International Journal of Current Research and Review
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IJCRR - 13(14), July, 2021

Pages: 21-27

Date of Publication: 20-Jul-2021


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Evaluation of Relation between Extraoral Facial Measurement and Mesiodistal Width of the Anterior Teeth

Author: Jeewan Bachan Dhinsa, Sanjeev Mittal, Urvashi Sukhija, Rishabh Ranjan, Manasvi Jamwal, Manini Monica

Category: Healthcare

Abstract:Introduction: The selection of anterior teeth is essential for establishing a correct proportion for facial rhythm and pleasant looks. In the absence of a pre-extraction record, a various extraoral facial landmark can be used to determine the width of maxillary anterior teeth. Using facial measurements to determine the size of the anterior teeth no suitable universal reliable method is present. Objective: This study was done to find the correlation between various extraoral landmarks and the width of six anterior maxillary teeth. Methods: A total of 100 dentate subjects (64 females, 34 male) were included in this in vivo study. The various extra oral-facial landmarks such as the interpupillary distance (IPD), intercanthal distance (ICD), bizygomatic distance (BZW), internal distance (IAD), philtral width (PW) were measured with a digital vernier calliper. The combined mesiodistal width of six anterior teeth (CW) was recorded with a flexible scale. The collected data were analysed using Statistical Package for Social Sciences (SPSS) version 21, software (IBM Inc, USA). Results: Extra oral-facial measurements and CW were higher in the males as compared to the females. Among all the extraoral facial measurement, only Bizygomatic width show significant correlation with the combined width of maxillary anterior teeth. Conclusion: The regression equation 31.291 + 0.040 × BZW can be applied to determine the width of the anterior teeth.

Keywords: Interpupillary Distance, Intercanthal Distance, Bizygomatic Width, Interalar Distance, Regression Analysis

Full Text:

Introduction

In this competitive world full of economically, professionally and socially sound population that is steadily cutting across the limitations and confinements, an attractive and pleasant look is becoming a sheer necessity. As we all know the human face plays a major role in highlighting human appearance in the forms of identity, personality, social identity and the individuals’ self-confidence. 1

 loss of the natural teeth takes a generalised effect on the individual especially the facial appearance which in result leads to creating a psychological trauma to a person leading to poor self-esteem.2 Denture esthetics is defined as ‘the cosmetic effect produced by a dental prosthesis which affects the desirable beauty attractiveness, character and dignity of the individual’.3 It becomes the goal of a prosthodontist to recreate what the ailing individual has lost with simultaneously maintaining the harmony of the facial appearance and the surrounding dento-labial relations of the anterior maxillary teeth. The selection of appropriate sized artificial anterior teeth requires both scientific knowledge and skill.

In the early work before the 19th-century tooth size was determined by the “temperamental theory”, in which the dentist or practitioner determined the tooth forms based on the patients’ health and appearance. This hypothesis was replaced further on by using a system in which facial form was used to determine the tooth form; it was although later on discredited. “Frush and Fischer” then introduced the Dentogenic Theory in which they used the “sex, personality, age (SPA) factor” for selecting the denture teeth.4 hence the early and late 19th century, methods mostly involved the “Trial and Errors” until the patient and dentist established a satisfaction for a particular size of a tooth.

As dentistry is evolving now a day there a numerous parameter for anterior teeth selection which involves parameters such as pre-extraction records which mainly include the photographs, extracted teeth, radiographs and stone models. In the absence of such records, it becomes a major hassle and hurdle in replacing and designing the aesthetics for a completely edentulous patient. Therefore, in such cases, we use various extra oral-facial landmarks as guides for the determination of the mesiodistal width of artificial maxillary anterior teeth.4

The facial proportion was defined as the comparative relation of facial elements in a profile.5 The size, form, and colour of the teeth must be in harmony with the surrounding oral and facial structures, the width of the teeth is considered by some to be more critical than the length.5 several authors have attempted to identify normal tooth dimensions. When no pre-extraction records are available, selecting the proper anterior teeth size for edentulous patients can be difficult. Several efforts have been made to precisely quantify the selection of the anterior teeth.  The golden proportion has been well known for hundreds, per­haps thousands, of years, but Ricketts has been the first orthodontist to apply it to the composi­tion of facial hard and soft tissues. He also used the term ‘‘golden sectioning.’’ Applying a divider, the di­vine proportion is the length of the longer side in 2 linear measurements, at 1.618, and the short side is 1.6,7

