International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 4(21), November, 2012

Pages: 91-94

Date of Publication: 15-Nov-2012


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A STUDY ON MODIFIED ALVARADO SCORING SYSTEM IN DIAGNOSING ACUTE APPENDICITIS

Author: C.P. Ganesh Babu, E.M.J. Karthikeyan, K. Bharaniraj Kumar

Category: Healthcare

Abstract:Aim: To study the role of Modified Alvarado scoring system in diagnosing acute appendicitis in clinical practice. Materials and Methods: A prospective study was conducted on 250 patients admitted with abdominal pain suggestive of acute appendicitis and were operated, from January 2008 to December 2009 in AVMC&H and MAPIMS. Both males and females patients from 8 years to 60 years of age were included. Preoperative modified Alvarado score was used in all, and the results were compared with operative finding and biopsy. Results: 155 patients were identified to have score of 8 or more. 149 patients were confirmed by biopsy. 91 patients have score 5 -7 and 66 were confirmed by biopsy. Conclusion: This scoring system is a reliable and diagnostic modality to increase the accuracy in diagnosing appendicitis.

Keywords: Alvarado. Scoring system. Acute appendicitis

Full Text:

INTRODUCTION
Acute appendicitis is one of the most common surgical emergency. Its lifetime prevalence is 1 in 7. its incidence is 1.5 to 1.9 / 1000 in male and female population. Surgery for acute appendicitis is the most frequent operation performed in all emergency. The diagnosis of acute appendicitis is purely based on history, clinical examination and laboratory investigations. Negative appendicectomy rate is 15 to 40% as per literatures. Delay in diagnosis definitely increases the morbidity, mortality and cost of treatment. Early diagnosis is a primary goal to prevent morbidity and mortality.(1) Alvarado in 1986 introduced a criterion for the diagnosis of acute appendicitis which was later modified to accommodate additional parameters along with original Alvarado scoring system.( 2- 5). The aim of the study is to evaluate the sensitivity of modified Alvarado scoring system in the diagnosis of acute appendicitis, to reduce the rate of negative appendicectomy and to reduce the complications of acute appendicitis.

MATERIALS AND METHODS
A total number of 250 cases of clinically suspected acute appendicitis were studied from the period of January 2008 to December 2009 in AVMC&H in pondy and MAPIMS . Data including age , sex, symptoms, physical sighs and laboratory findings such as white blood cells total and differential count were recorded in modified Alvarado form. (Table 1). (6) In addition, urine for routine examination was done for all cases. ultra sonogram of abdomen was performed when diagnosis was doubtful, especially in female patients to exclude gynecological diseases.

The score of each patient was correlated with the clinical, operative and histopathological findings.

RESULTS
Age of the patients ranged from 7 years to 60 years with the majority of the patients in the third decade (46%) followed by second decade (25%). (Table 2). Out of 250 patients, 155(62%) were males and 95 (38%) were female. clinically males were more susceptible than females. (Table 3). All the specimen were sent to laboratory for histopathological examination. The reports showed features of acute appendicitis in 215 (86%) cases and 35 (14%) patients did not have acute appendicitis. (Table 4). In this series, patients with score of 8- 10, 5 – 7, and 1- 4, had 96%, 72.5%, and 0% sensitivity respectively. (Table 5). Patients with score 8 and above, the sensitivity is 98.04% in male and 92.45% in females.(table 6). Patients with score less than 8, the sensitivity is 79.24% in male and 57.15 % in females and overall is 68.72.%. (Table 7).

