International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
Bootstrap Slider

Indexed and Abstracted in: Crossref, CAS Abstracts, Publons, Google Scholar, Open J-Gate, ROAD, Indian Citation Index (ICI), ResearchGATE, Ulrich's Periodicals Directory, WorldCat (World's largest network of library content and services)

Search Articles

Track manuscript

Full Html

IJCRR - 13(10), May, 2021

Pages: 84-88

Date of Publication: 19-May-2021

Print Article   Download XML  Download PDF

Review on Constipation in Adults

Author: Monali P. Walke, Sheetal Sakharkar

Category: Healthcare

Abstract:Constipation is a gastrointestinal tract condition that can lead to abnormal stools, uncomfortable storage and passing with pain and stiffness. Acute constipation may required intestines to close, and that may also require surgery. Constipation occurs due to improper diet, Diseases conditions can causing secondary reason forgot constipation. Prevalence of constipation 16 % in adult worldwide (ranging from 0.7 % to 79 %); Prevalence present in adults 60 to 110 years of age at 33.5 %. Great Britain given opinion which is based on the study conducted on healthy person concluded that three bowel movements per week and three bowel movements per day, 99 % of the population an accurate evaluation of the symptom must provide an aware and guided background of the relevant characteristics. Initial history and physical examination, rectal examination, Endoscopy, Anorectal manometry, Barium enema, Colonic transit study are important tools for the diagnosis of Constipation. Pharmacological treatment Bulk-Forming Agents, Stimulants, osmotic agents, Stool Softeners and Emollients, Traditional Chinese Medicine and last one is surgical treatment is given to client for relieving constipation. Abnormal stools, uncomfortable storage and passing with pain and stiffness occurred in constipation. There are lots of risk factor responsible for getting constipation like diet, disease condition etc. For treatment need to medication and also surgical treatment is also available for treating constipation.

Keywords: Constipation, Cause, Diagnosis of constipation, Pharmacological treatment

Full Text:


Constipation is a condition of the gastrointestinal tract which can lead to abnormal stools, uncomfortable storage passage with the feeling of stiffness and pain. Acute constipation may cause a close of the intestine, and that also need to conduct surgery.1 There is no any till ideal constipation definition. Therefore, the main initial approaches can be considered in history and physical examination. By given selfly –reporting constipation and with the help of the formal parameters, several meanings are defined. Other definitions of chronic constipation have been considering in a scientific way like secondary causes like medication, systemic diseases or may be neurological. It is deemed idiopathic or may primarily cause constipation.2

Pathogenesis is multifactor which can put the effect of genetic predisposition, lack of sufficient fluid intake capacity, decreased mobilization, socioeconomic status,  disruption of the hormonal balance, side effects of medicinal products. Constipation is a chronic basically issue of the gastrointestinal tract that causes several community expenditures with an approximate incidence of 1% to 80%, where the disease is distinguished by broad regional variability. It may be led to a broad prevalence of constipation rates.3-5


Constipation is not a disorder, just a symptom. Constipation is more generally regarded as infrequent bowel movements, typically less than 3 stools a week. Nevertheless, individuals may have other grievances, including:

  • Straining of intestinal movements

  • Excessive time required for a bowel movement to pass

  •  Rough stools

  • Pressure with intestinal movements secondary to strain

  • Pain in the abdomen

  • Bloating abdominally.

  • The feeling of an incomplete evacuation of the intestines.


In studies, constipation is described differently, most of the questionnaire-based research study will result from the organic condition. 16% of adult constipation (ranging from 0.7% to 79%) worldwide prevalence of constipation. Prevalence was attributed to 33.5 per cent in adults aged 60 to 110 years).5 This state is heterogeneous, associated with client quality of life and health care facility use. Iran has a constipation rate of 1.4 per cent to 37 per cent. Age refers to the high prevalence of chronic constipation.6-8


Great Britain's opinion on health individuals reported that 99 % of the population had three bowel movements in a week and three bowel movements in a day.7 52% of constipation was described as straining revealed by Sandler and Dross man to move through faecal material. In the survey conducted on young adults who do not seek medical attention, the phase of going through hard stools was felt by 44 %, it was only the uncommon movement of stools felt by 32 %, and 34 % were unable to pass.


