International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 13(2), January, 2021

Pages: 67-70

Date of Publication: 16-Jan-2021


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A Comparative Clinical Evaluation of Access Cavity Preparation Using Dental Operating Microscope and Conventional Preparation for Conservation of Tooth Structure

Author: Manoj Chandak, Pradnya Nikhade, P. Sindhu, Anuja Ikhar, Rakhi Chandak, Abhilasha Dass, Nidhi Motwani

Category: Healthcare

Abstract:Background: The outcome of endodontic therapy is associated with eradication of micro-organisms from the root canal system and avoidance of re-infection. Optical magnifications have extended the horizons of dental treatment. Recently, illumination and magnification have established to help provide precise anatomic details. The canal orifices can effortlessly be identified under a microscope than with surgical loupes or the naked eye. Objective: The comparison of the conservation of tooth structure during access cavity preparation under the microscope with the conventional method. Methods: Thirty patients were selected for whom root canal treatment where indicated. The patients were divided into two groups Group 1 \? Access cavity prepared conventionally and Group 2 \? Access cavity preparation under the microscope. The measurement between intercanal orifice was done using Vernier callipers. Results: In the present study, there was a reduction in measurement between mesiobuccal to the distal orifice and mesiobuccal to mesiolingual orifice but it was not statistically significant. There was a reduction in measurement from mesiolingual to distal orifice. The reduction was statistically significant (p=0.018) Less amount of tooth structure is removed therefore allowing for conservation of tooth structure resulting in improved strength tooth strength, which is clinically important. Conclusion: The conservative endodontic cavity (CEC) preparation to reduce the loss of tooth and preservation some of the roofs of the pulp chamber and peri-cervical dentin was reported in the literature.

Keywords: Conservative endodontic cavity, Pre-operative radiograph, Distal canal orifice

Full Text:

INTRODUCTION

The mandibular first molar poses many anatomic challenges and most frequently endodontically treated tooth, but it also. The access cavity has an external outline form evolving from internal pulpal anatomy of the tooth. First mandibular molar generally has 2 roots and 3 root canals. However, due to genetic, ethnic and gender varieties, a wider range of anatomical, as well as morphological deviations, can be encountered. The difficulty lies in the location of the number and position of orifices on pulp chamber floors.1 This is particularly correct when the tooth is excessively restored, calcified or malpositioned. The commonly used method to evaluate the morphology of root canal involves staining of the root canal and tooth clearing, plastic injection, conventional and digital radiography and radiopaque gel infusion and radiography.2 The clinician should be clear and thorough about root canal morphology of tooth being treated since it can affect the treatment outcome3 The outcome of endodontic therapy is associated with eradication of micro-organisms from root canal system and avoidance of re-infection.4 Optical magnifications have extended the horizons of dental treatment. Recently, illumination and magnification have established to help provide precise anatomic details. The canal orifices can effortlessly be identified under a microscope than with surgical loupes or the naked eye.5 Based on lens system microscope can be classified into the simple or compound microscope. The lens system varies from double to 2 plano-convex. Based on magnification, the microscope can work under low, mid-range and high magnification. The microscope has higher magnification in the range of X2.5 to X30 with better illumination using fibre optic technology. The reflecting microscope wherein an opaque substance requires light that reflects from the object to the lenses in an optic tube.6 One of the uses of magnification in endodontics is the conservation of access opening.7 So the purpose of the present study was the comparison of the conservation of tooth structure during access cavity preparation under the microscope with the conventional method. The research question was does magnification using Dental operating microscope aid in the conservation of tooth during access cavity preparation in endodontic treatment as compared to the conventional method.8,9

In the present study, we aimed to assess the conservation of tooth structure using the conventional method in root canal treatment. Further, we assessed the conservation of tooth structure using a dental operating microscope in root canal treatment and compared the conservation of tooth structure using the conventional technique with dental operating microscope in root canal treatment.

MATERIALS & METHODS

The study was performed at Department of Conservative Dentistry and Endodontics Sharad Pawar Dental College & Hospital, Sawangi, Wardha after getting approved by ethical committee (IEC reference no. DMIMS(DU)/IEC/Dec-2019/8616).

Selection of data

Thirty patients were selected for whom root canal treatment where indicated. Patients were explained about the procedure in detail and informed consents were obtained. Mandibular 1st molars were selected for the study.

Inclusion Criteria

  • Teeth with caries involving enamel, dentin and pulp requiring root canal treatment.

  • Teeth with completely developed roots.

Exclusion criteria  

  • Teeth with evident periapical pathology, tooth mobility, root resorption.

  • Patients with medical conditions,

  • Pregnant, lactating women.

Informed written consents were obtained from each patient before treatment.

