1. Measure and record the dimension of the gingival sulcus of the tooth to be prepared using William’s Periodontal Probe by inserting it parallel to the long axis of the tooth and move along the tooth. The sulcus depth is measured from the deepest point of penetration to the free gingival margin. (FIG-1)

2. Obtain upper and lower diagnostic impression.

3. Measure the bucco-lingual and mesio-distal width of the tooth to be prepared from diagnostic cast of the patient using digital Vernier calliper.(FIG-2,3)

4. The recorded measurements are loaded in the CAD designing software (CATIA V5-[Part1.CATPart]) (FIG-4).The CAD designing of the gingival cuff is done with the following measurement :

      • The Inner diameter of the cuff: Mesiodistal and labiolingual diameter of the tooth

      • The height of the cuff: Gingival sulcular depth of respective tooth

      • The angulation for the outside slanter: 2o

                    Finally, which makes it a shape sketch design.

5. Print the retraction cord in the 3D printing machine (Ultimakersophie, Model no. ULTIMAKER 3P03, Brand-IMIK, Utrecht Netherlands.) using 0.2mm nozzle size and material used being thermoplastic polyurethane material. (FIG-5,6)

6. After tooth preparation, insert the customized gingival retraction cord using a cord packer, tack the cord in the sulcus from the mesial side of the tooth to distal crevice and retain it in the sulcus for 3-4min.(FIG-7)

7.The 3D printed cord is removed from the gingival sulcus and an elastomeric impression is obtained.

In comparison with the existing commercial gingival retraction cords this customized gingival retraction cord by 3d printing technology is advantageous in terms of time, manipulation of gingival tissue, controlling of bleeding and is very cost-effective. It even controls the thickness of the cord, so that it can deliver a constant amount of force on to the gingival tissue.

Discussion:

The purpose of this technique was to analyse the impact of the gingival displacement on the marginal fit of a restoration. A properly fit restoration prevents the damage of the periodontium.3Gingival tissues are sensitive to mechanical or chemical trauma.8 The main drawback of the chemical-mechanical method is the rapid collapse of sulcus after removal which prevent accurate impression making, Trauma to epithelial attachment, is Time-consuming, Risk of sulcus contamination, Painful.1In the conventional method, the amount of displacement takes time and most of the time it leads to trauma of the gingival tissue because the operator is not aware of the sulcular anatomy. Many studies have described the use of knitted or braided, impregnated or unimpregnated strings or fibers of different materials as a mechanical gingival displacement method.4The unique knitted design of the retraction cord can exert a gentle, constant outward force following placement, and as the knitted loops try to open, it dilates the free gingival margin.9Some of the drawbacks reported can be listed as the traumatic injury to the gingival tissue by slippage of the instrument or excessive packing force during packing eventually resulting in gingival recession. Mechanical compression built up in the sulcular area limits the GCF flow but once the cord is removed rebound increase in GCF flow can occur compromising moisture control. In this technique the sulcular anatomy is pre-measured and based on the readings the 3D cuff is designed digitally and fabricated to occupy the exact form and shape of the gingival sulcus. This will prevent compression and trauma to the gingival tissue thereby helps in achieving the desired displacement aiding in finish line exposure. Additive manufacturing or 3d printing according to the American Society for Testing and Materials (ASTM) is the process of joining materials to make objects from 3D model data, usually layer upon layer, as opposed to subtractive manufacturing methodologies.6The material used thermoplastic polyurethane, is a biocompatible material with good abrasion resistance and tear resistance, so the chances of tearing during placing it into the sulcus is less and it is cost effective.10 Thermoplastic polyurethane (TPU) are linear, segmented block copolymers with excellent properties such as durability, flexibility, elasticity, biostability fatigue resistant, and insulating properties. These polyurethanes have a vital role in developing many medical devices such as catheters, endotracheal tubes, blood bags, drug delivery vehicles, heart pacemakers connectors, orthopedic splints, vascular grafts and patches.11 Because of non-thrombogenic characteristics polyurethanes are used in cardiovascular areas.12 TPU comprises of hard and soft segments.13Diisocyanide and short-chain extender molecules like diols or diamines are used to manufacture the hard segments. The high interchain interactiveness of hard segments is due to the hydrogen bonds and even acts as reinforcing fillers for the soft matrix. On the contrary, soft segments which have long, linear flexible polyether or polyester facilitates the interconnecting of two hard segments. Hard segments differ from soft segments in terms of rigidity and polarity.14 TPU is a biocompatible material with good abrasion performance; high tear propagation resistance; high damping power; and high resistance to oils, fats, and many solvents.15

Limitations of the study:

  • The amount of gingival retraction obtained is not quantified.

  • It requires an in-office 3D printer.

  • The incorporation of hemostatic agents can be employed in future studies.

Conclusion :

This article described a customize gingival retraction cord fabricated using 3D printing technology which aids as an alternative to the conventional gingival retraction method with improved properties in term of feasibility and compatibility. The gingival retraction technique is easy and safe to use. Thus, the newly advanced technique have been found to be cost-effective and even controls the thickness of the cord, so that it can deliver a constant amount of force onto the gingival tissue.

Conflict of interest:

No potential conflict of interest with respect to the research, authorship and/or publication of this article.

Funding:

No financial support received for the research, authorship and/or publication of this article.