The following are factors that may increase your risk of chronic constipation:

  • Be an older adult

  • Being a woman

  • Dehydrated being

  • Eating a diet deficient in fibre

  • Getting little or no physical activity

  • Taking certain medications, including sedatives, opioid pain medications, some antidepressants

  • Take certain drugs, including sedatives, opioid pain medications, certain antidepressants, or blood pressure control medications

  • Having a mental health condition including anxiety or an eating disorder8


Constipation most often happens when waste or stool passes too slowly or can not be easily removed from the rectum via the digestive tract, which can cause the stool to become harsh and dry. Many potential causes of chronic constipation.10


A low-fibre diet, low fluid intake, or dieting can cause or worsen constipation. Dietary fibre helps minimise colonic transport time, raises the bulk of stool but softens stool at the same time. Diets low in fibre, therefore, can contribute to primary constipation.9


Many drugs have side effects of constipation. Some include opioids, diuretics, antidepressants, antihistamines, antispasmodics, anticonvulsants, tricyclic antidepressants, antiarrhythmics, beta-adrenoceptor antagonists, antidiarrheals, ondansetron-like 5-HT3 receptor antagonists, and aluminium antacids.

Medical conditions

Metabolic and endocrine disorders that may lead to constipation include hypercalcemia, hypothyroidism, hyperparathyroidism, porphyria, chronic kidney disease, pan-hypopituitarism, diabetes mellitus and cystic fibrosis. Constipation is normal in people with muscle and myotonic dystrophy, too.


A recurrent cause of constipation is the voluntary withholding of the stool. The choice of withholding may be attributed to reasons such as pain fear, public bathroom fear, or laziness. A mixture of reinforcement, water, fibre, and laxatives can be effective in solving the issue when a child keeps in the stool.


A variety of birth-related illnesses may cause constipation in children. As a group, they are rare, the most common being Hirschsprung's disease (HD). Congenital structural defects can also lead to constipation, including anterior anus displacement, anus imperforation, strictures, and small left colon syndrome.10

Blockages in the colon or rectum

  • Blockages may delay or interrupt the passage of the stool in the colon or rectum. Includes causes:

  •  Narrow skin tears around the anus (anal fissure)

  • A blockage (bowel obstruction) in the intestines

  •  Colon carcinoma11

Problems with the nerves around the colon and rectum

  • The nerves that cause muscles in the colon and rectum to contract and pass stool through the gut may be affected by neurological disorders. Includes causes:

  • Damage to body working nerves (autonomic neuropathy);

  • Multiple Sclerosis

  • Parkinson's illness12

Difficulty with the muscles involved in the elimination

  • Pelvic muscle problems that require bowel movement can cause chronic constipation. Such issues can involve:

  • Impossibility of relaxing pelvic muscles to facilitate bowel movement (anism)

  • Pelvic muscles, which do not adequately manage relaxation and contraction (dyssynergia).13

Conditions that affect hormones in the body

In your body, hormones help regulate fluids. Constipation can result from diseases and conditions that upset the hormone balance, including:

  • Parathyroid gland overactive (hyperparathyroidism);

  • Breastfeeding

  • Underactive (hypothyroidism) thyroid14


Although the frequency of bowel movements is mostly concentrated on in the definition of constipation, consumers can have a wide variety of concerns. The frequently cited lower limit of appropriate stool frequency is three per week and two or fewer stools per week can be used as one of the Rome criteria. The frequency was only one out of six in this summary (including straining, hard stools, and a feeling of incomplete evacuation). Symptoms have been described as straining (decreasingly significant), painfully hard stools, unproductive urges, infrequency and a feeling of incomplete evacuation in patient records.15


The main symptoms of constipation are:

  • Difficulty passing stool

  • Straining when passing stool

  • Passing less stool than usual

  • Lumpy, dry, or hard stool

  • Passage of liquid faecal seepage

  • Infrequent passage of stool

  • Frequent but non productive desire to defecate

  • Straining at stools

  • Nausea and vomiting

  • Anorexia

  • Abdominal distention

  • Dull headache

  • Pain with defecation

  • A loss of appetite16


Variables may be identified for clinical evaluation like stool frequency, consistency, symptom intensity, prolonged obstruction and history of avoiding a defecation call, and feeling of insufficient evacuation. To determine common constipation signs (alarming signs), medical history and environmental causes and also medicines.17,18

Endoscopy: Procedures such as flexible sigmoidoscopy (FS) or colonoscopy are useful by using chronic laxative and mucous lesions to obtain evidence of the cause of unexplained symptoms.17

Anorectal manometry: It is a diagnostic tool for evaluating the activity of anurectomal strain, which can also show rectal compliance with rectal reflexes, rectal sensation etc.

