International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 13(11), June, 2021

Pages: 112-116

Date of Publication: 04-Jun-2021

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Antifungal Efficacy of Commonly Used Endodontic Irrigating Solutions on C Albicans \? A Systematic Review

Author: Shruti Sudhakar Khade, Anita Babasaheb Tandale, Karishma Krishnakumar, Sayali Anil Maral

Category: Healthcare

Abstract:Introduction: Microorganisms have a pivotal role in the induction and continuing of pulp and periapical pathosis. Objectives: To evaluate antifungal efficacy of commonly used endodontic irrigating solutions on reducing the CFU count of C Albicans in extracted human permanent teeth. Methods: The research question was formulated using the PICO strategy. A planned literature search was conducted by two personnel independently using MEDLINE, PubMed, EBSCO, Scopus, Google Scholar and manual search using College library. Resources were searched from 1st Sept 2009 to 31st August 2019 to identify appropriate studies. Inclusion and exclusion criteria were implicated to select articles. All cross-references lists were also selected. A systematic data extraction sheet was formulated. Results: A total of 101 articles were identified through the data base.13 articles were selected after thoroughly reading full texts and were assessed for eligibility. After going through these 13 articles, it came to notice that no endodontic irrigant has 100% antifungal properties. In many studies, it is evident that out of different concentrations of Sodium hypochlorite, 5.25% concentrated solution showed the best results. Conclusion: From this systematic review it can be concluded that although the antifungal activity of various endodontic irrigating solutions is checked by various authors, no single irrigant proves to be completely successful in reducing the count of candida.

Keywords: Antifungal, Colony-forming units, Disinfecting agent, Extracted human teeth, Irritants, Microorganisms

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Microorganisms have a pivotal role in the induction and continuing of pulp and periapical pathosis. Among the predominant root canal microbiota, fungi play an important role in the failure of root canal treatment. Kakehashietal1 in a classic study proved that bacteria caused pulpal disease; however, numerous studies have revealed a possible role of fungi and more recently viruses in the incidence of endodontic infections. Literature has mentioned that Enterococcusfaecalis, Actinomyces, and Candida albicans were the most prevalent microorganisms associated with failed endodontic treatment. Their presence has been confirmed in dental plaque, dental caries, dentinal tubules, subgingival flora, and infected root canals. 2The genus Candida albicans (C. Albicans) is the most important and influential one. Sen et al found heavy fungal infections in 4 out of 10 teeth and suggested that Candida be considered a dentinophilic microorganism.3

C. Albicansis a versatile microorganism. It exhibits a variety of virulence factors and degrades dentinal collagen. Candida can grow on the dentinal surfaces in the absence of oral tissue fluids and penetrates the dentinal tubules by its various growth patterns. Despite C. Albicans being an aerobic microorganism, it can survive in the harsh environment of the root canal, which primarily favours the growth of anaerobes is because of these unique qualities. C. Albicans has also been isolated in culture samples taken from mixed endodontic infections.4

Waltimo et al5 showed that Candida species was resistant to calcium hydroxide; however, when combined with sodium hypochlorite or CHX it could provide a wide spectrum antimicrobial action with a long-lasting effect. The resistance of Candida to calcium hydroxide and its ability to penetrate dentinal tubules are possible reasons for its occurrence in cases of apical periodontitis.6 This raised the curiosity of researchers to look for the antifungal potency of endodontic irrigants.

Sodium hypochlorite is one of the most commonly used irrigating solutions and is considered a gold standard. It has good antibacterial effects and tissue dissolving properties. But one of the biggest drawbacks of NaOCl is that it has low surface tension and hence it does not penetrate deep into dentinal tubules. This has led to the development of new irrigants which overcome this drawback. Chlorhexidine (CHX) is a biguanide with a wide antimicrobial spectrum that is effective against Gram-positive and Gram-negative bacteria as well as fungi.7,8

There are some antibiotic-based root canal irrigation solutions in endodontics, as well. Adjunctive methods of disinfection like lasers, PDT are also used vividly. Attempts have been made to check the antifungal properties of irrigating solutions.Butthere is no one particular irrigant aiming at eliminating all micro-organism and resulting in successful endodontic treatment. Hence, the search for an ideal root canal irrigant to achieve the goal of disinfection of the canals from all microorganisms continues. 9,10 This systematic review aims to evaluate the antifungal efficacy of various endodontic irrigants on the basis of reduction of the CFU count of C Albicans on extracted human teeth.


