IJCRR - 7(16), August, 2015
IMPORTANCE OF CLINICAL HISTORY AND ENDOMETRIAL HISTOMORPHOLOGY IN TREATMENT DYSFUNCTIONAL UTERINE BLEEDING
Author: Panchal Nirav S., Baxi Seema N.
Introduction: Dysfunctional Uterine Bleeding (DUB) seen in 10-15% of women attending gynaecological clinic has variations in endometrial patterns. Modern treatment depends upon physiology and morphological pattern.
Aims: This study was undertaken to analyse types, frequencies and histomorphology of DUB in a part of India where this was the first study of its kind, to analyse hormonal effects and to evaluate percentage of hyperplasia and pre-neoplastic features as per WHO 2008 and Endometrial Intraepithelial Neoplasia (EIN) criteria.
Method: 237 curettage and 126 hysterectomy samples of DUB patients were assessed between July 2012 - July 2013 in a tertiary care teaching hospital.
Results: DUB was common between 31-50 years. Adolescents were not seen to have DUB. Early menopause at 40 years was seen in 14.3% cases. Ovulatory cases comprised 34.7% and anovulatory 50.5%. Hyperplasia comprised 5.5% and 1.7% had malignancy. One case of simple hyperplasia had EIN. Tuberculous endometritis is not common in our district though pulmonary tuberculosis is rampant.
Conclusion: Regional differences in age of presentation and socioeconomic differences in organic pathologies are noted in different parts of India. Different treatment options make it essential to differentiate DUB into ovulatory/anovulatory, disordered proliferative endometrium or hyperplasia.
Keywords: Dysfunctional uterine bleeding, Exogenous hormones induced endometrial changes, Endometrial intraepithelial neoplasia, Endometrial hyperplasia, Disordered proliferative endometrium
Panchal Nirav S., Baxi Seema N.. IMPORTANCE OF CLINICAL HISTORY AND ENDOMETRIAL HISTOMORPHOLOGY IN TREATMENT DYSFUNCTIONAL UTERINE BLEEDING International Journal of Current Research and Review. 7(16), August, 22-29
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