International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 4(18), September, 2012

Pages: 171-175

Date of Publication: 29-Sep-2012


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GASTROSCHSIS ASSOCIATED WITH OTHER ANOMALIES - A CASE REPORT

Author: Arun Kumar.S.Bilodi, M.R.Gangadhar

Category: Healthcare

Abstract:Aim of the study :-The objective of present study is to report a case of gastrochisis associated with multiple congenital anomalies that is born to consanguineous mother Place of study : in the labor ward at Teaching Hospital of Raja Rajeswari Medical College,Bangalore, Period of Study:-During three years period of study (2008\-2010) Case Study :-A male child was born to consanguoious mother in the labour ward of above institution with presence of coils of small intestines outside the body wall associated with jejunal atresia ,imperforate anus and club foot. The Scoliosis of spine (deformity of spine).was also present and other systems were normal. No other anomalies were found in this new born male baby. Discussion: Since this is a case of Multiple Congenital Anomaly (MCA), this case has been well compared,,correlated and discussed with the available literature of other cases showing multiple congenital anomalies showing gastrointestinal Anomalies like gastrochisis , amphalocele,atresia of any part of gastrintestinal tract,imperforate anus etc. Conclusion:This is case of Gastroschisis associated with Multiple Congenital Anomalies (MCA) has not only profound embryological importance but also give profound knowledge of gastroscisis with multiple congenital anomalies of gastrointestinal tract to the Anatomists, Surgeons and Physicians . Hence this case has been studied well and reported

Keywords: Gastroschsis, -- Abdominal wall defect .Paraomphalocele -Abdominoschisis—Laproschisis

Full Text:

INTRODUCTION
Gastroschsis is defect in the abdominal wall in the developing fetus during pregnancy by the formation of a hole in the abdominal wall through which allows intestine and other organs come out. These are not covered by any protective sac but exposed to amniotic fluid. Intestines may be shortened,twisted,swollen or may become irritated .Child may require surgery immediately after birth by pushing back the intestinal coils into the abdominal cavity Even after surgery child may have problem of feeding, digestion and absorption of food.”.According to the .Center for disease control and prevention(CDC), around 1871 babies are born with gastrochisis every year in USA1 . It has been stated by some authors that Gastroschsis occurs to the right of umbilicus and may be associated with Artesia of intestines (10%) .(Cincinnati children’s Hospital Medical center.). Maternal History This anomalous child was born normally to consanguoious mother after term in the middle class family..This was third child to her and other two children (one male and a female child )were normal but they were born by caesarean sections There was history of hydramnios during this pregnancy and family history of consanguinity, but there was no history of taking drugs or infection during first trimester. No history of smoking and alcohol intake. No systemic diseases in the family. METHODOLOGY A live male child was born to consanguoious mother aged 23 years in the labor ward at Teaching Hospital of Raja Rajeswari Medical College,Bangalore.. Once the child was born, cried well , minimum muconium was present on the body .Baby was cleaned well and weighed. The weight of the .new born male child was 3.0.kg..There was no difficulty in respiration. All the systems were examined in detail and they were found to be normal except Gastro intestinal system and anterior abdominal wall.. On general exaination Head and neck – Normal,, Face – normal, Chest – normal Extremities :-Upper limbs were normal There were ten digits. with no anomalies of digits . Spine : Scoliosis of spine (deformity of spine).was present Lower limbs:-Normal but there was club foot(deformity of foot) of the right foot .left lower limb was normal with normal ten digits No polydactyly or syndactyly of both upper and lower limbs were found in this new born child. Local examination of the abdomen On the detailed examination, child had defect in the anterior abdominal wall. with coils of intestine lying outside the abdominal wall These were coils of small intestine were not covered by any protective membrane or sac There was part of stomach herniating The opening of aperture was quite large measuring approximately 5.5 cms . There was also associated anomalies like jujenal atresia ,imperforate anus. Scrotum was normal .Testes were present in the srcotum.No other congenital inguinal or umbilical hernias were found. No anomaly of bladder or other pelvic organs..No other anomalies observed in this new born baby other than above anomalies. After examination was complete, photograph of anterior abdominal was taken.