This systematic review was done according to PRISMA guidelines.

Eligibility Criteria

Articles in the English language or those having a summary in English were selected. Studies published from 1st Sept 2009 to 31st August 2019 were chosen. In vitro studies done on Human extracted teeth evaluated by Colony Forming Unit were the main criteria while selecting the study. This systematic review included the articles in which methodology showed the use of endodontic irritants only and not a combination of these irrigants with any other material. Review, abstract, letter to the editor was excluded. In vivo studies were also excluded.

Information source

The internet source used to search papers for this study were: The National Library of Medicine(MEDLINE PubMed) and EBSCO HOST, Google Scholar, Google and manual search using DPU college library resources. All cross-references lists of the selected studies were screened for additional papers that could meet up the eligibility criteria. The databases were searched up to and including September 2019 using the search strategy.

Study selection and strategy

The databases were searched for relevant articles with title, abstract, keywords and their combination as follows:

Antifungal OR Antibacterial AND Candida Albicans OR endodontic fungi AND irrigating solutions OR Endodontic irrigating solutions OR root canal irrigants OR dental irrigants OR Sodium hypochlorite OR Chlorhexidine AND Extracted Human Teeth OR Invitro study AND Colony Focal count OR CFU. The yielded articles were assessed further after securing full-text and eliminating duplicates. The titles and abstracts were thoroughly screened and they were either included or excluded based on the inclusion criteria. Articles wherein the antifungal efficacy of one or more endodontic irrigating solution/s was checked against candida Albicans on extracted human teeth and were evaluated by Colony Forming Unit were chosen.

Data collection process

A standard pilot form in the excel sheet was initially used and then those headings not applicable for the review were removed. A pattern of data extraction was done for an article and this was reviewed by an expert and finalized. This was followed for data extraction of all articles. The  data extracted from the included studies were as follows:

  1. Title- Title of the article.

  2. Author – the name of the author.

  3. Year of publication- the year in which the study was published.

  4. Sample size- the number of extracted human teeth included in the study.

  5. Intervention- names and quantity of irrigating solution used.

  6. Technique – materials and method used.

  7. Results- results of the study.

  8. Conclusion – conclusion made from the study.


Study selection

A total of 101 articles was identified through database searching. After reading titles, 64 articles were excluded as they did not match the inclusion criteria. Further 36 articles were assessed for any duplicate and seven articles were removed. The remaining 29 articles were then screened for abstract. After reading the full text of remaining 13 articles were selected and assessed for eligibility. These 13 articles were included in the study (Figure 1). The variables used to extract data i.e. study size, PICOS, methodology, irrigating solution, sample size, the method of preparation of the tooth, colony-forming unit, control used and others are mentioned.


The major goal of root canal treatment is to prepare the canals free of any pathogenic organism to provide a long-lasting treatment of the tooth. Along with bacteria, fungi are also been found in canals of infected teeth or endodontically failed teeth.9 Very few have been evaluated for their antifungal efficacy. Hence the main aim of this systematic review was to discuss the antifungal activity of all the commonly used endodontic irrigants. Thirteen articles were extracted for this systematic review. Routinely used irrigants like NaOCl, CHX, saline, etc. were commonly used for comparison with other materials in the referred articles. Some herbal products like Morinda Citrofolia (MC), Triphala juice, Aloe vera extract, etc. were also tested for their antifungal effectiveness. Some supplementary techniques like laser, photodynamic therapy(PDT) and light-activated disinfection were also studied for their antifungal effectiveness. The studies that used extracted human teeth for the growth of candida and Colony Forming Unit to assess the reduction in the number of Candida were the only ones chosen for this systematic review.

