IJCRR - 7(14), July, 2015
CONSEQUENCE OF FULLERENE NANOPARTICLE (C60) ON OXYGEN CONSUMPTION AND BEHAVIOURAL MODIFICATION IN ETROPLUS MACULATUS
Author: N. Sumi, K.C. Chitra
Background: Fullerenes are nanoparticles composed fully of carbon molecule that are widely used in industry, mostly cosmetics and also play an important role as antioxidants.
Aim: The present study was aimed to evaluate the consequence of fullerene toxicity on oxygen consumption and behavioural modification in cichlid fish, Etroplus maculatus.
Methods: Fishes were exposed at 100 μg/ L concentration of fullerene through fish feed for 96 h. Body weight of the animals, weights of gill, liver, brain and gonads along with mucous deposition was observed. Oxygen consumption of control and treatment groups was evaluated. Behavioural modification of fishes after exposure to fullerene was recorded throughout the study.
Result: Oxygen consumption was decreased at the end of treatment. Weights of fish were decreased and there was significant increase in mucous deposition throughout the body of treated animal. Weights of gill, liver, brain, ovary and testis decreased significantly than that of control fish. Alterations in behavioural patterns including erratic swimming and surfacing activity, slow opercular movements, reddening of skin and haemorrhage through surface of the body were well marked during the period of trial. However, no mortality was observed throughout the study.
Conclusion: The present study accordingly reveals that fullerene induced alteration on oxygen consumption and behaviour in fish.
Keywords: Fullerene, Behaviour, Etroplus maculatus, Oxygen consumption, Fish feed
N. Sumi, K.C. Chitra. CONSEQUENCE OF FULLERENE NANOPARTICLE (C60) ON OXYGEN CONSUMPTION AND BEHAVIOURAL MODIFICATION IN ETROPLUS MACULATUS International Journal of Current Research and Review. 7(14), July, 40-44
1. Tong J, Zimmerman MC, Li S, Yi X, Luxenhofer R, Jordan R, Kabanov AV. Neuronal uptake and intracellular superoxide scavenging of a fullerene (C60)-poly(2-oxazoline)s nanoformulation. Biomaterials 2011; 32: 3654-65.
2. Cai X, Jia H, Liu Z, Hou B, Luo C, Feng Z, et al. Polyhydroxylated fullerene derivative C60(OH)24 prevents mitochondrial dysfunction and oxidative damage in an MPP+ induced cellular model of Parkinson’s disease. J Neurosci Res 2008; 86: 3622- 34.
3. Usenko CY, Harper SL, Tanguay RL. Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish. Toxicol Appl Pharmacol 2008; 229: 44-55.
4. APHA. Standard methods for the examination of water and waste water, 20th Edition, Washington, DC. 1998.
5. Welsh JH, Smith RI. Laboratory Exercise in Invertebrate Physiology. Burgess Publishing Co., Minneapolis. 1961.
6. Vidya PV, Chitra KC. Elevation of reactive oxygen species in hepatocytes of tilapian fish when exposed to silicon dioxide: A potential environmental impact of nanomaterial. Int J Recent Sci Res 2015; 6(3): 2990-5.
7. Bernet D, Schmidt H, Meier W, Burkhardt-Holm P, Wahli T. Histopathology in fish: proposal for a protocol to assess aquatic pollution. J Fish Diseases 1999; 22: 25-34
. 8. Mukadam M, Kulkarni A. Acute toxicity of cypermethrin, a synthetic pyrethroid to estuarine clam Katelysia opima (Gmelin) and its effect on oxygen consumption. J Agri Chem Environ 2014; 3: 139-43.
9. Smith CJ, Shaw BJ, Handy RD. Toxicity of single walled carbon nanotubes to rainbow trout, (Oncorhynchus mykiss): Respiratory toxicity, organ pathologies, and other physiological effects. Aquatic Toxicol 2007; 82: 94-100.