IJCRR - 7(16), August, 2015
Pages: 62-67
AN ANALYSIS OF THE ROLE OF UTERINE MALFORMATIONS IN PRIMARY INFERTILITY - AN OBSERVATIONAL STUDY
Author: A. Jayashree, Udaya Kumar P., V. Padmaja, L. Vinodini, K. Sudha Rani
Category: Healthcare
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Abstract:
Introduction: According to World Health Organization worldwide estimates 60-80 million couples suffer from infertility. Infertility or the inability of a female to conceive despite 12 months or more of unprotected coital exposure can be due to several factors including uterine anomalies, tubal anomalies, and hormonal imbalance among others.
Aims and Objectives: The scope of this study includes impact of Uterine Anomalies on primary infertility.
Materials and Methods: The study includes evaluation and investigation of 100 cases of infertile females and women with bad obstetric history over a period of 3 years from 2007 to 2009 in Gandhi Hospital, Secunderabad, Telangana. A detailed history for every complaint in all the cases was taken by the in charge gynaecologist.
Results: In the present study the bicornuate uterus predominates with 40% (4 cases out of 100). Septate uterus and uterus didelphys were observed in 2 cases each (20%), whereas arcuate uterus and unicornuate uterus were observed in 1 case each (10%).
Conclusion: It is pertinent to note that, a fairly high incidence of bicornuate uterus and uterus didelphys with poor reproductive outcome in the present study provokes a challenge in terms of management protocol on account of its morbidity and demands a meticulous antenatal surveillance. Considering the low socioeconomic and rural background in most of the cases in this study, it is worthwhile to investigate whether nutritional and environmental factors play a role in the genesis of the reproductive system.
Keywords: Uterine anomalies, Primary infertility, Bicornuate uterus, Uterus didelphys, Septate uterus, Arcuate uterus, Unicornuate uterus
Citation:
A. Jayashree, Udaya Kumar P., V. Padmaja, L. Vinodini, K. Sudha Rani. AN ANALYSIS OF THE ROLE OF UTERINE MALFORMATIONS IN PRIMARY INFERTILITY - AN OBSERVATIONAL STUDY International Journal of Current Research and Review. 7(16), August, 62-67
References:
1. Susan Standring, PhD; Gray’s Anatomy, The Anatomical Basis of Clinical Practice; 40th ed.
2. T. W. Sadler, Ph.D; Langman’s medical embryology, 11th ed. Pg 252 – 253.
3. Infecundity, infertility and childlessness in developing countries. DHS comparative reports No. 9. Calverton Maryland, USA: ORC Macro and the World Health Organization; 2004. World Health Organization.
4. F. Gary Cunningham, MD, John C. Hauth, MD, Kenneth J. Leveno, MD, Larry Gilstrap III, MD, Steven L. Bloom, MD, Katharine D. Wenstrom, MD; Williams Obstetrics, 22nd Ed (2005), p 950-952.
5. House M, Kaplan DL, Socrate S. Relationships between mechanical properties and etracellular matrix constituents of cervical stroma during pregnancy. 2009, 33(5): 300-307.
6. Saravelos S.H., Cocksedge K.A., Li T.C.: Prevalence and Diagnosis of Congenital Uterine Anomalies in Women with Reproductive Failure: A Critical Appraisal. Hum Reprod Update. 2008 Sep-Oct; 14(5): 415-29 PMID: 18539641.
7. Grigoris F. Grimbizis, Michel Camus, Basil C. Tarlatzis, John N. Bontis and Paul Devroey: Clinical Implications of Uterine Malformations and Hysteroscopic Treatment Results. Human Reproduction Update 2001; Vol.7 No.2 pp.161-174.
8. Tulandi T., Arronet G.H., McInnes R.A.: Arcuate and Bicornuate Uterine Anomalies and Infertility. Fertil Steril October 1980; 34(4): 362-4 PMID: 7418888.
9. Pentti K. Heinonen, Seppo Saarikoski and Paavo Pystynen: Reproductive Performance of Women with Uterine Anomalies: An evaluation of 182 Cases. Acta Obstetricia et Gynecologica Scandinavica 1982; Vol. 61 No. 2, Pages 157-162.
10. Heinonen P.K., Pystynen P.P.: Primary Infertility and Uterine Anomalies. Fertil Steril. 1983 Sep; 40(3): 311-6 PMID: 6884534
11. Pedro Acién: Reproductive Performance of Women with Uterine Malformations. Human Reproduction 1993; Vol. 8 No. 1 pp. 122-126.
12. Pedro Acién, and Maribel Acién: Evidence-based Management of Recurrent Miscarriage. International Congress Series April 2004; Volume 1266 Pages 335-342.
13. A. M. Khalil, G. B. Azar, A. B. Hannoun, J. T. Sawaya, A. A. Abu-Musa and K. S. Karam: Reproductive Outcome Following Abdominal Metroplasty. International Journal of Gynecology and Obstetrics May 1995; Volume 49 Issue 2 Pages 157-160.
14. Francisco Raga, Celia Bauset, Jose Remohi, Fernando BonillaMusoles, Carlos Simon, Antonio Pellicer: Reproductive Impact of Congenital Mullerian Anomalies. Human Reproduction. 1997; 2277–2281.
15. Bruseo G.F, Arena S., Angelini A.: Role of Diagnostic Hysteroscopy in Infertile Women. Minerva Gynecol. 2001 Oct; 53(5): 313-9 PMID: 11549995.
16. Lin Paul C.; Bhatnagar Kunwar P.; Nettleton G. Stephen; Nakajima Steven T.: Female Genital Anomalies Affecting Reproduction. Fertility and Sterility 2002; 78(5): 899-915.
17. Pui M.H.: Imaging Diagnosis of Congenital Uterine Malformation. Comput Med Imaging Graph 2004 Oct; 28(7): 425-33 PMID: 15464882.
18. Braun P., Grau F.V., Pons R.M., Enguix D.P.: Role of Hysterosalpingography in diagnosis of uterine malformations. Eur J. Radiol. 2005 Feb; 53(2): 274-9 PMID: 15664292.
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