IJCRR - 7(19), October, 2015
SALBUTAMOL NEBULISATION: IS IT A PREDISPOSING FACTOR FOR POSTOPERATIVE ATRIAL FIBRILLATION IN CORONARY ARTERY BYPASS GRAFTING PATIENTS?
Author: Megha Shah, Hetal D. Shah
Background: Atrial fibrillation (AF) is one of the known complications of cardiac surgery and represents a major cause of morbidity. However, improvements in surgical and anaesthesia technique and controlling various predisposing factors have not helped to curb the incidence. Therefore, search is going on for various modalities to decrease the incidence.
Aim: This retrospective study was conducted to evaluate the risk of AF with nebulised ß2 agonists in postoperative cardiac bypass surgery patients.
Methods: In this observational study, data of 100 eligible patients operated for coronary artery bypass grafting (CABG) was collected. Patients were divided in two groups: Group A: Patients who had received postoperative nebulised salbutamol Group B: Patients who had not received postoperative nebulised salbutamol The data was analyzed for onset, duration, severity, treatment, outcome of post operative AF (POAF) and also regarding dose, duration of salbutamol.
Results: POAF occurred frequently in patients who had received nebulised salbutamol (p<0.05). ICU and hospital stay was also prolonged in Group A. However, none of the patients had fatal postoperative complication.
Conclusion: Salbutamol nebulisation in post CABG patients could be an additional risk factor for POAF.
Keywords: Atrial fibrillation, ß2 agonists, Post cardiac surgery patients, Salbutamol nebulisation
Megha Shah, Hetal D. Shah. SALBUTAMOL NEBULISATION: IS IT A PREDISPOSING FACTOR FOR POSTOPERATIVE ATRIAL FIBRILLATION IN CORONARY ARTERY BYPASS GRAFTING PATIENTS? International Journal of Current Research and Review. 7(19), October, 16-19
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