ENZYMES AND ANTIOXIDANT AS BIOMARKERS IN BREAST CANCER

Pavithra V.; Sathisha T. G.; K Kasthuri; D. Siva Mallika; S. Jeevan Amos

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IJCRR - 6(11), June, 2014

Pages: 24-29

ENZYMES AND ANTIOXIDANT AS BIOMARKERS IN BREAST CANCER

Author: Pavithra V., Sathisha T. G., K Kasthuri, D. Siva Mallika, S. Jeevan Amos

Category: Healthcare

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Abstract:

Objectives: Current study was undertaken to determine the clinical utility of enzyme biomarkers like Alkaline phosphatase and Lactate Dehydrogenase as well as antioxidant like uric acid in diagnosis , prognosis and metastasis. Methods: 50 clinically and histopathologically confirmed female breast cancer patients of the age group of 30-65 years served as cases and 50 normal healthy females in the same age group served as controls. The parameters were estimated by standard biochemical methods. Results: Serum Alkaline Phosphatase and Lactate Dehydrogenase levels are significantly higher in cases than controls. Where as uric acid levels are non significantly increased in cases. Conclusions: Significant increase of serum enzymes Alkaline phosphatase and Lactate Dehydrogenase along with simultaneous non significant increase of uric acid was observed in the study. These biomarkers can be utilized in remote areas where smaller labs operate at low cost and unexposed to sophisticated knowhow.

Keywords: Breast cancer, Alkaline phosphatise, Lactate Dehydrogenase, Uric Acid, Biomarker

Citation:

Pavithra V., Sathisha T. G., K Kasthuri, D. Siva Mallika, S. Jeevan Amos. ENZYMES AND ANTIOXIDANT AS BIOMARKERS IN BREAST CANCER International Journal of Current Research and Review. 6(11), June, 24-29

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List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award

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