International Journal of Current Research and Review
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IJCRR - 13(5), March, 2021

Pages: 26-31

Date of Publication: 03-Mar-2021


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Evaluation of Covid-19 Awareness and Understanding Amongst Pharmacy Students at Gayatri College of Pharmacy Sambalpur, Odisha

Author: Ray B, Biswal PK, Panda BB, Dash SN

Category: Healthcare

Abstract:Introduction: Global Pandemic COVID-19 caused by Severe acute respiratory syndrome Coronavirus 2(SARS COV 2) spreading rapidly and become a serious challenge for the entire healthcare profession. It results in a significant burden on the human race. There is no effective treatment so far discovered for the SARS CO V 2. As the modified strain of the virus is new the research on various aspect like pathogenesis, prognosis, etc are limited due to lack of time and rapidly spreading. The best measure is prevention by maintaining social distancing and other hygienic measures. Objective: The surveyor study Aims to determine the level of awareness, perception and professional knowledge of COVID 19, Global pandemic in different aspects like mode of transmission, Preventive and Precaution and approved treatment protocol among Pharmacy students at various stages in the study. one of the vital aims is to identify the key source of gained awareness as well as identify which of these were is the most effective in information delivery. Methods: A cross-sectional study was conducted among Pharmacy students of Gayatri Colege of Pharmacy, Sambalpur using a questionnaire total of 50 Participants who fully completed the questionnaire were included in the Study. Results: Participants were surveyed on their knowledge including the source of Information, Possible source of creating awareness. Conclusion: The result suggests that Participants basic knowledge about COVID-19 is acceptable. Although improvements are advised in the understanding of preventive measures that can be taken, Recommended more focus towards it as it is so helpful in creating Awareness.

Keywords: Pandemic, COVID-19, Pathogenesis, Awareness, Social Distancing, Sanitisation, Vaccine

Full Text:

Introduction

The World Health Organization (WHO) “defines coronavirus as a large family of viruses that cause illness ranging from the common cold to more severe disease”. The name comes from the Latin word “corona”, which means “crown” or “halo”, and refers to the shape of the virus particle when viewed under a microscope. “Coronaviruses are zoonotic, meaning they are transmitted between animals and people”, the WHO says. Coronavirus is an infectious disease caused by a type of common virus that infects humans, typically leading to an upper respiratory infection (URI). Seven different types of human coronavirus have been identified. Most people will be infected with at least one virus in their lifetime.1,2

Corona virus disease 2019(COVOD-19) caused by this newly discovered virus has very quickly spread all over the world. Considering the rapidly increasing number of cases the WHO declared a pandemic on 11th March 2020. The incubation period of this disease transmitted by droplets ranges from 2 to 14 days, usually between 3 and 7.3,4 On Jan. 7, 2020, The virus has been isolated in china by the Chinese authority of Health. The virus pathogenesis was quite a new model. To understand the Pathology of Infection at that time was quite crucial.

SARS-CoV-2 is a single-stranded, positive-sense RNA coronavirus which causes an illness called COVID-19 (note that many people still equate and interchange the disease name COVID-19 with the new official virus named SARS-CoV-2). It is a new strain of coronavirus which is causing an Illness of Respiratory tract. Sometimes it is mild, sometimes moderate, sometimes serious. People who have other underline problem or comorbidity factor, they are high risk.

