IJCRR - 7(7), April, 2015
A COMPARATIVE STUDY OF CARDIAC FUNCTIONS IN TOBACCO SMOKERS AND NON SMOKERS AMONG ADULT MALES IN AND AROUND SULLIA
Author: Anandkumar, Shilpa Patil, Shobith Bangera, Urban D. Souza
Background: Cigarette smoking is one of the common cause of Hypertension. Hence the present study is conducted to evaluate the effect of smoking on cardiac functions among healthy individuals as the previous studies done have conflicting results.
Objectives: To evaluate the cardiac functions among smokers and non smokers in Sullia
Methods: The present study was carried out on 100 apparently healthy male subjects included 50 smokers (study group) and 50 non – smokers (control group) in the age group of 18 to 30 years. Cardiac parameters were compared between smokers and non-smokers. Stastistical analyses was performed using student’s t-test for 2 group comparisons.
Results: In this study the effect of smoking on cardiac parameters like Resting Heart Rate(RHR), Diastolic Blood Pressure(DBP) and on Mean Blood Pressure(MBP) is negligible except on Systolic Blood Pressure (SBP) in which there is statistically significant decrease in blood pressure in smokers compared to non smokers.
Conclusion: There was significant decrease in Systolic Blood Pressure (SBP) among smokers compared to non-smokers.In the present study Blood Pressure(BP) levels in smokers was rarely recorded during or immediately after smoking when acute rises in BP occur due to nicotine induced adrenergic drive, therefore BP levels of smokers tend to be systematically underestimated. The acute rise in BP may be followed by reduction due to body’s homeostatic mechanism to maintain BP which may be attributed to rebound phenomenon and the adaptation process. Futher study has to be conducted between young and old age smokers with large sample size taking into consideration the time of sampling i.e taking the readings immediately after smoking.
Keywords: RHR, DBP, SBP, MBP
Anandkumar, Shilpa Patil, Shobith Bangera, Urban D. Souza. A COMPARATIVE STUDY OF CARDIAC FUNCTIONS IN TOBACCO SMOKERS AND NON SMOKERS AMONG ADULT MALES IN AND AROUND SULLIA International Journal of Current Research and Review. 7(7), April, 01-05
1. Sinha DN, Gupta PC, Pednekar MS. Tobacco use in a rural area of Bihar. Indian J Community Med 2003;28(4): 10–12
2. Murray CJ, Lopez AD.eds. The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020. Cambridge, Massachussets: Harvard School of Public Health, 1996.)
3. Burns DM. Nicotine Addiction. In: Kasper, Fauci B, Longo, Houser, Jameson, eds. Harrison’s Principles of Internal Medicine. (vol.2). 16th edn. New York: McGraw-Hill; 2005.p.2574.
4. Berglund G, Wilhelmsen L. Factors related to blood pressure in a general population sample of Swedish men. Acta Med Scand. 1975;198:291–8.
5. Lakier JB. Smoking and cardiovascular disease. Am J Med 1992;93:8–12S.
6. Czernin J, Waldherr C. Cigarette smoking and coronary blood flow. Prog Cardiovasc Dis 2003;45:395–404.
7. Cryer PE, Haymond MW, Santiago JV, Shah SD. Norepinephrine and epinephrine release and adrenergic mediation of smoking-associated hemodynamic and metabolic events. N Engl J Med. 1976;295:573–7.
8. Tuomilehto J, Elo J, Nissmen A. Smoking among patients with malignant hypertension. BMJ. 1982;1:1086.
9. Hughes k, Leong WP, Sothy SP, Lun KC, Yeo PPB. “Relationships between cigarette smoking, blood pressure and serum lipids in the Singapore general population,” International Journal of Epidemiology. 1993;22( 4) 637–43.
10. MacMahon S, Peto R, Cutler J, Collins R, Sorlie P, Neaton J et al. Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet. 1990;335:765–74.
11. Ariesen MJ, Claus SP, Rinkel GJ, Algra A. Risk factors for intracerebral hemorrhage in the general population: a systematic review. Stroke. 2003; 34:2060–5.
12. Tuut M, Hense HW. Smoking, other risk factors and fibrinogen levels: evidence of effect modification. Ann Epidemiol. 2001;11:232–8.
13. Howard G, Wagenknecht LE, Burke GL, Diez-Roux A, Evans GW, McGovern P et al. Cigarette smoking and progression of atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) Study. JAMA. 1998;279:119–24.
14. Labarthe DR. Epidemiology and Prevention of Cardiovascular Diseases: A Global Challenge. Gaithersburg, MD: Aspen Publication Inc; 1998.
15. Roberto F, Annalisa Z, Paola L, Gianluigi M, Gianmarco V, Alessandro V. Cigarette Smoking and Blood Pressure in a Worker Population: A Cross-Sectional Study. European Journal of Cardiovascular Prevention and Rehabilitation. February 1996; 3(1): 55–9.
16. Junichi M, Toshihiko I, Hiroaki M. Effects of Smoking Cessation on Blood Pressure and Heart Rate Variability in Habitual Smokers. Hypertension 1999;33:586–90.
17. Benowitz NL, Kuyt F, Jacob P. Influence of nicotine on cardiovascular and hormonal effects of cigarette smoking. Clin Pharmacol Ther. 1984;36:74–81.
18. Benowitz NL, Gourlay SG. Cardiovascular toxicity of nicotine: implications for nicotine replacement therapy. J Am Coll Card 1997; 29:1422–31.
19. Manfred S, Eliezer J, Yair L. Blood pressure in smokers and nonsmokers: Epidemiologic findings American Heart Journal. 1986 May; 111( 5): 932–40.
20. Koichi H, Hiroaki T, Munehiro S, Suminori K, Jun S, Kikuo A. Relationship of cigarette smoking to blood pressure and serum lipids. Atherosclerosis. 1990 October; 84( 2-3): 189–93.
21. Okubo Y , Miyamoto T, Suwazono Y , Kobayashi E and Nogawa K. An association between smoking habits and blood pressure in normotensive Japanese men. Journal of Human Hypertension .2002; 16: 91–6.
22. Yasushi O, Yasushi S, Etsuko K, Koji Nogawa . An association between smoking habits and blood pressure in normotensive Japanese men: a 5-year follow-up study. Drug and Alcohol Dependence. 2004 February 7; 73(2):167–74.
23. Hongmei L, Weijun T, Aili W, Zhe L, Yonghong Z. Effects of cigarette smoking on blood pressure stratified by BMI in Mongolian population, China. Blood Pressure. April 2010;19(2):92–7.
24. Higgins MW, Kjelsberg M. Characteristics of smokers and nonsmokers in Tecumseh, Michigan. II. The distribution of selected physical measurements and physiologic variables and the prevalence of certain diseases in smokers and nonsmokers. Am J Epidemiol 1967; 86: 60–77.
25. Hansen KW, Pedersen MM, Christiansen JS, Mogensen CE. Night blood pressure and cigarette smoking: disparate association in healthy subjects and diabetic patients. Blood Press 1994;3: 381–8.
26. Omvik P. How smoking affects blood pressure. Blood Press 1996;5:71–7. 27. Trap-Jensen J. “Effects of smoking on the heart and peripheral circulation.” American Heart Journal.1988; 115(1):263–7.
28. Leone A. “Biochemical markers of cardiovascular damage from tobacco smoke.” Current Pharmaceutical Design. 2005; 11(17): 2199–208.