DISCUSSION
The incidence of Gastroschsis in United States is 1 in 5000 infants. Cases of Gastroschsis are increasing world wide and in United States of America. This congenital disorder also has affected in infants having background of ethnic. These anomalies can be diagnosed by ultra sound also but exact etiology is not known in the fetus About 5 cms vertical opening is present in the abdominal wall adjacent to the umbilical cord Rarely large intestine along with other organs may be herniated through the opening New borns with gastrochisis are either have a low birth weight or prematurely born. They have associated anomalies like bowels which are underdeveloped or part of genetic syndrome or disorder Pregnant mothers have shown increase level of alpha feto protein in their blood due to presence of gastrochisis of fetus Mothers using recreational drugs in early period of pregnancy or smoke during pregnancy are highly prone for getting infants with Gastroschsis. 2 . Mothers of younger age are likely to have babies with Gastroschsis and mothers of white teenagers have higher incidence of Gastroschsis infants than in Black or African –American teenagers3 Babies with Gastroschsis are found more in mothers who consume more of alcohol and use tobacco in the form of smoking4 Use of certain drugs like Ibuprofen during pregnancy carries high risk of delivering babies with gastrochisis and also in women who have repeated urinary tract infections before pregnancy or early part of pregnancy have high risk of delivering babies with Gastroschsis5 Yuvaraj Bhosale et al (2007) have reported a case of multiple congenital anomalies having Omphalocele,extrophy of cloaca with imperforate anus and,Spinal defects(OEISComplex) in a still birth full time fetus to non consanguineous mother of 21 years old.There was no history of drug intake nor infection in her first trimester. Antenatal ultra sonography revealed omphalocele associated with polyhydramnios, congenital dislocation of hip on both sides with calcaneo vulgus feet deformity ,imperforate anus,genital ridge was unfused and there was splitting of genital tubercle .Hence sex could not made out . There was also kyphosis of lumbar spine.6 In India Incidence of multiple congenital anomalies(MCA) is 1.94% - 2.03% as per the analysis of all published studies 7and8 According to I.C.Verma (1978), the commonly occurring multiple congenital anomalies are defects of neural tubes with anomalies of cardio vascular systems, or musculo-skeletal system ,and gastro intestinal systems9The causative factors of major multiple congenital anomaly is due to genetic factors (30%-40%)environmental factors (5%-10%).Among anomalies caused by genetic, chromosomal abnormality constitutes only 6% , disorders of single gene constitutes 25% and multifactorial constitutes 20-30% and cause of 50% of multiple congenital anomalies is idiopathic 10. A study was conducted by Saarah Waller et al from 1987 to 2006 on all cases of live born infants with gastroscisis.They established a link between infants with gastroscisis and agricultural chemicals like atrazine ,nitrates,and 2,4dichlorophenoxyacetic acid .They found occurrences of gastroscisis was high due to contamination of water with atrazine Incidence of gastroscisis risk was also increased in a women who concieved in the spring that is between month of March,April and May due to more use of chemicals.during these months11 . This is case of multiple congenital anomalies seen in full term new born male baby involving gastro intestinal system(showing gastroscisis, jejunal atresia imperforate anus,),skeletal system club foot(deformity of foot) and scoliosis of spine, (deformity of spine) and polyhydramnios, but there was no congenital dislocation of hip on both sides nor omphalocele as seen in studies of Yuvaraj Bhosale et al (2007) studies No incidences of neural tube defects, nor anomalies of cardiovascular systems unlike in studies of I.C.Verma (1978), PRESENT STUDY In present case, a full term male baby was born normally to 23 years old mother of Bangalore in labor ward at Teaching Hospital of Raja Rajeshwari Medical College, Bangalore, Karnataka with coils of intestine lying outside the Anterior Abdominal wall. These coils of small intestine were not covered by any membrane or sac. On close examination, there was part of stomach also herniating along with coils of intestine on close examination The opening of aperture was quite large(approximately 5.5cms wide),In this case, environamental factor has not played any role unlike in studies conducted by Sarah Waller et al On examination of abdomen Coils of intestine were moist with adequate blood supply,and there was atresia of jejunum. Stomach was just protruding. There were no other organs seen at opening of the anterior abdominal wall.There was associated anomaly of club foot(deformity of foot) and scoliosis of spine (deformity of spine). No anomaly of bladder and other pelvic organs It is second degree consanguinity, hydramnios, and past family history of anomalies which may be the contributing factors for the occurrence of the present anomaly of Gastroschsis. The immediate surgery was done on this child by placing all the coils of intestine and stomach back into cavity of the abdomen and opening was closed in layers .Post operative period was uneventful Later child was shifted to Neonatal ICU.

CONCLUSION
It is the ultra sound that has played a prominent role in the diagnosis of anomalies in gestation period (antenatal period).Early diagnosis is of paramount importance to obstetrician to plan for further management. Anomalies found after birth also can be to treated either immediately after birth or after certain specified time This case of multiple congenital anomalies with gastroscisis as main anomaly gives knowledge of anomalies not only to Anatomists but to surgeons of all clinical branches and physicians This study of anomaly is of paramount importance to community medicine in bringing down the incidences of morbidity and mortality of anomaly ,through Health workers ,social workers and volunteers ,and NGOs. ANOMALY committee or caell can be set to bring down incidences of Anomalies in coming years . Hence this case has been studied and reported.

