INFLUENCE OF BREAST CANCER ON SERUM TESTOSTERONE AND SEX HORMONE BINDING
GLOBULIN LEVELS AMONG SUDANESE LADIES

Kamal Eldin Ahmed Abdelsalam

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IJCRR - 7(7), April, 2015

Pages: 18-21

INFLUENCE OF BREAST CANCER ON SERUM TESTOSTERONE AND SEX HORMONE BINDING
GLOBULIN LEVELS AMONG SUDANESE LADIES

Author: Kamal Eldin Ahmed Abdelsalam

Category: Healthcare

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Abstract:

Background: Breast cancer is the most frequent cancer and the second leading cause of cancer deaths among women worldwide and an increasing incidence rate has been observed in Sudan.
Objective: this study was aimed to determine the effect of breast cancer on testosterone and sex hormone binding globulin inSudanese female patients.
Materials: This study included 120 untreated breast cancer patients with clinical and histopathological evidence and 100 healthy volunteers as a control. Venous blood was drawn from the cases and controls.
Methods: Testosterone and sex hormone binding globulin were estimated in blood samples by using radio-immune assay. Paired t-test was used to compare the mean serum levels of testosterone and sex hormone binding globulin between patients and controls.
Results: In the present study there were significant high levels of serum testosterone in premenopausal lady patients with breast cancer as compared to control group (p value <0.05). On the other hand, there were significant low levels of sex hormone binding
globulin in ladies with breast cancer when compared to controls (p value<0.05).
Conclusion: A significant high level of testosterone and low level of sex hormone binding globulin were found in this study.

Keywords: Testosterone, Sex hormone binding globulin, Breast cancer

Citation:

Kamal Eldin Ahmed Abdelsalam. INFLUENCE OF BREAST CANCER ON SERUM TESTOSTERONE AND SEX HORMONE BINDING
GLOBULIN LEVELS AMONG SUDANESE LADIES International Journal of Current Research and Review. 7(7), April, 18-21

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INFLUENCE OF BREAST CANCER ON SERUM TESTOSTERONE AND SEX HORMONE BINDING
GLOBULIN LEVELS AMONG SUDANESE LADIES