Balloon expulsion testing: It is used for the measurement of dssynergic defecation in addition to anorectal manometry. In addition, BET was administered as part of pelvic floor dyssynergy identification or to separate patients with constipation without pelvic dyssynergy.18

Barium enema: It is a colon X-ray technique for evaluating improvements or structural defects of the colon filled with contrast like metallic material (barium).

Colonic transit study: For recording, a client may need to swallow a capsule with either a radiopaque marker or a wireless device. The movement of the capsule through the colon will be documented on X-rays for several days.19


1. Faecal incontinence: Overflow through moving through isolated obstructing bolus may cause fresh faecal matter to complicate the diagnosis of chronic constipation unless a rectal examination has been performed.

2. Haemorrhoids:  In the anorectal junction plexus and anterior venous anastomoses, excessive stress and intra-abdominal pressure raise venous pressure.

3. Anal fissure: During the evacuation of hard stool, trauma and sudden tearing of the anal mucosa is an indicator of the situation, but the internal anal sphincter spasm is assumed to be the perpetuating cause that triggers the relative ischemia.20


Chronic constipation medications can be classified as bulk forming agents, stool softeners and emollients, osmotic agents, stimulants, chloride channel activators.

Bulk-Forming Agents:  This agent is used in fibre supplements. With the water, these agents can be extended to increase the bulk of the stool and also to increase bowel movements. E.g. Ex. Psyllium (ispaghula husks), polycarbophil of calcium, methylcellulose.

Stool Softeners and Emollients: Usually used stool softener such as Sodium docusate that has a deterrent effect. There is no other known research that compares its independent efficacy with placebo; one double-blind randomised trial showed docusate in chronic constipation was lower than psyllium.

Osmotic Agents: Because of its hyperosmolar existence, agents such as polyethene glycol (PEG), lactulose, sorbitol, and magnesium hydroxide often absorb and retain water and promote stool movement. The stools increase in softness and thickness.

Stimulants: Stimulants work on the colon's myenteric plexus and boost peristaltic contractions. They also elevate water absorption from the lumens. Ex. Senna, Bisacodyl

Chloride Channel Activators: These are essentially the bicyclic fatty acids that can help activate chloride from 2 channels to increase the secretion of intestinal fluid in the apical gastrointestinal epithelium membrane.20,21

Other Treatments:   Lactobacillus and Bifid bacteria should be considered to be associated with harmful pathogens that are bound to the enterocyte surface and then protect the mucosa as symbiotic flora present in the large intestine. These probiotic bacteria are used for the treatment of chronic constipation and other inflammatory bowel diseases. A retrospective study has confirmed that bifid bacterium supplementation can be used for the treatment of dietary hypo-caloric constipation.


If surgical treatment has failed in constipated patients and the use of colon through mechanical emptying can also be administered to clients with slow bowel movements using an enema system as an alternative to treating patients. Colectomy with ileorectal anastomosis can be used in patients with refractory sluggish transit constipation as a treatment option.21


  •  Encourage the client to take 2000 to 3000 mL/Day of fluid, if not medically contraindicated.

  • Enable the client to eat at least 20 g of dietary fibre a day (e.g. raw fruits, fresh vegetables, whole grains)

  • Regular exercise and activity


  • Constipation related to pain on defecation 

  • Constipation related inactivity

  • Constipation related decreased dietary  intake


Constipation is a condition of the gastrointestinal tract which can lead to abnormal stools, uncomfortable storage passage with the feeling of stiffness and pain. Acute constipation may cause the closure of the intestines, and that also need to conduct surgery. 24. 2% is the prevalence of functional constipation.  Age is associated with a High prevalence of chronic constipation. There are many risk factors are can be discussed which can cause constipation like  Age and gender distribution, medication, diet, Disorders. Diagnostic evaluation, complication and its management included in this review.