According to Young ‘‘it is apparent that beauty, harmony, naturalness, and individuality are major qualities’’ of esthetics.7 Esthetics is one of the primary considerations for patients seeking prosthetic treatment. The size and form of the maxillary anterior teeth are important not only to dental esthetics but also to facial esthetics. The goal is to restore the maxillary anterior teeth in harmony with the facial appearance. However, there is little scientific data in the dental literature to use as a guide for defining the proper size and shape of anterior teeth or determining normal relationships for them.8                           

We all know that facial surface anthropometry is a term used to describe the measurements for the facial features and the method of recording the positions of these facial features. The various facial measurements are substantially based on the spatial correspondence between the definable points present on the face. There have been a total of 20 landmarks and parameters which are of interest for the various medical and dental professionals. In the current era, there are three methods present to conduct the facial measurements they are– Manual anthropometry, 2D photography and 3D stereo-photogrammetry. The method 3D stereo-photogrammetry uses the various laser scanners and records the images as a 3D virtual object which can be further evaluated and viewed from the various aspects.9 This tool has been proved as an excellent guide hut with only a current drawback the cost of the equipment involved.

2D photography has been found as an alternative way to measure the landmarks as an alternative to manual anthropometry. In this method, the photographs are taken of the subject or individual with their head positioned in orientation with their Frankfurt plane horizontal to the ground. In this 2D method measurements are taken from the photograph instead of from the patient directly, but in this method locating the bony structures under the skin requires palpation.  Whereas the manual anthropometry method makes the records and the measurements using sliding and spreading calliper or by using a flexible measuring tape. This technique is easily accessible and of less cost.

However, the studies have shown a lot of variations in their results and also made it clear that no single variable is accurate enough for clinical application. Extraoral landmarks of an individual have been used as a guide for anterior teeth selection. 10,11 Correlating the anterior teeth size and the extra-oral landmarks can help in achieving an aesthetically pleasing appearance.

In the prosthodontics literature, we mostly come across studies of populations outside of India, along with the apparent lack of information about the reliability of determining the width of the maxillary anterior teeth with the various extra oral-facial landmarks. There are no universally accepted parameters for the selection of the width artificial maxillary anterior teeth for the Indian population. Hence the purpose of this in vivo study was to evaluate the reliability of the various extra oral-facial landmarks such as the interpupillary distance (IPD), inner canthal distance (ICD), bizygomatic width (BZW), inter alar distance (IAD), and the philtral width (PW) with the combined mesiodistal width of the 6 anterior maxillary teeth (CW) for the selection of the width of artificial maxillary anterior teeth in the population.

MATERIALS AND METHODS 

The current descriptive cross-sectional in vivo study was done in the department of prosthodontics crown and bridge, Maharishi Markendeshwar College of Dental Sciences and Research, Mullana, Ambala, Haryana, India. The subjects selected were under and postgraduate students. Approval for the study was obtained from the institutional ethical committee (IEC). Written consent was obtained from the subjects and they were explained in detail about the procedure. A total of 100 dentate subjects (male and females) were selected according to the following inclusion and exclusion criteria.

Inclusion criteria

  • Dentulous subjects having permanent maxillary teeth with good alignment.

  • No history of orthodontic treatment or extraction of anterior teeth.

  • Patients having attained the age of 18, complete facial growth.

  • No gross facial asymmetry.

  • No restoration or caries in anterior teeth.

Exclusion criteria

  • Artificial crowns on upper front teeth.

  • Gingival inflammation or hypertrophy of maxillary anterior teeth.

  • Congenital or surgical facial asymmetry defects.

  • Loss of tooth structure due to caries, restorations

  • History or evidence of any dental irregularities, microdontia or macrodontia and malformed teeth.