Procedure

Radographs

A pre-operative radiograph (IOPA) was taken from different angulation to study the dimensions of the pulp chamber, number of canals and length of the root. This helps in the correct approach of access cavity preparation. 10

Access opening

Patch test was performed to check for allergy for a local anaesthetic solution. After proper palpation of anatomical landmarks, Local anaesthetic was administered into the retromolar area to block the Inferior Alveolar nerve. Mandibular first molar was isolated with a rubber dam. The patients were divided into two groups ( Table 1)

For Group 1

Conventional cavity preparation was done using #4 carbide or round diamond no 4 or #557 tapered fissure bur was used. The bur was advanced through the central fossa until a drop was felt. The drop indicates that the pulp chamber is explored. Safely ended bur was used to restrict the depth to avoid cutting of floor of the tooth. All canals orifices were located with DG16 explorer and enlarged with G.G drill. Measurement – Measurement between intercanal orifice was done using Vernier callipers and listed in the table.

For Group 2

Standardized access cavity preparation was done under an operating microscope with 12 X magnification. The measurement between intercanal orifice was done using Vernier callipers and listed in the table

Statistical Analysis

The data was collected and analyzed using by comparing the mean and by Wilcoxon sign-rank test.

RESULTS

The strength of the tooth is directly proportional to the amount of removal of dentin. More the removal of dentin more will be the tooth structure loss and this causes weakening of the tooth. The destruction was evaluated by measuring the distance between the orifices using Vernier callipers.

 

Graph represent mean of distance between mesiobuccal to distal canal orifice(mbd): mesiolingual to distal canal orifice (mld) and mesiobuccal and mesiolungual canal orifice (mbml)  in access cavity prepared under microscope and conventional preparation

DISCUSSION

The scientific-technical advance in endodontics in the last years has been increasing the incidence of success of the treatment of root canals. The absence of spontaneous and provoked painful symptomatology, hermetic sealing, and dental element rehabilitated in masticatory function, and the healing of the apical and periapical tissue are clinical criteria of success in endodontic therapy.11 An endodontically treated teeth, one of the failures is the fracture of the tooth. The conservative access cavity preparation was anticipated to diminish fracture possibility of endodontically treated teeth.12 Since the 2000s in clinical practice, dental operating microscopes have been utilized as the best reliable aid. The microscopes aid in recognizing then dentinal coverage present over the orifice. Further, this dentinal coverage could be removed accurately with an ultrasonic instrument which would help in recognization of canal orifice.5 Further the microscope also helps to analyze the dentinal wall for the carious lesion.13 As stated by Dr. Carr “You cannot treat what you cannot see”. The conservative endodontic cavity (CEC) preparation to reduce the loss of tooth and preservation some of the roofs of the pulp chamber and peri-cervical dentin was reported in the literature. 14 Therefore, the removal of dentin was evaluated by measuring the distance between the orifices using vernier callipers.

In the present study, there was a reduction in measurement between mesiobuccal to the distal orifice and mesiobuccal to mesiolingual orifice but it was not statistically significant. There was a reduction in measurement from mesiolingual to distal orifice. The reduction was statistically significant (p=0.018) Less amount of tooth structure is removed therefore allowing for conservation of tooth structure resulting in improved strength tooth strength, which is clinically important.15 Paul Krasner and Henry Rankow in 2004 stated that microscope enhances the capability of the location of the canal orifices/ number on pulpal floor. If there is the presence of anatomical landmarks, then the task of locating orifices will be more systematic and, consequently, with superior certainty. The law of change in colour aids in location canal orifice. However, the difference in colour between the floor and walls of the pulp chamber is stressful to differentiate with the unaided eye. Also, the walls of the pulp cavity were constantly concentric to the external surface of the tooth at the level of the CEJ, Also at the level of the CEJ, the distance from the external surface of the tooth to the wall of the pulpal chamber was equal all through the circumference.16 Magnification with illumination provided with the microscope is helpful to prevent the stress on the human eye. The microscope helps in the determination of the dentinal map that is of key importance in locating the canal. Carr et al reported that using the DOM clinically, their ability to identify MB2 canals in maxillary 1st  molars increased by 20%.17 According to Carr et al, the frequency of detection of the MB2 canal was 17% without magnification and was increased to 63% using loupes and 71% using the DOM. According to Enrique Merino, the microscope increases the ability of the dentist to locate and negotiate the hidden canal.18 The use of the microscope increases the predictability of the treatment. Ultimately this increases the success rate of the endodontic treatment. Mittal et al concluded that the number of orifices detected increased with  increasing  magnification.18

CONCLUSION

The art of dentistry is based on precision. The unaided eye can only see up to canal orifice, Microscope function as 3rd eye for Endodontist. This study showed that access cavity prepared under dental operating microscope conserved more tooth structure as compared to the conventional technique. A statistically significant difference was noted with mesio lingual orifice to distal orifice in conventional access cavity preparation as compared to the dental operating microscope when the inter-orifice distance was measured. We can recommend that the access cavity preparation should be performed under magnification with the help of a dental operating microscope to retain the strength of dentin and prevent tooth fracture that will help in the long period success of the procedure.