In the general population, the prevalence is 16%  (Range between 0.7 % and 79 %).  Clearly understanding the pathophysiology of chronic constipation and information regarding the pharmacological agent's efficacy and safety can help physicians treat and manage constipation symptoms. The efficacy of various treatment methods has been given. Substantial frustration in patients does not have to be avoided. It comes to mind that who required for identifying the components in their terms. Complete history, full physical,  digital rectal evaluation and detailed evaluation. Lubiprostone and linaclotide can be considered as two beneficial medications if the effects are not minimized by the laxatives. It is worth noting that biofeedback therapy is a valuable tool to boost symptoms of bowel and dyssynergic defecation. When medical care of constipated patients has failed, surgical procedures can be implemented.

Acknowledgement: Authors acknowledge the immense help received from Principal Dr. Seema Sing, Dept. Of MSN,SRMMCON. Sawangi (M), Wardha, Author also thankful Ms. Ranjana Sharma HOD of dept. of MSN, Sawangi (Meghe), Author also Thankful Guide Ms. Sheetal Sakharkar, Clinical Instructor, Dept. Of MSN, Sawangi (Meghe), for her guidance. The author acknowledges the immense help received from the scholars whose articles are cited and included in references of this manuscript. The authors are also grateful to authors/editors/publishers of all those articles, journals and books from where the literature for this article has been reviewed and discussed."

Conflict of interest: None

Financial support: Self


1.         Bronner F. Nutritional Aspects and Clinical Management of Chronic Disorders and Diseases. CRC Press; 2002.Vol 1.352

2.         Camilleri M, Thompson WG, Fleshman JW, Pemberton JH. Clinical management of intractable constipation. Ann Intern Med 1994;121(7):520–528.

3.         FORCE T. Guidelines for the diagnosis and therapy of the vein and lymphatic disorders. Int Angiol 2005;21(2):68-107.

4.         Abbott RD, Petrovitch H, White LR, Masaki KH, Tanner CM, Curb JD, et al. Frequency of bowel movements and the future risk of Parkinson’s disease. Neurology 2001;57(3):456–462.

5.         Schnabel L, Buscail C, Sabate J-M, Bouchoucha M, Kesse-Guyot E, Allès B, et al. Association between ultra-processed food consumption and functional gastrointestinal disorders: Results from the French NutriNet-Santé cohort. Am J Gastroenterol 2018;113(8):1217–1228.

6.         Cutler DM, Ghosh K, Messer KL, Raghunathan TE, Stewart ST, Rosen AB. Explaining the slowdown in medical spending growth among the elderly, 1999–2012. Health Aff (Millwood) 2019;38(2):222–229.

7.         Walter S, Hallböök O, Gotthard R, Bergmark M, Sjödahl R. A population-based study on bowel habits in a Swedish community: prevalence of faecal incontinence and constipation. Scand J Gastroenterol 2002;37(8):911–916.

8.         Pearce J, Hunter JO. Nutrition and the Gastrointestinal Tract for Athletes. Sport Exerc Nutr. 2011;264–280.

9.         Gant SG. Diseases of the Rectum, Anus, and Colon: Including the Ileocolic Angle, Appendix, Colon, Sigmoid Flexure, Rectum, Anus, Buttocks, and Sacrococcygeal Region, C by Samuel Goodwin Gant With 1128 Illustrations on 1085 Figures and 10 Insets in Colors  Saunders Company; 1923.

10. de Lorijn F, Reitsma JB, Voskuijl WP, Aronson DC, Fiebo J, Smets AM, et al. Diagnosis of Hirschsprung’s disease: a prospective, comparative accuracy study of common tests. J Pediatr 2005;146(6):787–792.

11.       Rees PM, Fowler CJ, Maas CP. Sexual function in men and women with neurological disorders. Lancet 2007;369(9560):512–525.

12.       Catto-Smith AG. 5. Constipation and toileting issues in children. Med J Aust 2005;182(5):242–246.

13.       Albain KS, Barlow WE, Shak S. Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with nodepositive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a andomised trial. Lancet Oncol 2010;11:55–65.

14.       Gordon JS. The Effectiveness of Reflexology as a Adjunct to Standard Treatment in Childhood Idiopathic Constipation A Single Blind Randomised Controlled Trial [PhD Thesis]. Edinburgh Napier University; 2007.