  • No abnormal pupillary response and vision inability or defect.

Recording of the combined width of the maxillary anterior (CW)

Subjects were seated upright in a dental chair, having their heads supported, so they can look forward towards the horizon and the head is parallel to the floor.   The maxillary impression was made using the irreversible hydrocolloid (Coltoprint-ncr, Coltene). The impressions were thoroughly washed under water and disinfected by spraying 1% sodium hypochlorite solution and poured with type ? dental (Kalabhai Ultrarock).  The combined mesiodistal width of the 6 anterior maxillary teeth (CW) was measured on the dental cast with the help of a flexible millimetre scale, which was kept on the distal most of one canine to the distal-most part of other canine following the curvature of the arch on a dental model

Recording of the extra oral-facial measurements

  1. Inter pupillary width(IPD)

  2. Inter canthal distance (ICD)

  3. Bizygomatic width (BZW)

  4. Inter Alar distance (IAD)

  5. Philtrum Width (PW)

The landmarks were measured using a digital vernier calliper (Yuri) having the following specifications-

  • Measuring field as model: 150m/6in, 200mm/8in, 300mm/12in

  • Resolution: .01mm/.0005in

  • Accuracy (DIN862): max deviation-0.02mm over 100mm, 0.03mm above*

  • Measuring system: Capactive

  • Display: LCD (11mm)

  • Max. Measuring Speed: 3m/s

  • Power Supply: 1×AG13 or SR44 Battery, 1.5v

The IPD was measured from the centre of one pupil to the centre of the other pupil. A steel metal scale was used to mark and depict the centre of the pupil. The ICD was measured as a distance between the medial angles of the palpebral fissures of the eye.  The BZW was measured between the two most prominent point on the zygomatic bone with the help of a facia face bow. The IAD was measured as the distance between the widest points on the outer surface of the alae of the nose on either side. The PW was recorded between the two most prominent parts at the base of the philtrum.

All the measurements were recorded in millimetres. Each reading of extra oral-facial measurement and CW were made 3 times and the mean was obtained.

The collected data were analysed using Statistical Package for Social Sciences (SPSS) version 21, software (IBM Inc, USA). The data so obtained were compiled, tabulated, evaluated and statistically analysed with Tukey Hsd Post Hoc and the Pearson Correlation test.

RESULTS

The Table 1 depicted the mean and standard deviations for the extra oral-facial measurements (in millimetres) for the total population subjects (N-100). The mean and SD for IPD, ICD, BZW, IAD and PW   were 52.6626 +5.85833, 27.5151+  2.92275, 125.0746 + 12.08289, 34.1742 + 9.54873, 14.1366 + 14.72079 respectively.

 The mean of the facial measurements (IPD, ICD, BZW, IAD and PW) for males (N-64) were found to be higher as compared with the female (N-36). When male and female facial measurements were compared with the Tukey Hsd Post Hoc test, the males reported significantly higher IPD (p = 0.012*), ICD (p = 0.036*), BZW (p = 0.017*) as compared to the female population. Although males reported higher IAD (p = 0.222) and PW (p = 0.635) it failed to reach the level of significance Table 2.   

 The mean and SD of combined mesiodistal width of the 6 maxillary anterior teeth (CW) for the total population, females and males were shown in Table 3.  The males (39.5269) reported significantly higher CW (p = 0.041*) as compared to female (38.7052) population.

 Table 4 showed the regression equation with different facial measurement.  Pearson’s correlation coefficient was calculated to measure the strength of a linear relationship between facial measurements and, it was not found to be significant except for BZW which was found to be significant (p=0.0042*), showing a weak positive (0.208) correlation between the variables.

