Formulation and Evaluation of Euterpeoleracea In-Situ Gel for Better Treatment of Conjunctivitis

Kanuri Spandana; Ramineni Shireesh Kiran; Ganti Subrahmanya Sharma; Tadikonda Rama Rao

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IJCRR - 14(17), September, 2022

Pages: 01-06

Formulation and Evaluation of Euterpeoleracea In-Situ Gel for Better Treatment of Conjunctivitis

Author: Kanuri Spandana, Ramineni Shireesh Kiran, Ganti Subrahmanya Sharma, Tadikonda Rama Rao

Category: Healthcare

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Abstract:

Introduction: This study is to formulate the Euterpe Oleracea in-situ gel for better treatment of conjunctivitis. The Euterpe Oleracea ophthalmic drug solution can treat the ocular infections effectively.
Aim: Formulation and evaluation of Eutepe Oleracea in-situ gel for better treatment of conjunctivitis
Methodology: Euterpe Oleracea drug containing in-situ gel prepared by using different polymers like carbopol-940, HPMC K15, HPMC K100, HPMC K4M, as a pH triggered gelling system, these polymers are used to controlled release to increase bioavailability.
Result: After the formulation prepared it will undergo evaluation i.e. visual appearance, pH, clarity checking, gel capacity, drug content and rheological studies, in-vitro drug release studies, sterility testing were determined. The prepared in situ gel was clear and transparent, it is having good gelling capacity.
Conclusion: The drug content of these formulations was determined to be 98%. Developed formulation was stable, and non-irritant, effective therapeutically it can be release in the form of sustained release.

Keywords: Euterpe Oleracea, HPMC, Citric acid, Disodium hydrogen phosphate, Tween-80, Benzalkonium chloride

DOI URL: https://doi.org/10.31782/IJCRR.2022.141701

Citation:

Kanuri Spandana, Ramineni Shireesh Kiran, Ganti Subrahmanya Sharma, Tadikonda Rama Rao. Formulation and Evaluation of Euterpeoleracea In-Situ Gel for Better Treatment of Conjunctivitis International Journal of Current Research and Review. 14(17), September, 01-06

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