Sodium hypochlorite is one of the most commonly used irrigant in endodontics because of its cheap cost, ease of availability and majorly its tissue dissolving property. It is available in various concentrations of 0.2%, 0.5%, 2.5%, 3%, 5.25% and 6%. The efficacy of NaOCl also depends on its contact time, temperature and concentration. It has been demonstrated that C. Albicans is very susceptible to its action in 0.5% concentration within 10 s of contact time.2 Mohamadi et al2 in 2015 conducted a study to check the antifungal efficacy of sodium hypochlorite in three different concentrations (0.5%, 2.6%, 6%) with CHX (0.2%, 2%), MTAD, Chlor- Xtra, Hypoclean and Tetraclean. Antifungal activity of 6% NaOCl, Chlor-Xtra and 2% CHX was significantly greater than the rest of the irrigants. MTAD was introduced by Mahmoud Torabinejad and associated in the year 2003. It is a combination of 3% doxycycline, 4.25% citric acid and a surfactant. Mohamadi et al3 in 2010 conducted the first study comparing the effect of 1.3% NaOCl, 2% CHX, MTAD and Tetraclean as a final rinse against C.albicans. Similar to the study mentioned above, NaOCl and CHX had the highest Colony Forming Unit reduction with similar results. Tetraclean was found superior to MTAD. MTAD and Tetracleanboth are Doxycycline based irrigants. But Tetraclean was significantly more effective than MTAD because it has deeper penetrating ability due to low surface tension. There is only one study using Hypoclean and it has very low results compared to Tetraclean.9

Propolis is also new biocompatible material in the market with good antibacterial properties. Awawdeh et al.11 checked its antifungal properties of MTAD, 3% NaOCl and 2% CHX and 30% Propolisin the presence and absence of smear layer. The results showed that Propolis was having 70% efficacy, NaOCl up to 90% while CHXupto95%. So, according to this study CHX was a more efficient antifungal agent than NaOCl, which is contrary to many studies considered in this systematic review. Also, no significant difference was seen in the reduction of colony count due to the presence or absence of smear layer according to this study.

Clonidine hydrochloride (OCT) is a bipyridine derivative. OCT has been suggested as an alternative endodontic irrigant based on its antimicrobial effects and lower cytotoxicity. Tirali et al11 in 2011 evaluated the effectiveness of 5.25% NaOCl, 0.1% OCT and 2% CHX at different time intervals of 30 sec, one minute and five minutes as per the groups. It was noticed that 1 ml of 2% CHX for Five minute showed the highest antifungal activity followed by 5.25% NaOCl. 0.1% OCT showed the least antifungal activity. This proved that the more the exposure time of the irrigant, the more potent was the antifungal action.

Zargar et al.13 conducted a study to evaluate the presence or absence of smear layer on the antifungal effect of irrigants at the time intervals of 5 minutes, 30 minutes and 60 minutes. Teeth were prepared. The smear layer was created in 50% (half)of the samples and its removal was done in half of the samples. They were infected with C.albicans. Irrigation with 2.61 % NaOCl, 0.2% CHX and 1% Povidone-iodine (PI) was done for five, 30 and 60 min. They concluded that removal of smear layer proved to be more effective in removing the fungi and 2.6% NaOCl was most potent followed by 2% CHX compared with1% PI.

There is also a study where photodynamic therapy was used in adjunct to sodium hypochlorite by Bruna Paloma de Oliveria et al.14 In this study disinfection protocol used was as follows1% NaOCl, 5.25% NaOCl, 1% NaOCl+ PDT, 5.25% NaOCl+ PDT, saline + PDT. For PDT, methylene blue (15µg/ml) remained in the root canal for two minutes, followed by irradiation with the diode laser. 5.25% NaOCl+ PDT resulted in the highest number of antifungal efficacies. Same antimicrobial effects were seen with 1% NaOCl and 1% NaOCl + PDT. Saline + PDT did not eliminate all microorganisms. This proves that PDT is an additional method for disinfection of canals followed by irrigation, but independently it cannot be much useful for disinfection. The above results coincided with a study conducted by Eldeniz et al.15 They evaluated the antifungal efficacy of light-activated disinfection (LAD/ PDT) in comparison with 2.5% NaOCl and 2% CHX and a new wound antiseptic, OCT. The result showed that the PDT group showed the least antifungal effect. 2.5% NaOCl showed the most antifungal effect followed by 2% CHX and OCT having a similar effect.