Pathogenesis

The severe symptoms of COVID-19 are associated with an increasing number and rate of fatalities especially in the epidemic region of China. On January 22, 2020, the China National HealthCommissionreportedthe details of the first 17 deaths and on January 25, 2020, the death cases increased to 56 deaths. The percentage of death among the reported 2684 cases of COVID-19 was approximately 2.84% as of Jan25, 2020 and the median age of the deaths was 75(range 48–89) years. Patients infected with COVID-19 showed higher leukocyte numbers, abnormal respiratory findings, and increased levels of plasma pro-inflammatory cytokines. One of the COVID-19 case reports showed patient at 5 days of fever presented with a cough, coarse breathing sounds of both lungs, and a body temperature of 39.0 °C. The patient's sputum showed positive real-time polymerase chain reaction results that confirmed COVID-19 infection. The laboratory studies showed leucopenia with leukocyte counts of 2.91 × 10^9 cells/L of which70.0% were neutrophils. Additionally, a value of 16.16 mg/L of blood C-reactive protein was noted which is above the normal range(0–10 mg/L). High erythrocyte sedimentation rate and D-dimer were also observed. The main pathogenesis of COVID-19 infection as a respiratory system targeting virus was severe pneumonia, anaemia, combined with the incidence of ground-glass opacities, and acute cardiac injury. Significantly high blood levels of cytokines and the-machines were noted in patients with COVID-19 infection that includedIL1-β, IL1RA, IL7, IL8, IL9, IL10, basic FGF2, GCSF, GMCSF, IFNγ, IP10, MCP1, MIP1α, MIP1β, PDGFB, TNFα, and VEGFA. Some of the severe cases were admitted to tertiary care hospital or hospital specially design for Corona Patient.5 The infection is manifested by the following abnormality in laboratory test result: Leucopenia, lymphocytopenia, Increase level of LDL and CRP. The imaging technique is an important tool for the diagnosis. Chest computed tomography is presently recommended by an expert as a screening examination.6,7

Mode of Transmission

As it is a kind of Respiratory Infection, the main mode is Droplet Infection. Droplet of respiratory material when move in air, nearby person gets infected. Surface contact is another main mode of infection as the virus sustained for the long term in any surface. Transmission can be occurred by respiratory droplet or surface contact of the infected spot as the virus exists for a long time in the surface inactive form. person to person infection occurs which is known as community spread.8

Sign and Symptom

Signs and symptoms of COVID-19 infection include flu-like symptoms that worsen to

    • fever,

    • coughing, and

    • shortness of breath.

    • Headache and body ache

    • sometimes Diarrohea.

Sometimes flu-like symptom starts and sometimes runny nose which may resemble another flu symptom. Difficulty in breathing is the outcome of Untreated Infection. Early diagnosis is essential. It is early in the outbreak of this new disease, so the current approximation of the mortality rate may go up or down.9

Treatment and Prevention

Globally many drug and therapies are being considered or used for treatment. Usually, the drug treatment is approved by concern healthcare administration of that region. But sometimes Doctor is using a treatment that has not been approved for COVID-19. They are treating the patient using drug beyond their indication, approved use and with few scientific evidence. Sometimes they are advancing drug by extrapolation from in-vitro studies indicating their antiviral and anti-inflammatory study.10 China where the pandemic was originated, Hospitals are using traditional Chinese medicine which has been reported to be good effect.11,12

As severe acute respiratory syndrome SARS CO V-2, the causative agent of COVID-19 has a close genetic resemblance with the SARS-CO V and the middle east respiratory syndrome. (MERS) CO V, drugs used to treat SARS and MERS are utilised to explore the extent of their activity against SARS CO V 2.Due to the rapid spread of the disease and its high rate of contagion as well as the cost and time for development and marketing of a new, safe and efficacious drug, professional and researcher are looking to repurpose new drug to treat COVID-19.13

The virus is new. So the research on various aspects like pathogenesis, treatment, the prognosis is limited to due lack of time versus rapid spread of virus globally. There is no specific therapy approved by the US Food and Drug Administration (FDA). For the present virus, only symptomatic treatment and treatment by antibiotics and antiviral drug trial basis following previous knowledge and individual complication. It will take time for the discovery of the vaccine and an appropriate drug for target-specific treatment. But the protocol of treatment given currently is highly successful in maximum cases. So the recovery rate is also quite satisfactory. The most important method to control the disease is to take preventive measure like social distancing, washing of hands frequently and using a face mask at public places, etc. Government of different countries are making strict rules for their citizens by implementing lockdown followed by shut down which doesn’t affect much because now the people should learn the art of living along with the virus. The main objective is to make social distancing between individuals which is the ray of hope in present scenarios.14

MATERIALS AND METHODS

A lot of Studies has attempted to explore knowledge and attitudes of healthcare professionals of various disciplines like Nursing, pharmacy and Medicine professional Students. The Subject area are TB,AIDS,Diabetes,Hypertension etc.But in the present area COVID-19, This type of survey is few in number or very rare in Pharmacy decline.