ACKNOWLEDGEMENT
Sincere thanks to:-1)Medical Director,.2)Medical Superintendent and 3)Prof and HOD OF Obstretrics and Gynaecology of Teaching Hospital of Raja Rajeswari Medical college Bangalore for permitting me to examine the cases. The immense help received from the scholars whose articles are cited and included in the references of this manuscript .The authors are also grateful to authors/editors/publishers of all these articles ,journals,books,from where the literature for this article has been reviewed and discussed .

References:

1. Parker.S.E, Mai CT,Canfield MA,Richard.R,Wang Y,Mayer RE, et al :for the National Birth Defects Prevention Network .Updated national birth prevalence estimates for the selected birth in the United States .2004-2006.Bith Defects Res A Clin Mol Teratol .2010 Sept 28 (EPub ahead of print)

2. Yang Ping ,Terri.H Beaty,Muin.J,Khoury,Elsbeth Chee, Walter Stewart and Leon Gordis ‘’Genetic Epidemiologic study of omphalocele and gastrochisis evidence in heterogeneity” American journal Medical genetics 44(2005)668-675;

3. Williams LJ, Kucik JE, Alverson CJ, Olney RS, Correa,A,: Epideomology of Gastroschsis in Metropolitan Atlanta 1968 through 2000 Birth Res A 2005;73:177-83,

4. BirdsTM, Robbins JM, Druschel C, Cleves MA,Yang S, Hobbs C A.and National Birth Defects Prevention study(2009) Demographic and environmental risk factors for gastrochisis and omphalocele in the National Birth Defects Prevention study: .J.Pediatr Surg ;44:1546-1551.

5. Feldkamp ML, Reefhuis J, Kucik J, Krikov S,Wilson A, Moore CA,Carey JC,Botto.LD,and National Birth Defects Prevention study,Case –control study of self reported genitourinary infections and risk of gastrochisis : findings from the National Birth Defects Prevention study-1997 - 2003,BMJ,2008,Jun 21;336(7658);1420-3.

6. YuvaRaj Bhosale,Laxmi Rajgopal, Nandanwar,YS;:Omphalocale,Exstrophy of cloaca ,imperforate anus,and Spinal Defects,(OEIS Complex);A case Report and Review of literature;J.Anat Soc.56.(1) :2007:41—43.

7. MadhavanT and Narayan.J.(1991)- Consanguinity and mental retardation – Journal of Mental Deficiency Research 1991:35:133-139 

8. Verma I.C,Prema A,Puri.A.K(1992):-Health effects of Consanguinity in Pondicherry ,Indian pediatrics 1992,,29,685-692

9. Verma I.C,(1978);-High frequency of neural tube defects in North India –Lancet -1978-1- 879-880.

10. Sayee Rajangam ,Rama Devi(2007):- Consanguinity and chromosomal abnormality in mental Retardation or multiple congenital abnormality.-Journal of Anatomical Society of India- Vol56(2),DEC-2007 -30-33p.

11. Sarah Waller MD,Kathleen Paul .MD.,Suzanne Peterson .M.D., and Jane Hitti .M.D.,of the university of Washington,Seattle Society for Maternal – Fetal Medicine (2010,February 7).Link between birth defect gastroscisis and the agricultural chemical atrazine found . Science Daily.Retrieved March 12 2011, from http://www.Science daily.com/releases /2010/02//1000205081805.htm.

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Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


Best Article Award

A study by Dorothy Ebere Adimora et al. entitled \"Remediation for Effects of Domestic Violence on Psychological well-being, Depression and Suicide among Women During COVID-19 Pandemic: A Cross-cultural Study of Nigeria and Spain\" is awarded Best Article of Vol 14 issue 23
A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
A study by Saurabh Suvidha entitled \"A Case of Mucoid Degeneration of Uterine Fibroid with Hydrosalphinx and Ovarian Cyst\" is awarded Best article of Vol 14 issue 21
A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
A study by Shafaque M. et al. entitled \"A Case-Control Study Performed in Karachi on Inflammatory Markers by Ciprofloxacin and CoAmoxicillin in Patients with Chronic Suppurative Otitis Media\" is awarded Best Article of Vol 14 issue 17
A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
A study by Singh R. et al. entitled \"A Prospective Study to Find the Association of Astigmatism in Patients of Vernal Keratoconjunctivitis (VKC) in a Tertiary Health Care Centre in India (Vindhya Region MP)\" is awarded Best Article for Vol 14 issue 15
A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
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A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
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A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
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A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal

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