DISCUSSION
Results of this study shows acute appendicitis was most common in the 21 – 30 years(46%). Next most common group was 11 -20 (26%). All the studies have shown that appendicitis is more common in 10- 30 years of age .(7) Males more susceptible than females .(8) A negative rate of appendicectomy of 20- 40% is not unusual finding in literature (9) . Negative appendicectomy in this study is 15.75%, male (8.4%), females (23.1%). The percentage of normal appendicectomy in varies series varies from 8 to 33%. In this era many surgeons accept 15 to 20% negative appendicectomy (10) . From this study it was found that the higher the score, more of its sensitivity. Patients with the Alvarado score ranges 8 -10, 5 – 7 and 1 – 4 have accuracy of 96%, 72.5% and 0% respectively. Fengo at al reported a sensitivity of 90.2% and others reported a sensitivity of 73% with negative laparotomy rate 17.5% .(11) In this series, the sensitivity of the patients with the score 8 and above was 98,04% in males and 92.45% in females and combined sensitivity is 95.45% whereas the sensitivity with score less than 7 was 79.24% in males, 57.15% in females and combined sensitivity is 68.75%. This study also reveals that scoring system was more helpful in male patients by showing high accuracy rate as compared to female patients. Lower values in female patients were due to presence of diseases in genital system (i.e.) ovaries, salpinges (4, 12) . In females, additional investigations are required. Different literatures also support these observations (13). However there are no signs , symptoms or laboratory test that are 100% reliable in the diagnosis of acute appendicitis. In this study modified Alvarado scoring system showed that the accuracy of the diagnosis was very dependable and acceptable in higher scores but patients with lower scores should be observed. Patients with score 8 to 10 are almost certain to have appendicitis and they should undergo operation immediately. Patients with a score 5 to 7 indicate probable appendicitis. they should be observed and evaluated every 4 to 6 hrs, if the score remains the same or increases after this, reevaluation is required and patients with the score of 4 or less are very unlikely but not impossible to have appendicitis and they can be discharged from hospital after giving initial conservative treatment.

CONCLUSION
In the diagnosis of acute appendicitis, the modified Alvarado score is a fast, simple, reliable, noninvasive repeatable and safe diagnostic modality without extra expense and complication. It can be very useful for junior doctors provided it is applied purposefully and objectively in patients. The application of this scoring system improves diagnostic accuracy and consequently reduces negative appendicectomy and this reduces complication rates.

References:

1. Wagner JM, McKinney WP, Carpenter JL, Does this patient have appendicitis? JAMA 1996; 276; 1589-94.

2. Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med 1986;15: 557- 564.

3. Owen TD, William H, Stiff G, Jinkinsen LR , Rees BI, Evaluation of Alvarado score in acute appendicitis. J R Soc Med 1992; 85: 87- 8.

4. 0hnmann C, Yang O, Frank C. Diagnostic score for acute appendicitis. Abdomen pain study group. Eur J Surg 1995; 161: 273- 281.

5. Macklin CP, Radcliffe GS, Merei JM, STRINGER md. A prospective evaluation of modified Alvarado score for acute appendicitis in children. Ann R Coll Surg Engl 1997; 79: 203 -205.

6. Al-Fallouji MAR, Postgraduate surgery, the candidates Guide. Oxford: ButterworthHeinemann; 1998: 388- 389.

7. Addiss DG, Shaffer N, Fowler BS, et al. The epidemiology of appendicitis and appendicectomy in united states. Is J Epidemiology 1990: 132: 910 -25.

8. Williams NS, Bulstrode CJK, O’Connell PR, Bailey and love’s short practice of surgery. 25th Ed. London. Hodder Arnold, 2008; 1205- 1206.

9. Al Qahatani HN, Muhammed AA, Alvarado score as an admission criterion for the suspected appendicitis in adults. Saudi J Gastroenterology 2004: 10: 86- 91.

10. Jones PF, suspected acute appendicitis , trend in management over 30 years. B J Surg 2001; 88: 1570 – 1577.

11. Fengo G, Lindberg G, Blind P, Enochsson L, Oberg A. Diagnostic decision in suspected acute appendicitis : validation of simplified scoring system. Eur J Surg 1997: 163; 831 – eight.

12. Baber MD, Mclarn J, Rainay JB. Recurrent appendicitis. Br J Surg 1997: 84: 110 -112.

13. Shrivastona UKJ, Gupta A, Sharma D , Evaluation of the Alvarado score in the diagnosis of acute appendicitis. Trop Gastroenterol 2004; 25:184-6.

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A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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