DISCUSSION

The selection of anterior teeth is done to satisfy the esthetics of an individual seeking rehabilitation or a complete denture fabrication. To select artificial teeth, the dentist or clinician requires scientific knowledge as well as artistic skill. The prosthodontist has to very carefully blend the art and science with the arrangement as well as the selection of the anterior teeth.2  

When a completely edentulous patient seeks treatment for rehabilitation with no pre-extraction record available, it becomes great difficult for the dentist to select the proper anterior teeth for the individual 12 To overcome this problem a systematic approach is needed, several anatomical facial landmarks such as IPD, ICD, BZW, IAD and PW have been suggested and said to aid in the estimation and selection of the width of the maxillary anterior teeth.13

Various instruments can be used for recording facial measurements. Different authors used a vernier calliper, Willis Gauge, Boley Gauge in our present study we had used the digital vernier calliper to record the facial measurements and the Facebook to measure the bizygomatic width as done by Rawat et al.2,4,14

A wide variety of instruments had been used to record the intraoral measurements like a piece of string or dental floss,2 digital3 and non-digital vernier calliper, flexible scale. For the measurements of the CW different researchers measured the distance from the curve present between the distal aspects of the two maxillary canines at the contact points. Whereas the other researchers used the cusp tips of the canines.15 The use of the flexible scale had been used in the study conducted by Gomes et al.16 Measuring the combined width of anterior teeth had also been done by recording the individual value of each tooth.14 The type IV gypsum product used to make the dental casts due to its high strength.17

The mean for the inner canthal width in various populations was compared and reported by similar studies by Gomes et al. Lucas et al. and Ellkhawa et al. While the El-sheikh, and Kassab reported lower ICD widths compared to the present study.5,18-21 In a study conducted by Park et al. recording of the bizygomatic width was done by using the widest dimension of the face.22 In a study conducted by Bonakchandarchain the Inter alar value was found to be 36.37mm similar to our study but greater inter alar width were found in the study by Dharap AS et al. 39.8 mm and smaller values reported by Hoffman et al. (34.28 mm) and Al-El-Sheikh (33.27 mm).23,24, 25 In a study reported by Cesario et al.15 The IPD was found to be 59.16mm greater than our study whereas a study by Mishra et al. reported a similar value of IPD as of our study.26 Variation found in the mean values reported can likely be due to racial variations and difference in measuring technique. 

In our study extra oral-facial measurement, CW was more in male as compared to female.  Higher values in males may be due to various factors such as hereditary, robust built, hormones. These findings were also supported by Tripathi et al. Vajro & Nogueira, Smith. and Cesario & Latta.15,27,28

Higher mean inner canthal widths in male compared to females was also found by Gomes et al.and Wazzan et al.5,12 However, a study done in the Brazilian population by Gomes et al. reported statistically insignificant difference for the mean of the ICD between the males and females.5

In this study the use of regression analyses was carried out among the entire facial dimension only BZW showed a significant correlation with CW. The regression method was also used by Isa et al,29 Tripathi et al. Scandrett et al. and Neda et al. in their studies.1,30,31 The estimated combined width of the anterior teeth was found to be less than one-third of the BZW in a study by Tripathi et al.1 which concluded that the BZW is an important landmark for the selection of the anterior teeth.  In our study the combined width of maxillary anterior teeth may be estimated from the equation CWBZW = 31.291 + 0.040 × BZM).  Therefore the use of the regression formulas in the current study may aid in the selection of the anterior teeth for edentulous individuals, for an inexperienced dentist.

Scandrett et al. evaluated various facial parameters such as the bizygomatic distance, the inter-alar width, the inter-commissural width, the sagittal cranial diameter, the inter-buccal frenulum distance, the philtrum width, and the age as predictors for the width of the maxillary anterior teeth and the maxillary central incisors.30 The investigators concluded that no single predictor is accurate enough to be used 100% for the clinical application. Therefore, more than one variable is needed for the prediction of maxillary anterior teeth width.

Similar to our study Authors Patel et al. and Sinavarat et al. also found no significant correlation between the IAD and the CW.32,33 In the study done by Mishra et al,26 the Pearson’s correlation coeffi­cient for the CW and the IAD was found to be weak, negative (except in Aryans), whereas it was found to be highly significant. Also, a significant correlation of value 0.05 level (two-tailed) was found for the Mongoloids. Ellakwa et al. reported a weak and insignificant correlation between IAD and CW. Latta et al. found a non-significant correlation for the BZW and IAD.19,34

 In our study magnitude of the correlation between facial and tooth variable was small, as if the correlation between the variables reach 1, the use for the biometric ratio can justify the prediction, by which the error will be significantly small.26 The investigators concluded that no single predictor is accurate enough to be used 100% for the clinical application. Therefore, more than one variable is needed for the prediction of maxillary anterior teeth width.

