International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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Abstract

IJCRR - 6(24), December, 2014

Pages: 31-34

ASSESSMENT OF ARTERIAL STIFFNESS AMONG MIDDLE AGED OFFSPRING OF DIABETIC PARENTS

Author: Niruba R., Subha K. C., Vijayalakshmi I.

Category: Healthcare

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Abstract:

Background: Genetic susceptibility appears to play an important role in the occurrence of Type 2 Diabetes with high prevalence among first degree relatives .Subjects with type 2 diabetes have 2-3 fold increased risk of cardiovascular disease compared with normal population. Aim: To compare the arterial stiffness between normotensive normoglycemic middle aged offspring of diabetic parents (Cases) with normotensive normoglycemic middle aged offspring of Non- diabetic parents (Controls). All participants had a sedentary life style.BMI, Blood pressure and glycemic status was matched between cases and controls. Alcoholics, smokers, subjects with peripheral vascular disease and other illness were excluded. Arterial stiffness was assessed from Reflective Index (RI) and Stiffness Index (SI). Reflective index and Stiffness index was measured using IR1 model digital finger tip photo pulse plethysmograph. Results: Controls RI- MEAN – 47.9 ±2.8%,SI –MEAN 6 ±.7 m/s and Cases -RI- MEAN -55.1± 3.6%,SI MEAN 7±.9 m/s. Paired ‘t ‘test was applied and it showed statistical significance with p value < .001.We conclude that vascular endothelial dysfunction and
arterial stiffness is present from an early stage in subjects with family history of diabetes. Life style modifications are suggested to improve the vessel wall compliance and prevent further progression.

Keywords: Stiffness index, Reflective index, Diabetes mellitus

 Citation:

Niruba R., Subha K. C., Vijayalakshmi I.. ASSESSMENT OF ARTERIAL STIFFNESS AMONG MIDDLE AGED OFFSPRING OF DIABETIC PARENTS International Journal of Current Research and Review. 6(24), December, 31-34

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A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
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List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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