15.       Whorton JC. Inner hygiene: constipation and the pursuit of health in modern society. Oxford University Press, USA; 2000.

16.       Avila-Rencoret FB. A Novel Endoscopic Scanning-Probe Device for Rapid Screening of Gastrointestinal Dysplasia [PhD Thesis]. Imperial College London; 2014.

17.       Lam TJ. Clinical approach to anorectal disorders. 2015; Thesis. Research VU University Amsterdam, graduation VU University Amsterdam. unknown (

18.       Kathpalia H, Sharma K, Doshi G. Recent trends in Hard Gelatin capsule delivery System. J Adv Pharm Educ Res 2014;4(2).

19.       Andrews GR. Diarrhoea and constipation in geriatric practice. Cambridge University Press; 1999:152–158.

20.       Bao HF, Liu L, Self J, Duke BJ, Ueno R, Eaton DC. A synthetic prostone activates apical chloride channels in A6 epithelial cells. Am J Physiol-Gastrointest Liver Physiol. 2008;7(3):172-6.

21.       Wallis M, McKenzie S, Gyett S, Rayner K, Ellem F, Gass E, et al. Help patients win the constipation battle: Best practice in the prevention and treatment of constipation in adults under 65 years. J Adv Pharm Educ Res 2003;4(5):23-6.


Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

COPE guidelines for Reviewers

SCOPUS indexing: 2014, 2019 to 2021

Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to for more details.

Best Article Award

A study by Dorothy Ebere Adimora et al. entitled \"Remediation for Effects of Domestic Violence on Psychological well-being, Depression and Suicide among Women During COVID-19 Pandemic: A Cross-cultural Study of Nigeria and Spain\" is awarded Best Article of Vol 14 issue 23
A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
A study by Saurabh Suvidha entitled \"A Case of Mucoid Degeneration of Uterine Fibroid with Hydrosalphinx and Ovarian Cyst\" is awarded Best article of Vol 14 issue 21
A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
A study by Shafaque M. et al. entitled \"A Case-Control Study Performed in Karachi on Inflammatory Markers by Ciprofloxacin and CoAmoxicillin in Patients with Chronic Suppurative Otitis Media\" is awarded Best Article of Vol 14 issue 17
A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
A study by Singh R. et al. entitled \"A Prospective Study to Find the Association of Astigmatism in Patients of Vernal Keratoconjunctivitis (VKC) in a Tertiary Health Care Centre in India (Vindhya Region MP)\" is awarded Best Article for Vol 14 issue 15
A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
A Study by Mokhtar M Sh et al. entitled "Prevalence of Hospital Mortality of Critically Ill Elderly Patients" is awarded Best Article for Vol 14 issue 12
A Study by Vidya S. Bhat et al. entitled "Effect of an Indigenous Cleanser on the Microbial Biofilm on Acrylic Denture Base - A Pilot Study" is awarded Best Article for Vol 14 issue 11
A Study by Pandya S. et al. entitled "Acute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents" is awarded Best Article for Vol 14 issue 10
A Study by Muhammad Zaki et al. entitled "Effect of Hemoglobin Level on the Severity of Acute Bronchiolitis in Children: A Case-Control Study" is awarded Best Article for Vol 14 issue 09
A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
A Study by Zahoor Illahi Soomro et al. entitled "Functional Outcomes of Fracture Distal Radius after Fixation with Two Different Plates: A Retrospective Comparative Study" is awarded Best Article for Vol 14 issue 05
A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award

A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award

RSS feed

Indexed and Abstracted in

Antiplagiarism Policy: IJCRR strongly condemn and discourage practice of plagiarism. All received manuscripts have to pass through "Plagiarism Detection Software" test before Toto Macau forwarding for peer review. We consider "Plagiarism is a crime"

IJCRR Code of Conduct: To achieve a high standard of publication, we adopt Good Publishing Practices (updated in 2022) which are inspired by guidelines provided by Committee on Publication Ethics (COPE), Open Access Scholarly Publishers Association (OASPA) and International Committee of Medical Journal Editors (ICMJE)

Disclaimer: International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal.


International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal


148, IMSR Building, Ayurvedic Layout,
        Near NIT Complex, Sakkardara,
        Nagpur-24, Maharashtra State, India

Copyright © 2023 IJCRR. Specialized online journals by ubijournal .Website by Ubitech solutions