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IJCRR - 7(16), August, 2015

Pages: 22-29

IMPORTANCE OF CLINICAL HISTORY AND ENDOMETRIAL HISTOMORPHOLOGY IN TREATMENT DYSFUNCTIONAL UTERINE BLEEDING

Author: Panchal Nirav S., Baxi Seema N.

Category: Healthcare

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Abstract:

Introduction: Dysfunctional Uterine Bleeding (DUB) seen in 10-15% of women attending gynaecological clinic has variations in endometrial patterns. Modern treatment depends upon physiology and morphological pattern.
Aims: This study was undertaken to analyse types, frequencies and histomorphology of DUB in a part of India where this was the first study of its kind, to analyse hormonal effects and to evaluate percentage of hyperplasia and pre-neoplastic features as per WHO 2008 and Endometrial Intraepithelial Neoplasia (EIN) criteria.
Method: 237 curettage and 126 hysterectomy samples of DUB patients were assessed between July 2012 - July 2013 in a tertiary care teaching hospital.
Results: DUB was common between 31-50 years. Adolescents were not seen to have DUB. Early menopause at 40 years was seen in 14.3% cases. Ovulatory cases comprised 34.7% and anovulatory 50.5%. Hyperplasia comprised 5.5% and 1.7% had malignancy. One case of simple hyperplasia had EIN. Tuberculous endometritis is not common in our district though pulmonary tuberculosis is rampant.
Conclusion: Regional differences in age of presentation and socioeconomic differences in organic pathologies are noted in different parts of India. Different treatment options make it essential to differentiate DUB into ovulatory/anovulatory, disordered proliferative endometrium or hyperplasia.

Keywords: Dysfunctional uterine bleeding, Exogenous hormones induced endometrial changes, Endometrial intraepithelial neoplasia, Endometrial hyperplasia, Disordered proliferative endometrium

Citation:

Panchal Nirav S., Baxi Seema N.. IMPORTANCE OF CLINICAL HISTORY AND ENDOMETRIAL HISTOMORPHOLOGY IN TREATMENT DYSFUNCTIONAL UTERINE BLEEDING International Journal of Current Research and Review. 7(16), August, 22-29

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