The limitations of this study were that this study was conducted in a smaller population. There is a need for further investigations to be done in a larger population as well as in different races. The use of the digital vernier calliper for measurement presents with an inability of the thinner beaks of the calliper to be inserted into tight teeth contacts, as well it had been seen that many individuals do not cooperate with the placement of the calliper to record the facial landmark. The measurements were recorded on the soft tissue landmarks and intra operator reading variations were found in the same individual due to the inconsistent pressure applied during the recording of the measurement. Such difficulties can lead to errors in the measurements.

Clinical implication:  Extra oral-facial landmarks found to remain stable with time, can be used as initial guides to select the width of the anterior maxillary teeth for better aesthetic results when no pre-extraction records are available. More than one facial measurement can be used as a predictor for the selection of the anterior maxillary teeth. The BZW may serve as a reference for establishing the width of maxillary anterior teeth.

CONCLUSION

Based on the findings of the study, it can be concluded that:

1. The extra oral-facial measurements were higher in the males as compared to the females.

2. The combined width of the anterior maxillary teeth was significantly more in males than in females. 

3. Only bizygomatic width showed a significant correlation with the combined width of anterior teeth. 4. The regression equation 31.291 + 0.040 × BZW can be applied to determine the width of the anterior teeth.

Conflict of interest: nil

Source of funding: self

Authors contribution

 1.Dr. Jeewan Bachan Dhinsa-Data analysis

2.Dr. Sanjeev Mittal  -Investigation

3.Dr. Urvashi Sukhija  -Manuscript preparation

4.Dr. Rishabh Ranjan-Statistical analysis

5.Dr. Manasvi Jamwal     -Evaluation              

6.Dr. Manini Monica  -Editing

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  5. Gomes VL, Gonclaves LC, do Prado CJ, Lopes Junior I. Correlation between facial measurements and mesiodistal width of the anterior teeth. J Esthet Restor Dent. 2006;18:196–205.   

  6. Sellen PN, Jagger DC, Harrison A. Methods used to select artificial anterior teeth for the edentulous patient: a historical overview. Int J Prosthodont. 1999;12:51-58.      

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  10. Dwivedi A, Yadav NS, Mishra SK. Inter–Canthal and Inter Alar Distance as a Predictor of Width of Maxillary Central and Lateral Incisor- An In Vivo Study. Ann Med Health Sci Res. 2017;7:276-279. 

  11. Prabha JL, Jain RA. Realiability of intercommissural width in the determination of the width of maxillary anterior teeth in Indian and Malaysian population, Drug Invent Today. 2018;10:506-510.     

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  14.  Mavroskoufis F, Ritchie GM. Nasal width and incisive papilla as guides for the selection and arrangement of maxillary anterior teeth. J Prosthet Dent. 1981;45:592-597.     

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  33. Sinavarat P, Anunmana C, Hossain S. The relationship of maxillary canines to the facial anatomical landmarks in a group of Thai people. J Adv Prosthodont. 2013;5:369–373.     

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A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
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A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
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A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
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A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
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A Study by Vidya S. Bhat et al. entitled "Effect of an Indigenous Cleanser on the Microbial Biofilm on Acrylic Denture Base - A Pilot Study" is awarded Best Article for Vol 14 issue 11
A Study by Pandya S. et al. entitled "Acute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents" is awarded Best Article for Vol 14 issue 10
A Study by Muhammad Zaki et al. entitled "Effect of Hemoglobin Level on the Severity of Acute Bronchiolitis in Children: A Case-Control Study" is awarded Best Article for Vol 14 issue 09
A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
A Study by Zahoor Illahi Soomro et al. entitled "Functional Outcomes of Fracture Distal Radius after Fixation with Two Different Plates: A Retrospective Comparative Study" is awarded Best Article for Vol 14 issue 05
A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


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