Another adjunct for disinfection is lasers. Emelonay et al.16conducted a study to check the antifungal effect of Er, Cr: YSGG laser irradiation at different energy settings to eliminate C. Albicans, with or without 5.25% NaOCl. The specimens were divided into six treatment groupsofNaOCl1-W laser; 1-W laser, NaOCl 0.75-W laser, 0.75-W laser, NaOCl only and a group with no treatment. Although all the groups showed more or less reduction in the Colony Forming Unit count, there was no group showing complete eradication. Lasers when used alone were less effective. But when used in adjunct with NaOClshowed most antifungal action.

Some authors use herbal preparation to check their effect on C.albicans. Choudhary et al.17 check the antifungal properties of Morinda Citrofolia(MCJ) and Triphala juice as endodontic irrigants. Out of the two, MCJ showed higher antifungal efficacy. The disadvantage of these two herbal products was they cause discolouration of teeth. A study by Valera M et al.10evaluated the antifungal properties of Aloe vera, Castor oil and Glycolic Ginger extract and compared them with 2.5% NaOCl and 2% CHX. Although Aloe vera has medicinal value and used as an antimicrobial and anti-inflammatory agent it was not able to reduce all the microorganisms. Despite the antimicrobial effects of Ginger, it didn’t show an effective antifungal effect in the present study. The reason for poor results is attributed to lower concentrations used in the study. Castor oil has a literature background supporting its antimicrobial properties, biocompatibility etc. Castor oil is capable of removing debris similar to 1% NaOCl. This study completely removed the C Albicans.

Juneja et al17 combined 1.3% NaOCl and MTAD and checked its antifungal efficacy comparing with 2.5% NaOCl, 2%CHX and Iodine potassium iodide(IKI). After comparing the above irrigants, it was found that there was a significant reduction in growth but there was no significant difference in the antifungal effect. Also, the CFU counts in the study showed that the antifungal substantivity of IKI was less. 2.5% naocl, 2%CHX showed the highest antifungal effect followed by 1.3% naocl/MTAD. The substantivity nature of CHX is because it absorbs the acidic proteins of hydroxyapatite and gradually releases them inactive cation form.18 Sedigh-Shams et al.19 compared the antifungal effect of Zatariamultiflora EO with that of NaOCl as an irritant for root canals infected with C Albicans.NaOCl was effective than Z multiflora EO with minimum fungicidal concentration.

The study conducted by Chandra et al3 evaluated the antifungal efficacy of 5.25% NaOCl, 2%CHX and 17% EDTA as one subgroup.They compared the antifungal efficacy by adding Clotrimazole as an antifungal agent in another subgroup after irrigation. In the subgroup where irrigants were used without an antifungal agent, 5.25% NaOCl proved to be more potent than 2% CHX and 17% EDTA. When Clotrimazole was flushed in the canals after the irrigation, no difference was observed between NaOCl and CHX group and was more effective than 17% EDTA.


C. Albicans is proven to be responsible for pulpal and periapaical infection. There have been attempts on the complete elimination of C.Albicans in-vitro. Various researchers have tried various irrigants to check their antifungal activity against C.Albicans. All irrigants were able to reduce the Colony Forming Unit count up to some extent. But no specific irrigant showed potent antifungal efficacy equal to NaOCl and CXH. NaOCl is a gold standard endodontic irrigant and is routinely used by the clinician. CHX also has potential antifungal efficacy. Its use as a final rinse will have potential antifungal results. Smear layer removal may aid in increasing the potency of irrigating solutions. The use of adjunctive techniques such as Lasers, PDT, etc. can lead to effective disinfection of root canals from C.Albicans. Although there are various improved irrigating solutions in the market, the search for an ideal root canal irrigating solution to eliminate all the micro-organism continues.

Conflict of interest: None

Acknowledgement: I would like to thank my Guide Dr Anita B. Tandale for her guidance and help throughout the course. I would also like to thank my colleagues Dr Sayali Maral and Dr. Karishma Krishnakumar for their help and support.

Source of Funding: None.

Authors’ Contribution: All the authors contributed equally


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Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

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A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award

A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award

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Disclaimer: International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal.


International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal


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