Acknowledgement- Authors acknowledge the immense help received from the scholars whose articles are cited and included in references to this manuscript. The authors are also grateful to authors/editors/publishers of all those articles, journals and books from where the literature for this article has been reviewed and discussed.

Conflict of Interest- Nil

Source of Funding- Nil

References:

  1. Karunakaran JV, Samuel LS, Rishal Y, Joseph MD, Suresh KR, Varghese ST. Root canal configuration of human permanent mandibular first molars of an Indo-Dravidian population-based in Southern India: An in vitro study. J Pharm Alli Sci 2017 Nov;9(1): S68.

  2. khlaghi NM, Khalilak Z, Vatanpour M, Mohammadi S, Pirmoradi S, Fazlyab M, Safavi K. Root canal anatomy and morphology of mandibular first molars in a selected Iranian population: an in vitro study. Iranian Endod J 2017;12(1):87.

  3. Nixdorf DR, Moana-Filho EJ, Law AS, McGuire LA, Hodges JS, John MT.  Frequency of persistent tooth pain after root canal therapy: a systematic review and meta-analysis. J Endod 2010 Feb; 36(2):224-230.

  4. Fabra-Campos H. Three canals in the mesial root of mandibular first permanent molars: a clinical study. Int Endod J 1989 Jan; 22(1):39-43.

  5. Gogiya RJ, Chandak MG, Modi RR, Bhutda P, Kela S, Chandak RM. Magnification in dentistry: A review. Int J Appl Dent Sci 2018;4(2):89-93.

  6. Pecora G, Andreana S. Use of the dental operating microscope in endodontic surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1993;75:751-758.

  7. Low JF, Dom TN, Baharin SA. Magnification in endodontics: A review of its application and acceptance among dental practitioners. Eur J Dentistry 2018 Oct;12(04):610-616.

  8.  Reeh ES, Messer HH,  Douglas WH. Reduction in tooth stiffness as a result of endodontic and restorative procedures. J Endod 1989;15(11):512-516. 

  9. Ayse DK, Bulem UK, Erhan S. Determination of canal ori?ce co-ordinates and MB2 incidence of maxillary ?rst molars in a Turkish subpopulation. Odontologica Scandinavica. 2014; 72: 354-361.

  10. Corsentino G, Pedullà E, Castelli L, Liguori M, Spicciarelli V, Martignoni M, Grandini S. Influence of Access Cavity Preparation and Remaining Tooth Substance on Fracture Strength of Endodontically Treated Teeth. J Endodontics 2018;3(6):543-547.

  11.  Osman IA, Ahmed H. The Effect of Access Cavity Design on Fracture Resistance of Endodontically Treated First Molars: In Vitro Study. Dove Press 2017; 5(9):443-451.

  12. Özyürek T, Ülker Ö, Demiryürek EÖ, Yilmaz F. The Effects of Endodontic Access Cavity Preparation Design on the Fracture Strength of Endodontically Treated Teeth: Traditional Versus Conservative Preparation. J Endod 2018;44(5):800-805. 

  13. Rathi NV, Chandak MG, Mude GA. Comparative Evaluation of Dentinal Caries in Restored Cavity Prepared By Galvanic and Sintered Burs. Contemp Clin Denst 2018;9(1):S23-27.

  14. Saygili G, Uysal B, Omar B. Evaluation of the relationship between endodontic access cavity types and secondary mesiobuccal canal detection. BMC Oral Health 2018;18:121.

  15. Mukherjee P, Patel A, Chandak M, Kashikar R. Minimally Invasive Endodontics a Promising Future Concept: A Review Article. Int J Sci Study 2017;5(1):245-251.

  16. Krasner P. Rankow HJ. Anatomy of Pulp Chamber Floor. J Endod 2004;30(1): 5-16.

  17. Carr G.B, Murgel C. The use of the operating microscope in Endodontics. J Dental Clin 2010; 54(2;191-214.

  18. Endodontic Microsurgery, Ouintessence Company Ltd 2009.

Announcements

Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

COPE guidelines for Reviewers

SCOPUS indexing: 2014, 2019 to 2021


Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


Best Article Award

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A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
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A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
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A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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Disclaimer: International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal.



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International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal

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