A study carried out by Akin, et al (2011) investigated the level of knowledge and attitude towards understanding and creating awareness of Turkish Nursing Students about the disease TB, intending to determine whether making changes to their teaching and this type of survey would improve their attitude, as a result of the reflection of awareness in Society.15 Singal, N(1999) Also perform a Survey in the field of Communicable disease TB among Nurses working in a Tuberculosis Hospital.16 This type of Survey Design is quite helpful for students and Healthcare worker to understand the Disease-related information in an interesting way. Later on, the knowledge will be propagated and transmitted in society for creating a high magnitude of Awareness through professionals. The present survey has been designed by following the framework/model of the above study.

Study Question

The present study sought to explore the degree of COVID-19 Awareness among Pharmacy Student at GCP and identify the key point of gained awareness.

This was a questionnaire-based cross-sectional study. The participant's information and were questionnaire distributed in Web Base class to Pharmacy student at GCP by the researcher. The questionnaire was made up of twenty multiple type question divided into three separate categories. Section A contains Demographic information meant to understand the difference in Awareness and level of knowledge between different population group. Section B contains five-question relating to COVID 19 Awareness and Possible source of existing knowledge. The rest of the question was mentioned in Section C which included detail question on cause, transmission, symptom and medication etc, aims to test Participants basic understanding of COVID-19. The final question in this section explored participants attitude to creat Awareness as a student of the Healthcare profession. All participants were provided with information as the short discussion about COVOD -19 to support their learning after they send their response.

Sampling methods

Participants were exclusively Pharmacy Students at different stages of study at the GCP with the understanding that their comp questionnaire lesion of the questionnaire will imply their consent to participate in this study. Few incomplete questionnaires were later on omitted from data set which resulted in yielding a total of 50 complete response.

Data Analysis

Statistical analysis has been carried out by using SPSS Software and excel programme. Before running analysis responses were screened for the incomplete response(i.e Partially answered or completely unanswered questionnaire .) which were subsequently removed from data set. The questionnaire with more than three unanswered questions is considered as incomplete. The analysis consisted using frequency distribution for the total participant sample and each demographic characteristics. Dichotomous formatting enabled detail analysis of responses within each participant.

Results

Demographic characteristic of Respondents

The analysis involved 14 pharmacy students (64% female and 36 % male) from two selective semesters in Study. The age range of participant was 18-24. Sources of gained awareness and education were also explored to identify which method was most effective in their opinion.

Covid Awareness and Source of Existing  Knowledge

All respondent indicated that they have Previously heard about COVID-19. Among participant twenty-five per cent, student indicate that

Participants basic understanding of COVID-19

Majority of participants identify and indicate the appropriate method of creating awareness. Maximum Participant identified COVID-19 is a Viral Disease. Most Participants agreed that COVID-19 is a viral disease. Most participants indicated that Anganwadi (the local group for primary health screening programme under Govt of Odisha and India), Participate in Primary screening of health for COVID-19. Most of the participant agreed that Maintaining Social Distancing, Repeatedly sanitisation of hand, Using face mask, Avoiding to touch any external object is a series or package for prevention of COVID-19 in community. [Ethical clearance-Ethical requirement for the survey was granted by principal Gayatri college of pharmacy who is also one of the co-authors for the Manuscript. No-GCP/000

Participant COVID awareness and self-identified source of knowledge

Following data (Table 1) indicates the awareness and general knowledge about sources of COVID 19 Information

 

Understanding Transmission and Possible Treatment of COVID-19

Table 4 indicated the Distribution of correct answer provided by participants regarding transmission and possible treatment of COVID-19.

Discussion

Participants were surveyed on their knowledge including the source of Information, Possible source of creating awareness. Participants have also surveyed on their knowledge the causative organism and basic idea about COVID-19 which include the mode of spread, treatment management and possible method of Prevention to spread within the community.

The finding has highlighted the need to increase awareness and a boosting tool for enhancement of current education, knowledge and awareness about COVID-19, Among Pharmacy students, who are highly professional as a community pharmacist in Creating Social awareness in Community. Most participants were third and Fifth-semester students. Male participants were considerable ow when compared to female participants.