Acknowledgement:

The authors acknowledge the support provided by Mr. Kalaiselvan for printing the retraction cords

References:

  1. Safari S, Vossoghisheshkalani Ma ,Vossoghi Sheshkalani Mi, Hoseinni Ghavam F, Hamedi M. Gingival Retraction Methods for Fabrication of Fixed Partial Denture: Literature Review. J Dent Biomater. 2016;3(2):205-213.

  2. Phatale S, Marawar PP, Byakod G, Lagdive SB, Kalburge JV. Effect of retraction materials on gingival health: A histopathological study. J Indian SocPeriodontol. 2010;14(1):35-39.

  3. Wostmann B, Rehmann P, Trost D, Balkenhol M. Effect of different retraction and impression techniques on the marginal fit of crowns. J Dent. 2008;36(7):508-512.

  4. Anupam P, Namratha N, Vibha S, Anandakrishna GN, Shally K, Singh A. Efficacy of two gingival retraction systems on lateral gingival displacement: A prospective clinical study. J Oral BiolCraniofac Res. 2013;3(2):68-72.

  5. Donovan TE, Chee WW. Current concepts in gingival displacement. Dent Clin North Am. 2004;48(2): 433-444.

  6. GaliSivaranjani, Sirsi Sharad. 3d printing: the future technology in prosthodontics. J Dental and Oro-facial Res. 2015; 11(1):37-40.

  7. Dawood A, Marti Marti B, Sauret-Jackson V, Darwood A. 3D printing in dentistry. Br Dent J. 2015;219(11):521-529.

  8. Prasad KD, Hegde C, Agrawal G, Shetty M. Gingival displacement in prosthodontics: A critical review of existing methods. J Interdiscip Dentistry 2011;1:80-86.

  9. Huang C, Somar M, Li K, Mohadeb JVN. Efficiency of Cordless Versus Cord Techniques of Gingival Retraction: A Systematic Review. J Prosthodont. 2017;26(3):177-185.

  10. Akindoyo JO, Beg MDH, Ghazali S, Islam MR, Jeyaratnam N, Yuvaraj AR. Polyurethane types, synthesis and applications – a review. RSC Adv. 2016;6(115):114453-114482.

  1.  Joseph J, Patel R.M, Wenham A, Smith J.R. Biomedical applications of polyurethane materials and coatings. Trans IMF.2018; 96(3):121-129.

  1. Burke A, Hasirci N. Polyurethanes in biomedical applications. Adv Exp Med Biol. 2004;553:83-101.

  2. OsmanAzlinFazlina, Martin Darren James. Thermoplastic Polyurethane (TPU) / Organo- fluoromicaNanocomposites for Biomedical Applications: In Vitro Fatigue Properties, IOP Conf. Series: Materials Science and Engineering. 2019;701-709.

  3. Dicesare P, Fox WM, Hill MJ, Krishnan GR, Yang S, Sarkar D. Cell-material interactions on biphasic polyurethane matrix. J Biomed Mater Res A. 2013;101(8):2151-2163.

  4. Pucci A.Smart and Modern Thermoplastic Polymer Materials. Polymers (Basel). 2018;10(11):1211-1213. 

Announcements

Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

COPE guidelines for Reviewers

SCOPUS indexing: 2014, 2019 to 2021


Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


Best Article Award

A study by Dorothy Ebere Adimora et al. entitled \"Remediation for Effects of Domestic Violence on Psychological well-being, Depression and Suicide among Women During COVID-19 Pandemic: A Cross-cultural Study of Nigeria and Spain\" is awarded Best Article of Vol 14 issue 23
A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
A study by Saurabh Suvidha entitled \"A Case of Mucoid Degeneration of Uterine Fibroid with Hydrosalphinx and Ovarian Cyst\" is awarded Best article of Vol 14 issue 21
A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
A study by Shafaque M. et al. entitled \"A Case-Control Study Performed in Karachi on Inflammatory Markers by Ciprofloxacin and CoAmoxicillin in Patients with Chronic Suppurative Otitis Media\" is awarded Best Article of Vol 14 issue 17
A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
A study by Singh R. et al. entitled \"A Prospective Study to Find the Association of Astigmatism in Patients of Vernal Keratoconjunctivitis (VKC) in a Tertiary Health Care Centre in India (Vindhya Region MP)\" is awarded Best Article for Vol 14 issue 15
A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
A Study by Mokhtar M Sh et al. entitled "Prevalence of Hospital Mortality of Critically Ill Elderly Patients" is awarded Best Article for Vol 14 issue 12
A Study by Vidya S. Bhat et al. entitled "Effect of an Indigenous Cleanser on the Microbial Biofilm on Acrylic Denture Base - A Pilot Study" is awarded Best Article for Vol 14 issue 11
A Study by Pandya S. et al. entitled "Acute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents" is awarded Best Article for Vol 14 issue 10
A Study by Muhammad Zaki et al. entitled "Effect of Hemoglobin Level on the Severity of Acute Bronchiolitis in Children: A Case-Control Study" is awarded Best Article for Vol 14 issue 09
A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
A Study by Zahoor Illahi Soomro et al. entitled "Functional Outcomes of Fracture Distal Radius after Fixation with Two Different Plates: A Retrospective Comparative Study" is awarded Best Article for Vol 14 issue 05
A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal

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