IJCRR - 7(15), August, 2015
Pages: 21-25
FUNGAL INFECTIONS - A CLINICOMORPHOLOGICAL SPECTRUM
Author: Thamil Selvi Ramachandran, K. Sivakami, Prakash H. Muddegowda, P. Venukeerthan
Category: Healthcare
[Download PDF]
Abstract:
Introduction: Fungal infections at different sites are showing increasing incidence in both healthy and Immunocompromised individuals. Among the fungal infections, Aspergillus and Mucormycosis are the common infections, involving maxillary sinus, oral cavity, lung followed by each case of maduramycosis of foot and mucormycosis of forearm in this study.
Aims: To study the clinical and pathological profile of fungal infections at various sites.
Settings and Design: A Retrospective observational study conducted in Department of Pathology from Jan 2011- Dec 2012, VMKV medical college, Salem.
Material and Methods: Seventeen cases were analyzed in this study with respect to clinical history, physical examination and neuroimaging [computed tomography (CT) or magnetic resonance imaging (MRI)] wherever necessary. Operated specimens were received in 10% formalin for histopathological examination.
Results: Male:female ratio was 11:6. Mean age of 49 years. The common clinical presentations were nasal discharge followed by oral ulcer and foot ulcer. Commonest site of lesion was nasal cavity (59%). Mucormycosis was the commonest fungus.
Conclusions: Early diagnosis and prompt treatment can reduce the mortality and morbidity of this lethal fungal infection.
Keywords: Fungal infections, Mucormycosis, Aspergillus, Oral ulcer
Citation:
Thamil Selvi Ramachandran, K. Sivakami, Prakash H. Muddegowda, P. Venukeerthan. FUNGAL INFECTIONS - A CLINICOMORPHOLOGICAL SPECTRUM International Journal of Current Research and Review. 7(15), August, 21-25
References:
1. Leitner C, Hoffmann J, Zerfowski M, Reinert S. Mucormycosis: necrotizing soft tissue lesion of the face. J Oral Maxillofac Surg 2003;61:1354-8.
2. Pogrel MA, Miller CE. A case of maxillary necrosis. J Oral Maxillofac Surg 2003;61:489-93.
3. Zapico ADV, Suarez AR, Encinas PM, Angulo CM, Pozuelo EC. Mucormycosis of the sphenoidal sinus in an otherwise healthy patient. Case report and literature review. J Laryngol Otol 1996;110:471-3.
4. Jones AC, Bentsen TY, Fredman PD. Mucormycosis of the oral cavity. Oral Surg Oral Med Oral Pathol 1993;75: 455-60.
5. Paulltauf A. Mycosis mucorina. Virchows Arch [A]. 1885, 102- 543.
6. Stammberger M,Jakes R, Beaufort, Austria G. Aspergillosis of the paranasal sinuses: X-ray diagnosis, histopathology and clinical aspects. Ann Otol Rhino Laryngol 1984; 93:251-6.
7. Katzenstein AA, Sale SR, Greenberger PA. Allergic Aspergillus sinusitis. A newly recognized form of sinusitis. The Laryngoscope 1983;72:89-93.
8. Yohai RA, Bullock JD, Aziz AA et al, Survival factors in Rhinoorbito-cerebral mucormycosis. Surv opthalmol:1994; 39:3-22
9. Achkar JM, Fries BC. Candida infections of the genitourinary tract. Clin Microbiol Rev. 2010;23(2):253-73.
10. Sinha A, Phukan JP, Bandopadhyay G, Sengupta S, Bose K, Mondal RK, et al. Clinicopathological study of rhinosporidiosis with special reference to cytodiagnosis. J Cytol 2012;29(4):246- 9.
11. Bonifaz A, Tirado-Sánchez A, Calderón L, Saúl A, Araiza J, Hernández M, et al. (2014) Mycetoma: Experience of 482 Cases in a Single Center in Mexico. PLoS Negl Trop Dis 8(8): e3102. doi:10.1371/journal.pntd.0003102
|