Conclusion

Participants basic knowledge about COVID-19   is acceptable. Although improvements are advised in the understanding of preventive measures that can be taken, Recommended more focus towards it as it is so helpful in creating Awareness.

Acknowledgement:

The authors are highly thankful to the Student Society of GCP. The authors also highly acknowledge the help of the Staff member of Dept of Pharmacology GCP for encouraging the students to participate in the Survey.

Conflict of Interest and Source of Funding

There is NO Conflict of interest with the article.

There is NO EXTERNAL FUNDING SOURCE.

CONTRIBUTION OFF AUTHORs :

1. Dr. B. Ray: Designing of Manuscript and Analysis of Data

2. Dr. P.K. Biswal: Collection of Data

3. Dr. B.B. Panda: Tabulation of data

4. Prof. S.N. Das: Deals with the ethical matter.

References:

[1] World  Health  Organization. Clinical management of severe acute respiratory infection when novel coronavirus  (nCoV)  infection is suspected  https://www.who.int/publicationsdetail/clinical-management-of-severe-acute-respiratory-infection-when-novel-coronavirus(ncov)-infection-is-suspected.

[2]  CDC Website:  https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-guidancemanagement-patients.html.

[3] Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak

associated with a new coronavirus of probable bat origin. Nature 2020;579:270-273.

[4] Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome

coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): the epidemic

and the challenges. Int J Antimicrob Agents 2020;55(3):105924.

[5]  Chu  CM,  Cheng  VCC,  Hung  IFN,  Role of lopinavir/ritonavir in the treatment of  SARS: initial virological and clinical findings.  Thorax  2004;59(3):252-256. 

[6] Jin YH, Cai L, Cheng ZS, Cheng H, Deng T, Fan YP, et al. A rapid advice guideline for

the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected

pneumonia (standard version). Mil Med Res 2020 Feb 6;7(1):4.

[7] Bernheim A, Mei X, Huang M, Yang Y, Fayad ZA, Zhang N, et al. Chest CT findings

in coronavirus disease-19 (COVID-19): relationship to duration of infection.

Radiology 2020;295(3):200463.

[8] Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He XJ, et al. Clinical characteristics of

coronavirus disease in 2019 in China. N Engl J Med 2020; 382(18):1708-1720.

[9] Jin  Y, Cai  L, Cheng  Z. A rapid advice guideline for the diagnosis and treatment of 2019  novel coronavirus (2019-nCoV) infected pneumonia (standard version). Military Med Res 2020;7:4.

[10] Kalil AC. Treating COVID-19-Off-label drug use, compassionate use, and randomized clinical trials during pandemics. JAMA 2020;323:1897-1898.

[11] Ji S, Bai Q, Wu X, Zhang DW, Wang S, Shen JL, et al. Unique synergistic antiviral effects of shifting jiedu capsule and oseltamivir in influenza A viral-induced acute exacerbation of the chronic obstructive pulmonary disease. Biomed Pharmacother 2020;121:109652.

[12] Yao KT, Liu MY, Li X, Huang JH, Cai HB. Retrospective clinical analysis on treatment of novel coronavirus-infected pneumonia with traditional Chinese medicine Lianhua-Qingwen. Chin J Exp Tradit Med Form 2020;12:1-7.

[13] Folegatti PM, Ewer KJ, Aley PK, Angus B, Becker S, Belij-Rammerstorfer S, et al. Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: A preliminary report of a phase 1/2, single-blind, randomised controlled trial. Lancet 2020;396:467-478.

[14] Ray B, Motalebi M, Nanda SS. Global Pandemic COVID 19: The art of living with the virus. J Hospital Pharm 2020;15(3):67-74.

[15] Gorak AS, Unsure G, Molaglu S, Godzilla M, Durna ZK. Knowledge of and attitudes towards tuberculosis of Turkish Nursing and Midwife students. Nurse Education Today 2011;31(8):774-779.

[16] Singal N, Sharms P, Jain R. Awareness about tuberculosis among Nurses working in a tuberculosis hospital and a General Hospital in Delhi, India. Int J Tuberc Lung Dis 1999;2(12):1005-1010.

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One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

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This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

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A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal

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